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isoniazid

Brand Name :

Nydrazid

Synonyms :

Isoniazid

Class :

Hydrazide derivatives





No data available for drug.

Actions and spectrum:

It inactivates the growth of mycobacterium through mycolic acids production. Because of this action, INH has strong bactericidal properties and also works in concert with other species that KatG produces and other TB treatments.

DRUG INTERACTION

isoniazid

&

  • patisiran
  • imetelstat
  • phenylephrine ophthalmic
  • myoinositol
  • vasicinone
  • soda lime
  • fisetin
  • Reynoutria Japonica
  • Coco Monoethanolamide
  • Betadex
  • lithopone
  • cyperus rotundus
  • papaya juice
  • 1-naphthaleneacetic acid
  • Nordazepam
  • Glechoma hederacea
  • Alternanthera sessilis
  • nicofetamide
  • napthol asol
  • cocamidopropyl betaine
  • musa x paradisiaca
  • dicyclomine/mefenamic acid
  • Sorghum
  • Manganese citrate
  • tovorafenib
  • mefenamic acid/paracetamol
  • eschscholzia californica
  • canna indica root
  • tranexamic acid/mefenamic acid
  • dexverapamil
  • sitogluside
  • secalciferol
  • cefatrizine
  • Sedum Acre
  • Flurogestone
  • Fluocortin
  • Bifendate
  • piprozolin
  • aminacrine undecylate
  • ethylenediamine mandelate
  • pelubiprofen
  • hesperetin
  • butethamine
  • epitiostanol
  • androstenediol
  • Nitroxoline
  • Iocarmic acid
  • Capobenic acid
  • dordaviprone (investigational drug)
  • Vitexin
  • Friluglanstat (investigational drug)
  • scorias spongiosa
  • Luseogliflozin
  • indoxacarb
  • prademagene zamikeracel
  • fidanacogene elaparvovec-dzkt
  • albifylline
  • idanpramine
  • araneus diadematus
  • Sulfamazone
  • Lycosa tarantula
  • malotilate
  • Ethacizine
  • Namilumab
  • Latrunculin B
  • stachyose
  • platinic oxide
  • iopronic acid
  • calcium chloride / potassium chloride/lactic acid/ sodium chloride/sodium hydroxide/sodium lactate solution
  • citric acid/ sodium bicarbonate/ sodium carbonate anhydrous
  • vadadustat
  • permethrin medical grade cis/trans isomers 25/75
  • lutetium, isotope of mass 177
  • human normal immunoglobulin
  • sacrosidase
  • apadamtase alfa, recombinant
  • acetyl hexapeptide-8 amide
  • pemivibart (Investigational)
  • govorestat
  • Zanidatamab
  • sotatеrcеpt
  • MV 140 vaccine
  • leuprorelin implant
  • cinchocaine hydrochloride/fluocortolone hexanoate/fluocortolone pivalate
  • Beautyberry
  • risedronate/calcium/vitamin D3
  • rhubarb extract/senna leaf/sulphur purified/wood charcoal
  • boric acid/kaolin/methyl salicylate/peppermint oil/thymol
  • docosahexaenoic acid/eicospentaenoic acid
  • aluminium hydroxide/magnesium hydroxide/simethicone
  • gentamicin/hydrocortisone
  • succinylcholine
  • sinefungin
  • letibotulinumtoxinA
  • coal tar/coconut oil/salicylic acid
  • camphor/camphor oil white/capsicum oleoresin /menthol/methyl salicylate
  • thioglycolic acid
  • acetic acid auricular
  • roluperidone
  • hydrocortisone/crotamiton topical
  • nystatin/chlorhexidine
  • aluminium chloride hexahydrate
  • ketoprofen topical
  • Chlormethine
  • podophyllotoxin
  • urea/lactic acid
  • autologous chondrocytes implant
  • afelimomab
  • gepotidacin
  • fludroxycortide
  • fentanyl transdermal
  • erythromycin/zinc acetate
  • dibotermin alfa powder
  • desferrioxamine mesilate
  • choline salicylate/magnesium salicylate
  • castor oil/peru balsam/trypsin
  • betamethasone/dexchlorpheniramine maleate
  • benzalkonium chloride solution/cetrimide
  • barzolvolimab
  • ascorbic acid / calcium laevulinate / nicotinamide / calcium pantothenate / calcium chloride / riboflavine / pyridoxine hydrochloride / thiamine hydrochloride
  • argipressin
  • arachis oil refined/chlorobutanol hemihydrate
  • arachis oil/eucalyptol/nutmeg oil/terpineol
  • ammonium chloride/diphenhydramine hydrochloride/levomenthol
