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Brand Name :
N/A
Synonyms :
Class :
Antipyretic,Analgesic,NSAID
Brand Name :
N/A
Synonyms :
Class :
Antipyretic,Analgesic,NSAID
Dosage forms & Strengths
Tablet
100mg
200mg
Take the tablet orally once or twice based on the amount of pain
Take the tablet orally once or twice based on the amount of pain
Safety and efficacy is not established in pediatrics
Refer to the adult dosing
Action and Spectrum
feclobuzone belongs to the pyrazolone class and has analgesic and antipyretic properties. It acts by inhibiton of the cyclooxygenase enzyme. It acts as a binding molecule to the three carbon like proteinase for the severe acute respiratory syndrome when seen through virtual screening.
Frequency not defined
GI bleeding
GI upset
Skin rash
Headache
Edema
Fluid retention
Dizziness
Difficulty breathing
Renal and hepatic problems
CVS events
Nausea
Stomach pain
Blackbox warning
Patients suffering from gastrointestinal issues must cautious as it will increase the complications such as ulcer and intestinal bleeding. Heart strokes are also caused with patients of pre-existing conditions.
Contraindication/Caution:
Contraindications
Cautions
Pregnancy consideration:
No data is available regarding the administration of the drug during pregnancy.
Breastfeeding warnings:
No data is available regarding the excretion of drug in breast milk.
Pregnancy categories:
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology
It works by inhibiting the cyclooxygenase enzymes, namely cyclo-oxygenase-one and two, which affects prostaglandins production and mediates raise in the body temperature, swelling and redness along with discomfort.
Pharmacodynamics
Feclobuzone acts by stopping the activity of COX enzymes, leading to the reduced levels of prostaglandins
Pharmacokinetics
Limited data available on the ADME
Administration
It is used orally in the form of tablets
Patient information leaflet
Generic Name: feclobuzone
Pronounced: feh-KLOH-byoo-zone
Why do we use feclobuzone?
Feclobuzone acts as an antipyretic, analgesic and anti-inflammatory agents.
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