finasteride and tadalafil

Action and Spectrum

Drug Interaction

Adverse Reaction

>10%: 

Impotence 

1-10%: 

Decreased libido 

Postural hypotension  

Dizziness  

Abnormal ejaculation  

Asthenia  

Decreased ejaculate volume  

Sexual function abnormal  

Gynecomastia 

Headache  

Breast enlargement  

Somnolence  

Peripheral edema  

Hypotension  

Rhinitis 

<1: 

Ejaculation disorder 

Breast tenderness 

Rash Dyspnea 

Black Box Warning

Contraindication / Caution

Finasteride/tadalafil is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients. 

Pregnancy / Lactation

Pregnancy consideration:  

The drug is contraindicated during pregnancy. 

Breastfeeding warnings:  

The drug is not indicated during lactation. 

Pregnancy category: 

• Category A: well-controlled and Satisfactory studies do not show risk to the fetus in the first/later trimester.        
• Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women        
• Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.       
• Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.        
• Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.        
• Category N: There is no data available for the drug under this category 

Pharmacology

Adminstartion

Patient Information Leaflet

Patient information leaflet 

Generic Name: finasteride/tadalafil 

Pronounced: fin-as-ter-ide/tad-ala-fil 

Why do we use finasteride/tadalafil? 

Finasteride/tadalafil belongs to the category of Phosphodiesterase Enzyme Inhibitors. It helps to treat Benign Prostatic Hyperplasia.