  • amino acid mixture d / calcium chloride dihydrate / glucose monohydrate / glycine / magnesium chloride hexahydrate / olive oil / potassium chloride / sodium acetate trihydrate / sodium glycerophosphate pentahydrate / soya-bean oil
  • biotin/colecalciferol/copper (ii)sulfate dried/ cyanocobalamine/ dl-alpha tocopherol acetate/dibasic calcium phosphate anhydrous/folic acid/iron (ii)sulfate dried/ lecithin/ magnesium sulfate dried/ nicotinamide/ pyridoxine hydrochloride/ riboflavin
  • ampicillin sodium / cloxacillin sodium
  • undecylenic acid, undecylenate salts, zincundecate
  • omeprazole/sodium bicarbonate
  • efgartigimod alfa/hyaluronidase
  • xylometazoline/ipratropium
  • cefepime and enmetazobactam
  • isotonic sodium chloride
  • bee venom allergen injection
  • fentanyl intranasal
  • alglucosidase alfa
  • triprolidine/pseudoephedrine
  • pegademase bovine
  • castor oil and peru balsam
  • camphor/eucalyptus oil/menthol
  • oxyquinoline/sodium lauryl sulfate
  • somatorelin
  • menotrophin injection
  • menadiol
  • hylan g-f 20
  • cefepime and taniborbactum
  • water avens
  • camphor/menthol
  • acoramidis
  • elafibranor
  • arrowroot
  • miconazole nitrate/hydrocortisone
  • vildagliptin/metformin
  • dobesilic acid
  • aroxybutynin and atomoxetine
  • hygromycin
  • linvoseltamab
  • nemolizumab
  • aceprometazine
  • limaprost
  • oxazolam
  • trimegestone
  • teceleukin
  • beauty berry
  • dinotefuran
  • imiprothrin
  • transfluthrin
  • thymalfasin
  • technetium Tc 99m tilmanocept
  • glepaglutide
  • marstacimab
  • pixantrone
  • Andiroba
  • arabinoxylan
  • arenaria rubra
  • etripamil
  • jequirity
  • jiaogulan
  • dusquetide
  • rolipram
  • tradipitant
  • sinfungin
  • diclofenac/omeprazole
  • brinzolamide and timolol maleate
  • wormseed
  • wormwood
  • wood sorrel
  • carmellose sodium
  • ibandronic acid
  • cinnarizine and dimenhydrinate
  • ursodeoxycholic acid
  • rhubarb extract/salicylic acid
  • butamirate citrate
  • fumitory
  • taheebo
  • uva ursi
  • vervain
  • coleus
  • coltsfoot
  • crampbark
  • plantain
  • potassium nitrate and silver nitrate
  • gelsemium
  • gentian
  • glucomannan
  • walnut
  • meadowsweet
  • midomafetamine
  • pennyroyal
  • periwinkle
  • betony
  • bitter orange
  • bladderwrack
  • bloodroot
  • emu oil
  • garcinia
  • yellow dock
  • burdock
  • dehydroepiandrosterone
  • aucubin
  • jasmone
  • resacetophenone
  • ecamsule ditriethanolamine
  • feclobuzone
  • fenoprop triethanolamine
  • verdyl acetate
  • caffeic acid
  • cyclamen aldehyde
  • dicetyldimonium chloride
  • wogonin
  • impacarzine
  • laurylpyridinium chloride
  • stepronin
  • matrine
  • sakuranin
  • cannabichromene
  • sandalore
  • sabinene
  • oxypaeoniflora
  • ethylhexyl pelargonate
  • acrylonitrile
  • allyl alcohol
  • dipalmitoylethyl hydroxyethylmonium methosulfate
  • butidrine
  • clothiapine
  • propanediol dicaprylate
  • buchu
  • undecanol
  • enilconazole
  • xymenynic acid
  • angelica
  • nizubaglustat
  • resomelagon
  • ulecaciclib
  • apple cider vinegar
  • bacopa
  • barley grass
  • dandelion
  • deer velvet
  • dolomite
  • bugleweed
  • bupleurum
  • glyceryltrinitrate
  • pociredir
  • asnuciclib
  • actalycabtagene autoleucel
  • butantan–dengue vaccine
  • travoprost/timolol
  • furosemide/potassium chloride
  • amylamine
  • jaborandi
  • patritumab deruxtecan
  • jackfruit
  • sterculia
  • ascorbigen
  • ashitaba
  • androstenetrione
  • andrachne
  • cosibelimab
  • racecadotril
  • neomycin/chlorhexidine
  • octocog alfa
  • cetrimide
  • ispaghula husk
  • polyhexanide
  • octenidine
  • polygeline
  • heparinoid
  • jewelweed
  • boldo
  • anizatrectinib
  • alpinia
  • henbane
  • cynanchum vincetoxicum root and sulfur
  • boditrectinib
  • izumerogant
  • zavondemstat
  • abuta
  • fadogia agrestis
