How Far Is Too Far? The Ethics of Mini Brain Research
December 11, 2025
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Brand Name :
Jack & Jill Cough Syrup (In Canada)
Synonyms :
ipecac syrup
Class :
Antidotes/Emetic agents
Brand Name :
Jack & Jill Cough Syrup (In Canada)
Synonyms :
ipecac syrup
Class :
Antidotes/Emetic agents
Dosage Forms & Strengths
Oral Syrup
7%
Not recommended for poisoning now
Presently, the medication of choice is activated charcoal
15-30 ml orally once
Repeat with 15 ml once again if emesis doesn’t occur within 20-30 minutes
Gastric lavage should be performed if vomiting doesn’t occur 30-45 minutes later the second dose
Intake of the syrup with 3-4 glasses of water
Not recommended for childhood poisoning now
Presently, the medication of choice is activated charcoal
For 6-12 months- 5-10 ml once with half or one cup of water under medical supervision
For 1-12 years- 15 ml orally once with 1-2 glasses of water
Repeat with 15 ml once again if emesis doesn’t occur within 20-30 minutes
For more than 12 years- 15-30 ml orally once with 3-4 glasses of water
Repeat with 15 ml once again if emesis doesn’t occur within 20-30 minutes
Gastric lavage should be performed if vomiting doesn’t occur 30-45 minutes later the second dose
Intake of the syrup with 3-4 glasses of water
Not recommended for childhood poisoning now
Presently, the medication of choice is activated charcoal
For 6-12 months- 5-10 ml once with half or one cup of water under medical supervision
For 1-12 years- 15 ml orally once with 1-2 glasses of water
Repeat with 15 ml once again if emesis doesn’t occur within 20-30 minutes
For more than 12 years- 15-30 ml orally once with 3-4 glasses of water
Repeat with 15 ml once again if emesis doesn’t occur within 20-30 minutes
Gastric lavage should be performed if vomiting doesn’t occur 30-45 minutes later the second dose
Intake of the syrup with 3-4 glasses of water
Not recommended for childhood poisoning now
Presently, the medication of choice is activated charcoal
For 6-12 months- 5-10 ml once with half or one cup of water under medical supervision
For 1-12 years- 15 ml orally once with 1-2 glasses of water
Repeat with 15 ml once again if emesis doesn’t occur within 20-30 minutes
For more than 12 years- 15-30 ml orally once with 3-4 glasses of water
Repeat with 15 ml once again if emesis doesn’t occur within 20-30 minutes
Gastric lavage should be performed if vomiting doesn’t occur 30-45 minutes later the second dose
Intake of the syrup with 3-4 glasses of water
Not recommended for childhood poisoning now
Presently, the medication of choice is activated charcoal
For 6-12 months- 5-10 ml once with half or one cup of water under medical supervision
For 1-12 years- 15 ml orally once with 1-2 glasses of water
Repeat with 15 ml once again if emesis doesn’t occur within 20-30 minutes
For more than 12 years- 15-30 ml orally once with 3-4 glasses of water
Repeat with 15 ml once again if emesis doesn’t occur within 20-30 minutes
Gastric lavage should be performed if vomiting doesn’t occur 30-45 minutes later the second dose
Intake of the syrup with 3-4 glasses of water
Refer to the adult dosing
Actions and Spectrum:
ipecac syrup is a medication used historically as an emetic, which induces vomiting. It is derived from the dried root of the ipecacuanha plant, which contains several alkaloids, including emetine and cephaeline. Here are some of the actions and the spectrum of ipecac syrup:
Frequency not defined
Aspiration
Prolonged vomiting
Mallory-Weiss tear
CNS depression
Pneumomediastinum
Therapy delay
Contraindication/Caution:
While ipecac syrup has been historically used as an emetic and for other purposes, there are several contraindications and precautions to consider before using it. Here are some of the most important:
Pregnancy consideration:
Category C
Breastfeeding warnings:
It is yet to be discovered if the drug is excreted in breast milk. Hence use cautiously.
Pregnancy category:
Pharmacology:
The pharmacology of ipecac involves its effects on the gastrointestinal and central nervous systems. Here are some of the pharmacological actions of ipecac:
Pharmacodynamics:
The pharmacodynamics of ipecac refer to how it exerts its effects on the body at the cellular and molecular levels. The main pharmacodynamic effect of ipecac is the induction of vomiting, primarily mediated through its effects on the central nervous system. Here are some of the pharmacodynamic actions of ipecac:
Pharmacokinetics:
Absorption
Produces effect 30 minutes after the ingestion
Significantly absorbed when emesis is not produced
Administration:
ipecac syrup is induces vomiting in cases of accidental ingestion of poisons or other toxic substances. It is typically administered orally, either directly or mixed with a liquid. Here are some general guidelines for the administration of ipecac syrup:
Patient information leaflet
Generic Name: ipecac syrup
Pronounced: ai-puh-kak si-ruhp
Why do we use ipecac syrup?
ipecac syrup is used in emergencies to induce vomiting in cases of accidental ingestion of poisons or other toxic substances. The goal of using ipecac syrup is to remove the toxic substance from the body. The use of ipecac syrup is typically reserved for cases in which the ingestion of the poison or toxin occurred within the last 30 minutes and when the poison control center or healthcare professional recommends its use.
ipecac syrup is considered a first-line treatment for certain types of poisoning, including:
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