Actions and Spectrum:
fusidic acid is a narrow-spectrum antibiotic that is mainly used to treat infections caused by bacteria such as Staphylococcus aureus and Streptococcus species. It works by inhibiting bacterial protein synthesis, specifically by binding to elongation factor G (EF-G) and preventing the release of ribosomes from mRNA during translation. This leads to the inhibition of bacterial protein synthesis and ultimately results in the death of the bacteria.
fusidic acid is a bacteriostatic antibiotic, meaning that it slows down the growth and replication of bacteria rather than killing them outright. It is effective against Gram-positive bacteria, including many strains of Staphylococcus aureus resistant to other antibiotics.
fusidic acid is mainly used to treat skin and soft tissue infections, such as impetigo, dermatitis, and infected wounds. It is also used with other antibiotics to treat more severe infections, such as osteomyelitis, endocarditis, and pneumonia.