  • fly agaric mushroom
  • meptazinol
  • methoxyflurane
  • tramadol/dexketoprofen
  • betaine/polyhexanide
  • filgotinib
  • inosine acedoben dimepranol
  • alverine citrate
  • hyoscine butylbromide
  • senna+ ispaghula
  • cabbage palm
  • cajeput oil
  • calanus oil
  • calamint
  • canada balsam
  • carnosine
  • alverine citrate/simeticone
  • dihydroartemisinin/piperaquine
  • mebeverine/ispaghula
  • calcipotriol
  • tacalcitol
  • triethyl citrate/ethyl linoleate
  • sodium dilauramidoglutamide lysine
  • fazamorexant
  • avibactam tomilopil and ceftibuten
  • drostanolone
  • tigilanol tiglate
  • isorhynchophylline
  • rhynchophylline
  • crisugabalin
  • epigallocatechin gallate
  • clomocycline
  • corynoxeine
  • isocorynoxeine
  • Culmerciclib
  • Neladenoson
  • ambrein
  • hexylcaine
  • phensuximide
  • resencatinib (investigational)
  • rolusafine
  • pumecitinib
  • arhalofenic acid
  • berdazimer sodium
  • benzquinamide
  • clidinium
  • sulfametopyrazine
  • fulzerasib (Investigational Drug)
  • rovadicitinib (Investigational Drug)
  • Upleganan (Investigational Drug)
  • menthyl ethylamido oxalate
  • quaternium-90 montmorillonite
  • unecritinib (investigational drug)
  • etohexadiol
  • guaiol
  • proximadiol
  • verdinexor
  • sofnobrutinib
  • talbutal
  • ethoxzolamide
  • propiomazine
  • enprofylline
  • phenmetrazine
  • merigolix
  • pralurbactam
  • neracorvir
  • vonifimod
  • apaziquone hydroquinone
  • darizmetinib
  • zandelisib
  • xininurad
  • ritivixibat
  • amiselimod phosphate (investigational drug)
  • emzeltrectinib (investigational drug)
  • ficonalkib
  • cinalukast
  • ulobetasol
  • candoxatril
  • nitrofural
  • acetyldigitoxin
  • bentiromide
  • dextrothyroxine
  • chlorotrianisene
  • remikiren
  • pipobroman
  • vidarabine
  • immune globulin intravenous, human-stwk
  • spermine
  • serine
  • N-acetyl glucosamine
  • valine
  • adenine
  • asparagine
  • citrulline
  • adinazolam
  • interferon alfacon-1
  • interferon alfa-n1
  • felypressin
  • birch triterpenes
  • pyridoxal phosphate
  • technetium Tc-99m arcitumomab
  • beta-alanine
  • dihomo-gamma-linolenic acid
  • urea/hydrocortisone
  • R21/Matrix-M vaccine
  • povidone-iodine (ophthalmic)
  • pheniramine
  • hydrocortisone rectal
  • chloroxylenol/pramoxine/zinc acetate
  • chloroxylenol/pramoxine
  • dextrose/sucrose/vitamin C/zinc sulphate
  • furazolidone/metronidazole/dicyclomine
  • ergocalciferol (vitamin D2)
  • benoxaprofen (discontinued)
  • teicoplanin
  • carbomer
  • chromic chloride / iron (ii) chloride tetrahydrate / potassium iodide / manganese chloride / sodium fluoride / sodium selenite pentahydrate / sodium molybdate dihydrate / zinc chloride/ cupric chloride
  • bufylline
  • lidocaine/prilocaine
  • opium tincture, squill oxymel
  • dibrompropamidine
  • metronidazole/tetracycline/bismuth subsalicylate
  • agnus- castus
  • velaglucerase alfa
  • alendronic acid / colecalciferol
  • bimatoprost / timolol
  • efbemalenograstim alfa
  • dried ferrous sulfate/folic acid
  • dried ferrous sulfate / sodium ascorbate
  • nirogacestat
  • soya-bean oil, medium-chain triglycerides
  • demeclocycline hydrochloride and triamcinolone acetonide
  • fusidic acid / hydrocortisone acetate
  • macrogol
  • storax, benzoin
  • nomegestrol acetate/estradiol
  • flumetasone pivalate/ clioquinol
  • berdazimer topical (Pending FDA Approval)
  • buflomedil
  • butobarbital
  • andexanet alfa
  • methoxypolyethylene glycol-epoetin beta
  • viscum abietis
  • pramoxine vaginal
  • bupivacaine implant
  • cromolyn sodium, inhaled
  • pneumococcal vaccine 20-valent
  • bimatoprost ophthalmic implant
  • tick-borne encephalitis vaccine
  • chloroprocaine ophthalmic
  • travoprost intraocular implant (Pending FDA approval)
  • typhoid polysaccharide vaccine
  • sodium phosphate rectal
