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Brand Name :
No Data Available.
Synonyms :
flurbiprofen
Class :
Anti-inflammatory drugs and Non-steroidal anti-inflammatory drugs (NSAIDs)
Dosage Forms & Strengths
Tablet, Oral:
50 mg
100 mg
Note: Lowest effective dose should be administered, administration is recommended in combination with proton pump inhibitor in patients with existing or at risk of cardiovascular disease, GI disease, kidney impairment, and chronic liver disease
50 mg oral tablet 2 to 4 times a day
Symptoms exacerbations: 300 mg/day or as per requirement
50 mg oral tablet 4 times a day
200 to 300 mg oral tablet in 2 to 4 divided doses per day (Do not exceed 100 mg/dose)
150 to 300 mg oral tablet in 3 to 4 divided doses per day or as needed
Dose adjustment:
Discontinue the use of flurbiprofen if the patient seems at increased risk of acute kidney injury
Discontinue treatment if any signs and symptoms occur of hepatotoxicity during treatment:
200 to 300 mg oral tablet in 2 to 4 divided doses per day (Do not exceed 100 mg/dose
No safe and efficacious dosing instructions were found.
Refer to adult dosing
Note: For higher doses in patients >60 years of age: Dual antiplatelet or an anticoagulant is recommended.
interaction with NSAIDs may lead to increased toxicity such as myelosuppression, renal toxicity, and GI toxicity
interaction with NSAIDs may lead to increased toxicity such as myelosuppression, renal toxicity, and GI toxicity
When flurbiprofen is used together with sertraline, the risk or seriousness of bleeding may be enhanced
When flurbiprofen is used together with bufexamac, this leads to enhanced risk or seriousness of adverse outcomes
flurbiprofen leads to a reduction in the rate of excretion of nitric oxide, which leads to an increased level of serum
When flurbiprofen is used together with nifenazone, this leads to enhanced risk or seriousness of adverse events
When flurbiprofen is used together with diazoxide, this leads to reduction in therapeutic effectiveness of diazoxide
glycopyrrolate inhaled and formoterol
may decrease the toxic effects of each other by sedation
may enhance the serum concentration of CYP2C9 inhibitors
may have a decrease in excretion when combined with flurbiprofen
Frequency defined:
>10%
Edema
Increased liver enzymes
Abdominal pain
Dyspepsia
Flatulence
Gastrointestinal bleeding
Nausea
vomiting
Tremor
Weakness
Visual disturbance
Amnesia
Drowsiness
Headache
Anxiety
Insomnia
Malaise
Nervousness
Skin rash
<1% postmarketing:
Altered sense of smell
Anemia
Cardiac failure
Cerebra; ischemia
Confusion
Cardiac failure
Epistaxis
Hepatitis
Hepatotoxicity
Stomatitis
Urticaria
Vasodilation
Necrolysis
Peptic ulcer
Pregnancy consideration: Some studies reported the risk of miscarriage associated with NSAIDs
Lactation: flurbiprofen can be excreted in breast milk. The lowest possible dose is recommended for lactating females.
Pregnancy category:
Patient information leaflet
Generic Name: Flurbiprofen
Pronounced: flurbiprofen
Why do we use flurbiprofen?
Flurbiprofen is used to treat different types of arthritis and for acute pain due to inflammation. It can be prescribed by your doctor for many other reasons.