inosine pranobex

Action and Spectrum

Actions and Spectrum 

inosine pranobex has antiviral properties and it is effective against different types of viruses, including RNA and DNA viruses. 

Drug Interaction

Adverse Reaction

Frequency not defined  

Nervousness 

Pruritus 

Skin rash 

Hyperuricemia 

Headache  

Insomnia  

Dizziness 

Arthralgia 

Diarrhea 

Gastric distress 

Fatigue 

Constipation 

Increased urine output 

Black Box Warning

Black Box Warning 

None

Contraindication / Caution

Contraindication/Caution: 

Contraindication: 

None  

Caution: 

• Use with caution in patients with a history of urolithiasis, nephrolithiasis and gout.  
• Caution should be taken in patients with certain autoimmune disorders or immunodeficiency conditions. 
• inosine pranobex should be used with caution in patients with mild to moderate renal impairment. 

Pregnancy / Lactation

Pregnancy consideration: 

Pregnancy category: N/A 

Lactation: Excretion into human milk is unknown  

Pregnancy Categories:         

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology  

inosine pranobex increases the host’s natural antiviral defense mechanisms, primarily by stimulating the production of interferons including interferon-alpha and interferon-gamma. 

Pharmacodynamics 

inosine pranobex promotes the activation and proliferation of various immune cells, such as T lymphocytes and natural killer (NK) cells. These cells are involved in recognizing and eliminating infected cells. 

Pharmacokinetics 

Absorption   

inosine pranobex is absorbed from the gastrointestinal tract into the bloodstream.  

Distribution 

inosine pranobex is distributed throughout the body, including different tissues and organs. 

Metabolism 

inosine pranobex undergoes minimal metabolism in the liver.  

Elimination and excretion 

The elimination of inosine pranobex occurs primarily occurs through renal excretion.

Adminstartion

Administration 

inosine pranobex is typically administered orally, and it is available in tables form.

Patient Information Leaflet

Patient information leaflet 

Generic Name: inosine pranobex 

Why do we use inosine pranobex? 

inosine pranobex is used to treat certain viral infections, including influenza, Herpes Simplex Virus (HSV), Human Papillomavirus (HPV). inosine pranobex is used in the treatment of slowly progressive subacute sclerosing panencephalitis (PSSP) and due to this delay in neurologic deterioration and prolong life expectancy.