  • human papillomavirus vaccine, nonavalent
  • peanut immunotherapy epicutaneous (FDA approval pending)
  • cromolyn sodium, intranasal
  • red blood cells(Blood component)
  • oral mucoadhesive
  • clindamycin vaginal
  • whole blood (Blood Component)
  • fibrinogen/thrombin
  • levothyroxine/liothyronine
  • ipratropium intranasal
  • metronidazole vaginal
  • cyamemazine
  • brinase
  • reviparin
  • ulinastatin
  • saruplase
  • acepromazine
  • emylcamate
  • methionine
  • amino acids and electrolytes in dextrose with calcium
  • slippery elm
  • camostat
  • hemoglobin crosfumaril
  • moperone
  • chlormidazole
  • brilaroxazine
  • palopegteriparatide
  • diazepam buccal
  • benegrastim (pending for FDA approval)
  • COVID-19 vaccine, adjuvanted-Novavax
  • vestronidase alfa-vjbk
  • tebipenem (Pending FDA Approval)
  • tislelizumab (Pending FDA Approval)
  • zolbetuximab (Pending FDA Approval)
  • zoliflodacin (pending FDA approval)
  • zibotentan and dapagliflozin
  • fluorine F18 DCFPyL
  • debamestrocel
  • givinostat
  • amubarvimab and romlusevimab(Pending FDA Approval)
  • sabizabulin(Pending FDA approval)
  • fexapotide(Phase 3 Clinical trial)
  • diatrizoic acid
  • drotaverine
  • diethyl phthalate
  • enclomiphene
  • epalrestat
  • ethamsylate
  • flupirtine
  • imidurea
  • sodium glycolate
  • feracrylum
  • ethacridine
  • furazolidone/metronidazole
  • ozagrel hydrochloride
  • leptazol
  • l-glutamic acid /vitamin B complex
  • etizolam
  • etizolam/propranolol
  • ethoheptazine citrate
  • etophylline and theophylline
  • etophylline
  • finger millet
  • drotaverine/mefenamic acid
  • dichloroxylenol
  • pneumococcal 7-valent vaccine
  • diclofenac and metaxalone
  • dipivefrin ophthalmic
  • enbucrilate
  • potassium citrate and citric acid
  • potassium gluconate
  • aclarubicin
  • alfuzosin/dutasteride
  • adrenochrome monosemicarbazone
  • selenium sulfide topical
  • sertaconazole
  • amorolfine cream
  • amsacrine
  • amylmetacresol
  • sulfonated phenolics in aqueous solution
  • technetium Tc-99m sulfur colloid
  • raltitrexed
  • romiplostim
  • acediasulfone
  • azulene
  • acebrophylline
  • clonazepam/escitalopram oxalate
  • allylestrenol
  • andrographolide
  • artemotil
  • technetium Tc-99m sestamibi
  • rubidium Rb-82
  • somapacitan
  • sodium sulfate, magnesium sulfate and potassium sulfate
  • almitrine
  • gramicidin
  • nikethamide
  • technetium Tc-99m sodium pertechnetate
  • betiatide
  • prilocaine/epinephrine
  • amlexanox
  • acetaminophen/salicylamide/phenyltoloxamine
  • neomycin topical
  • zilucoplan
  • antazoline and xylometazoline
  • toripalimab
  • iron isomaltoside
  • meningococcal A C Y and W polysaccharide tetanus toxoid conjugate vaccine
  • meningococcal A C Y and W-135 diphtheria conjugate vaccine
  • tetradecyl Sulfuric Acid
  • benzoyl peroxide, clindamycin phosphate, adapalene
  • ethylephedrine
  • actarit
  • pyrantel tartrate
  • tenofovir disoproxil fumarate or tenofovir DF
  • melitracen
  • amitriptylinoxide(Phase 4 Clinical Trials)
  • threonine
  • ditiocarb zinc
  • epicriptine
  • levallorphan
  • kinetin
  • laurocapram
  • pentagastrin
  • parthenolide
  • nicoboxil
  • protionamide
  • prulifloxacin
  • proscillaridin
  • tizanidine and rofecoxib
  • tolnaftate, gentamicin, chinoform and betamethasone valerate
  • pine bark extract
  • pipenzolate methylbromide
  • bephenium hydroxynaphthoate
  • niclosamide
  • pyrvinium
  • pipenzolate methylbromide/phenobarbitone
  • piracetam/ginkgo biloba/vinpocetine
  • benzyl benzoate/disulfiram
  • benzyl benzoate
  • loperamide/simethicone
  • piroctone olamine
  • sodium fusidate
  • piroxicam topical/capsaicin/menthol/methyl salicylate
  • sodium metabisulfite
  • sodium lauryl sulfate
  • taspoglutide
  • glyclopyramide
