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Brand Name :
Oxapex
Synonyms :
hemoglobin crosfumaril
Class :
Blood substitutes and plasma protein fractions
Dosage Forms & Strengths
Injection solution
65 mg/ml
It is indicated to treat or prevent blood loss and shock in animals that have suffered trauma or surgery
Not determined
Refer to adult dosing
Actions and Spectrum
Hemoglobin crosfumaril is a type of hemoglobin that has been modified by a chemical process to make the alpha-subunits of the protein cross-linked with each other.
This is done to improve the stability and oxygen-carrying capacity of the hemoglobin, which can be used as a blood substitute in certain situations.
Frequency not defined
None
Black Box Warning
None
Contraindication/Caution:
None
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
None
Pharmacodynamics
None
Pharmacokinetics
Information not available on ADME.
Administration
Hemoglobin crosfumaril is administered via intravenously or intraosseously.
Patient information leaflet
Generic Name: hemoglobin crosfumaril
Why do we use hemoglobin crosfumaril?
Hemoglobin crosfumaril is used to treat or prevent blood loss and shock in animals that have suffered trauma or surgery.
It is use in captive mustelids, captive rodents, raptors, and captive or pet birds.