From Data to Decisions: Tailoring Treatment for Pituitary Tumors
February 3, 2026
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Brand Name :
Toviaz
(Canada) [Available]Synonyms :
Class :
Anticholinergic and Urinary antispasmodics
Brand Name :
Toviaz
(Canada) [Available]Synonyms :
Class :
Anticholinergic and Urinary antispasmodics
Dosage Forms & Strengths :
Tablet-ER
4mg
8mg
4 mg orally every day; may increase up to 8 mg orally a day based upon tolerability and response
Dosage Modifications
Renal impairment
Mild-to-moderate: Not required
CrCl <30 mL/min: do not exceed 4 mg orally per day
Dosage Forms & Strengths
Tablet-ER
4mg
8mg
Neurogenic Detrusor Overactivity
Age: ≥6 years
Weight: >25-35 kg
4 mg orally every day; can increase dose up to 8 mg per day as needed
Age: ≥6 years
Weight: >35 kg
4 mg orally every day; can increase dose up to 8 mg per day after one week
When fesoterodine is used together with profenamine, this leads to enhanced risk or seriousness of adverse events
Adverse drug reactions:
Frequency Defined
10%
Diarrhea
Adult overactive bladder
Dry mouth
1-10%
Dyspepsia
Urinary tract infection
Constipation
Abdominal pain
Weight increased
Headache
Adult overactive bladder
Dry throat
Insomnia
Rash
Urinary tract infection
Dry mouth
Back pain
Nausea
Peripheral edema
Upper abdominal pain
Pregnancy warnings:
Pregnancy category: N/A
Breastfeeding warnings:
The release of the drug into the human breastmilk is unknown
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits
Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: fesoterodine
Pronunciation: FES-oh-TER-oh-deen
Why do we use fesoterodine?
fesoterodine belongs to the class of anticholinergic agents used to treat overactive bladder, and neurogenic detrusor overactivity in pediatrics
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