  • tolnaftate, gentamicin, iodochlorohydroxyquinoline, chlorocresol, betamethasone valerate
  • serratiopeptidase
  • sodium antimony gluconate
  • triamterene / benzthiazide
  • tribenoside / lidocaine
  • triclocarban
  • triprolidine/dextromethorphan  
  • vitamins/minerals/omega-3 Fatty acids
  • soyabean oil
  • sucralfate/oxethazaine
  • sucralfate/tinidazole/povidone iodine
  • sodium cromoglycate
  • aloe vera/liquid paraffin/white soft paraffin
  • aloe vera/jojoba oil/vitamin E
  • allantoin/triclosan/vitamin e/zinc oxide
  • alpha-Lipoic acid/minerals/multivitamins
  • alprazolam/paracetamol
  • alprazolam/melatonin
  • azithromycin/ambroxol
  • atorvastatin/clopidogrel/aspirin
  • aceclofenac, paracetamol and serratiopeptidase
  • alfacalcidol, vitamin B-complex, minerals and antioxidants
  • alpha- lipoic acid, vitamin b complex and vitamin c
  • alpha-galactosidase and simethicone
  • alpha-galactosidase, amylase, proteases, lipase and lactase
  • amikacin and cefepime
  • aminophylline, ephedrine and phenobarbitone
  • artesunate, sulphadoxine and pyrimethamine
  • finasteride/tamsulosin
  • flavoxate/ofloxacin
  • fenofibrate/metformin
  • lignocaine, hydrocortisone topical and allantoin
  • linoleic acid and sodium lactate
  • troxerutin
  • meclizine/nicotinic acid
  • mecobalamin/ginkgo Biloba
  • spirulina
  • loperamide and furazolidone
  • ketoconazole/cetrimide
  • ketoconazole/zinc pyrithione
  • lercanidipine/atenolol
  • levocetirizine/montelukast/ambroxol
  • levarterenol
  • levocetirizine/phenylpropanolamine 
  • indapamide/amlodipine
  • itopride/methyl polysiloxane
  • mebendazole/levamisole
  • eberconazole/mometasone
  • gliclazide/metformin/pioglitazone
  • fluconazole/tinidazole
  • haemocoagulase
  • halometasone
  • hesperidin
  • imipramine/chlordiazepoxide
  • idebenone / l-arginine / zinc sulphate/selenium/proanthocyanidin
  • mecobalamin and piracetam
  • mesterolone
  • mosapride and pantoprazole
  • atorvastatin, co enzyme q10, vitamin e, zinc, and selenium
  • azithromycin and benzalkonium chloride
  • beta carotene, vitamin c, vitamin e, minerals, lutein, eicosapentaenoic acid, docosahexenoic acid and vit b12
  • alpha-galactosidase
  • aloe vera gel/vitamin e/lactic acid
  • aloe vera gel/jojoba/vitamin e/glycerine
  • famotidine and domperidone
  • faropenem medoxomil
  • nedosiran
  • fluconazole/ornidazole/azithromycin
  • ebastine/montelukast
  • eberconazole
  • dienogest/estradiol valerate
  • ambroxol/salbutamol
  • benzoic acid/salicylic acid/ichthammol/ triamcinolone acetonide
  • desloratadine/ambroxol
  • dexibuprofen/paracetamol
  • atorvastatin/ramipril
  • diastase
  • diastase and simethicone
  • diazepam and propranolol
  • dexrabeprazole / domperidone
  • dexrabeprazole
  • dexketoprofen /paracetamol
  • beta carotene/vitamin C/minerals
  • aloe vera gel/urea
  • aloe vera gel/glycerine
  • alpha-lipoic acid/benfotiamine/chromium/folic acid/mecobalamin / vit b6
  • alprazolam/propranolol
  • alprazolam /sertraline
  • ibuprofen/dextropropoxyphene
  • ambroxol/cetirizine/phenylephrine/ guaiphenesin/menthol
  • dextropropoxyphene/dexchlorpheniramine maleate/bromhexine
  • promegestone
  • batroxobin
  • bencyclane
  • benfluorex
  • acetylpheneturide
  • abarelix
  • abetimus
  • naftidrofuryl
  • nalorphine
  • oxiracetam
  • letosteine
  • lafutidine
  • leuprorelin
  • levodropropizine
  • glutaral
  • losartan/ramipril
  • gallopamil
  • lanatoside c
  • lauromacrogol
  • gestodene
  • aceclofenac/methyl salicylate/menthol/linseed oil/capsaicin
  • aceclofenac/paracetamol/tizanidine
  • alginic acid/magaldrate/simethicone
  • aceclofenac/paracetamol
  • aceclofenac/rabeprazole
  • alginic acid
  • pantoprazole and domperidone
  • urokinase
  • rimiterol
  • olanzapine/fluoxetine
  • normethadone/hydroxyephedrine
  • myrtol
  • moxonidine
  • propylhexedrine
