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Brand Name :
Gadavist
Synonyms :
gadobutrol
Class :
Magnetic resonance imaging contrast media
Brand Name :
Gadavist
Synonyms :
gadobutrol
Class :
Magnetic resonance imaging contrast media
Dosing Form & Strengths
Injectable solution
1mmol/mL
0.1 mmol/kg I.e., 0.1 mL/kg IV at a rate of 2 mL/second
Note:
Indicated for use with MRI to detect abnormalities and visualize the disrupted areas in CNS and BBB
Indicated for use with MRI to detect the extent and present malignant breast cancer and to access myocardial perfusion rate in Cardiac
Dosing Form & Strengths
Injectable solution
1mmol/mL
0.1 mmol/kg I.e., 0.1 mL/kg IV at a rate of 2 mL/second
Note:
Indicated for use with MRI to detect abnormalities and visualize the disrupted areas in CNS and BBB
Adverse drug reactions
Frequency Defined
1-10%
Nausea (1.2%)
Headache (1.5%)
<1%
Rash
Pruritus
Injection site reactions
Dysgeusia
Feeling hot
Erythema
Dyspnea
Paresthesia
Dizziness
Vomiting
Post marketing Reports
Nephrogenic systemic fibrosis
Cardiac arrest
Pregnancy warnings:
AU TGA pregnancy category: B3
US FDA pregnancy category: Not assigned
Lactation:
Excreted into human milk is unknown
Pregnancy Categories:
Category A: In the first or second trimester, well-controlled and satisfactory studies show no risk to the fetus.
Category B: Animal studies found no evidence of fetal risk, and there were not enough studies on pregnant women.
Category C: There was evidence of a risk of adverse effects in animal reproduction studies, but no adequate evidence in human studies.
Category D: adequate data available from various platforms with sufficient evidence of human fetal risk, but despite the potential risk, and only used in emergency cases for potential benefits
Category X: The risks of the drugs in this category outweigh the benefits. As a result, pregnant women should avoid these types of drugs.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: gadobutrol
Why do we use gadobutrol?
gadobutrol is a magnetic resonance imaging contrast media used for MRI contrast.
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