ferumoxytol

Action and Spectrum

Drug Interaction

Adverse Reaction

1-10%: 

Headache  

Nausea  

Dizziness  

Hypotension  

Peripheral edema  

Edema  

Vomiting  

Fatigue  

Abdominal pain  

Chest pain 

Cough  

Pruritus  

Pyrexia 

Diarrhea  

Back pain  

Muscle spasms  

Dyspnea  

Rash 

<1%: 

Hypotension  

Chest pain  

Arthralgia  

Dyspnea  

Flushing  

Chest discomfort  

Nausea  

Back pain  

Dizziness 

Headache 

Frequency undefined: 

Loss of consciousness 

Angioedema 

Unresponsiveness 

Pulse absent 

Syncope 

Cyanosis 

Ischemic myocardia 

Hypotension 

Hypotension 

Cardiac arrest 

Heart failure 

Black Box Warning

Contraindication / Caution

Ferumoxytol is contraindicated in patients hypersensitive to the active ingredient. 

Pregnancy / Lactation

Pregnancy consideration:  

Ferumoxytol may show adverse effects on the fetus in the second and third trimesters of pregnancy. 

Breastfeeding warnings:  

No data is available regarding the excretion of the drug in breast milk. 

Pregnancy category: 

• Category A: well-controlled and Satisfactory studies do not show risk to the fetus in the first/later trimester.        
• Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women        
• Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.       
• Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.        
• Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.        
• Category N: There is no data available for the drug under this category 

Pharmacology

Adminstartion

Patient Information Leaflet

Patient information leaflet 

Generic Name: ferumoxytol 

Pronounced: fayr-yoo-MOK-sih-tol 

Why do we use ferumoxytol? 

Ferumoxytol is an iron product. It is used to treat iron deficiency anemia.