  • sodium hypochlorite solution
  • sodium chloride/sodium citrate
  • Hepatitis B Vaccine (Recombinant [Adjuvanted])
  • Hepatitis B Vaccine (Recombinant)
  • aceclofenac and serratiopeptidase
  • levosulpiride
  • niaprazine
  • tromantadine
  • trimetazidine
  • vinburnine
  • mizoribine
  • molgramostim
  • mosapride
  • eugenol
  • tolperisone
  • etamsylate
  • etynodiol
  • mizolastine
  • metenolone
  • reproterol
  • rebamipide
  • mephenoxalone
  • metandienone
  • furosemide/spironolactone
  • hydroxycarbamide
  • tenonitrozole
  • fenoverine
  • fenquizone
  • tiapride
  • tibolone
  • furazolidone
  • furosemide & amiloride
  • fosfestrol
  • fluclorolone
  • flubendazole
  • tertatolol
  • tetracosactide
  • tetryzoline
  • tolciclate
  • trapidil
  • troxipide
  • temoporfin
  • telbivudine
  • teprenone
  • hexamidine
  • mebhydrolin
  • mepartricin
  • fencamfamin
  • medazepam
  • theodrenaline
  • thiamazole
  • thiocolchicoside
  • psilocybin
  • veralipride
  • pyritinol
  • opipramol
  • oprelvekin
  • betamethasone + gentamicin
  • betamethasone + neomycin
  • betamethasone + salicylic acid
  • oxedrine
  • bopindolol
  • orgotein (investigational)
  • oxaceprol
  • ormeloxifene
  • bevantolol
  • bifemelane
  • clebopride
  • demoxytocin
  • cicletanine
  • cefsulodin
  • chlortalidon
  • sisomicin
  • somatrem
  • carbazochrome
  • caroverine
  • cathine
  • ipriflavone
  • isepamicin
  • silymarin
  • simethicone
  • sermorelin
  • diloxanide
  • dimethindene
  • diosmin/hesperidin
  • calamine
  • canrenone
  • captodiame
  • imidapril
  • cefetamet
  • cefodizime
  • cefoperazone + sulbactam
  • ivermectin + albendazole
  • serrapeptase
  • bromisoval
  • beraprost
  • pridinol
  • proglumide
  • bamipine
  • barnidipine
  • bamifylline
  • benzbromarone
  • betamethasone/fusidic acid
  • para-chlorophenol
  • pantethine
  • nomifensine
  • pemoline
  • parnaparin
  • pentolinium
  • nialamide
  • novobiocin
  • nicergoline
  • octocrylene
  • octisalate
  • oftasceine
  • oxolamine
  • oxyphencyclimine
  • penfluridol
  • pentoxyverine
  • phenoxymethylpenicillin
  • picloxydine
  • pilsicainide hydrochloride
  • piperazine
  • pirarubicin
  • policresulen
  • prifinium bromide
  • prethcamide
  • pristinamycin
  • pirenzepine
  • piribedil
  • pimethixene
  • pargyline
  • phosphatidyl choline
  • phthalylsulfathiazole
  • phytomenadione
  • pranlukast
  • pinazepam
  • oxyphenonium
  • noxytiolin
  • periciazine
  • pethidine
  • phenindamine
  • histidine
  • isoleucine
  • proline
  • lauric acid
  • lymecycline
  • hypromellose
  • abiraterone acetate and niraparib
  • ichthammol
  • levamisole
  • naftazone
  • nefopam
  • oxprenolol
  • oxybuprocaine
  • elranatamab-bcmm
  • lapyrium
  • isoaminile
  • iotrolan
  • mazindol
  • masoprocol
  • lypressin
  • meradimate
  • molsidomine
  • monobenzone
  • mequinol/gluconolactone/ lactobionic acid/ arbutin
  • medifoxamine
  • mebutamate
  • metergoline
  • methantheline
  • methdilazine
  • metocurine
  • micronomicin
  • metaraminol
  • mephenesin
  • menadione
  • medrysone
  • metixene
  • levobetaxolol
  • guaiacol glycerol ether
  • eucalyptol
  • sodium tetradecyl sulfate
  • sugammadex
  • carbetocin
  • certoparin
  • chlorcyclizine/pseudoephedrine
  • cephapirin
  • indecainide
  • iobitridol
  • iomeprol
  • chlorphenesin
  • msud analog
  • msud maxamum
  • iceland moss
  • glutethimide
  • hexachlorophene
  • haloprogin
  • deferoxamine
  • ethchlorvynol
  • dexpanthenol topical
  • etilefrine
  • deslanoside
  • carbocromen
  • diazolidinylurea
  • dibenzepin
  • etofamide
  • guanoxan
  • halazepam
  • guanadrel sulfate
  • dapiprazole
  • soapwort
  • debrisoquine
  • l-tryptophan
  • chlormerodrin
  • chlorquinaldol
  • cetrimonium
  • carbocisteine
  • chlorcyclizine/codeine
  • technetium Tc-99m tetrofosmin
  • technetium Tc-99m disofenin
  • technetium Tc-99m gluceptate
  • technetium Tc-99m labeled red blood cells
  • amylmetacresol/dextromethorphan hydrobromide
  • anileridine phosphate
  • pyrethrins
  • pyrantel pamoate
  • quinagolide
  • spiramycin
  • standard hyperkalemic cardioplegia solution
  • technetium tc-99m mertiatide
  • technetium tc-99m medronate
  • bemotrizinol / bisoctrizole
  • benfotiamine
  • bemotrizinol + titanium dioxide + zinc oxide
  • technetium Tc-99m oxidronate
  • technetium Tc-99m pentetate
  • technetium Tc-99m pyrophosphate
  • benziodarone
  • octinoxate/bisoctrizole
  • bicisate dihydrochloride
  • technetium Tc-99m bicisate
  • norelgestromin/ethinyl estradiol
  • norgestimate/ethinyl estradiol
  • ximelagatran (investigational)
  • xamoterol
  • trioxsalen
  • poly-urea urethane
  • rilmenidine
  • pemirolast
  • oxitriptan
  • beclomethasone, intranasal
  • thimerosal
  • camphor gel
  • camphor
  • mumps virus vaccine, live
  • rubella virus vaccine, live
  • aluminum chloride (dental)
  • alum irrigation
  • framycetin, phenylephrine, and gramicidin
  • ombitasvir, paritaprevir, ritonavir, and dasabuvir
  • olipudase alfa
  • etonogestrel/ethinyl estradiol
  • mycophenolate
  • fluoroestradiol F 18
  • donor organ cardioplegia solution
  • fluciclovine F 18
  • fusidic acid (ophthalmic)
  • fusidic acid and hydrocortisone
  • framycetin, dexamethasone, and gramicidin
  • fludeoxyglucose F-18
  • fluorouracil/salicylic acid
  • indium In-111 oxyquinoline
  • indium In-111 pentetreotide
  • indium In-111 capromab pendetide
  • lusutrombopag
  • mitomycin (ophthalmic)
  • mifepristone and misoprostol
  • minoxidil (systemic)
  • methyl aminolevulinate (topical)
  • methyl folate, methylcobalamin, and acetylcysteine
  • ciclesonide/formoterol/tiotropium
  • nedocromil (Oral Inhalation)
  • batefenterol (Investigational)
  • neostigmine and glycopyrrolate
  • nepafenac ophthalmic
  • netupitant/palonosetron
  • meperidine and promethazine
  • mepivacaine and levonordefrin
  • maltodextrin
  • medical cannabis
  • medium chain triglycerides
  • mometasone/glycopyrrolate (glycopyrronium)/ indacaterol
  • moxifloxacin ophthalmic
  • neomycin/fluocinolone
  • nadroparin
  • iodine I-125 iothalamate
  • amikacin liposome (oral inhalation)
  • bupivacaine liposome
  • natamycin
  • lopinavir and ritonavir
  • lysine
  • macitentan and tadalafil
  • mitomycin pyelocalyceal
  • moclobemide
  • mometasone and indacaterol
  • efinaconazole
  • blue-green algae
  • indocyanine green
  • follitropin beta
  • lumasiran
  • glycerin/lidocaine
  • edrophonium/atropine
  • indigo carmine
  • lutropin alfa
  • instant glucose/intravenous dextrose
  • iobenguane I-123
  • ixekizumab
  • isosulfan blue dye
  • levofloxacin ophthalmic
  • levonorgestrel oral/ferrous bisglycinate/ ethinylestradiol
  • ethinyl estradiol/levonorgestrel transdermal
  • hydroquinone
  • hydroxypropyl methylcellulose
  • icodextrin
  • lipid emulsion (soybean, medium-chain triglyceride, olive, and fish oils; [SMOF])
  • iodinated I 125 albumin
  • iodinated I 131 albumin
  • lipid emulsion (plant oil-based)
  • levonorgestrel intrauterine
  • levonorgestrel/ethinyl estradiol
  • lactic acid and sodium-PCA
  • lactated Ringer solution
  • ketotifen (systemic)
  • lanolin
  • leuprolide and norethindrone
  • levodopa and benserazide
  • gonadorelin acetate
  • hemodialysis solutions
  • nirsevimab
  • gentian violet
  • gallium ga-68 dotatate
  • fusidic acid and betamethasone
  • gallium citrate Ga-67
  • gadopentetate dimeglumine
  • gadofosveset
  • follitropin delta
  • follitropin alfa and lutropin alfa
  • follitropin alfa
  • rocatinlimab
  • grass pollens allergen extract
  • flotufolastat F18
  • fluorescein ophthalmic
  • barium
  • balanced salt solution
  • air polymer type A intrauterine device
  • clodronate
  • bentoquatam
  • clobetasone
  • alfacalcidol
  • citric acid/glucono-delta-lactone/magnesium carbonate
  • benzoin
  • desirudin
  • immune globulin IV (IGIV)
  • dequalinium
  • pseudoephedrine/desloratadine
  • clofedanol
  • cyproterone and ethinyl estradiol
  • dextranomer and hyaluronic acid or derivatives
  • diatrizoate meglumine and diatrizoate sodium
  • glucosamine sulfate, chondroitin sulfate and Msm
  • squill
  • gotu kola
  • blessed thistle
  • bitter melon
  • apraclonidine
  • chlophedianol/dexbrompheniramine/pseudoephedrine
  • wild jujube
  • chitosan
  • cilazapril/hydrochlorothiazide
  • dexbrompheniramine and phenylephrine
  • diethylene triamine penta-acetic acid
  • dexchlorpheniramine and pseudoephedrine
  • lily of the valley
  • diflucortolone
  • corydalis
  • lemon balm
  • MSM
  • calcium polystyrene sulfonate
  • caprylidene
  • peppermint oil
  • efavirenz/lamivudine/tenofovir DF
  • emtricitabine/tenofovir DF /efavirenz
  • dutasteride/tamsulosin
  • milk thistle
  • centaury
  • horseweed
  • lycopus
  • agrimony
  • alfalfa
  • kava
  • cetrorelix
  • cetylpyridinium
  • chlophedianol and dexbrompheniramine
  • betahistine
  • choline C-11
  • boric acid vaginal suppository
  • aluminum acetate
  • aluminum chloride hexahydrate
  • 14-C urea breath test
  • absorbable collagen
  • valoctocogene roxaparvovec-rvox
  • amlodipine and celecoxib
  • aspirin and omeprazole
  • azilsartan and chlorthalidone
  • landiolol (Pending FDA approval)
  • isosorbide dinitrate/hydralazine
  • losartan/hydrochorothiazide
  • udenafil
  • dextromethorphan/quinidine
  • onasemnogene abeparvovec
  • orphenadrine/aspirin/caffeine
  • trace elements
  • sodium phenylbutyrate/ taurursodiol
  • fish oil triglycerides
  • infant formula
  • glutamine
  • chloroquine phosphate
  • afatinib
  • quinidine gluconate
  • methylergonovine
  • prothrombin complex concentrate, human
  • BCG intravesical live
  • capivasertib
  • cedazuridine
  • carbonyl iron
  • iron dextran complex
  • lovotibeglogene autotemcel (FDA Approval Pending)
  • sodium benzoate/sodium phenylacetate
  • mineral oil otic
  • zolmitriptan transdermal
  • midazolam intranasal
  • fosinopril/hydrochlorothiazide
  • caplacizumab
  • arginine
  • sodium phenylbutyrate
  • meloxicam/rizatriptan
  • manganese
  • acetaminophen/pamabrom/pyridoxine
  • varicella zoster immune globulin, human
  • amitriptyline/perphenazine
  • narsoplimab (Pending FDA Approval)
  • amlodipine/perindopril
  • imiglucerase
  • canagliflozin/metformin
  • tafamidis meglumine
  • somatrogon-ghla
  • glimepiride/rosiglitazone
  • becaplermin
  • lithium
  • loxapine inhaled
  • nicotine transdermal
  • tixagevimab and cilgavimab (Investigational)
  • muromonab CD3
  • ansuvimab
  • coal tar bath products
  • fibrin sealant
  • arimoclomol (FDA Approval Pending)
  • varenicline intranasal
  • aducanumab
  • oxycodone/naloxone
  • ritlecitinib
  • sodium polystyrene sulfonate
  • calcipotriene/betamethasone
  • calcium hydroxylapatite
  • cantharidin topical
  • doxepin cream
  • clocortolone
  • formaldehyde topical
  • sodium sulfide topical
  • collagenase
  • selegiline transdermal
  • foscarbidopa/foslevodopa (FDA approval pending)
  • saxagliptin/metformin
  • linagliptin/metformin
  • linzagolix (FDA approval pending)
  • efgartigimod/hyaluronidase SC
  • elamipretide (Pending FDA approval)
  • rozanolixizumab
  • diazoxide
  • glimepiride/pioglitazone
  • cipaglucosidase alfa
  • dihydroergotamine intranasal
  • delandistrogene moxeparvovec
  • beremagene geperpavec
  • hyaluronic acid and derivatives
  • hyaluronic acid, non-animal stabilized
  • eplontersen (FDA Approval Pending)
  • nitric oxide gas
  • sodium phenylbutyrate and taurursodiol
  • treprostinil SC
  • viltolarsen
  • albuterol/ipratropium
  • budesonide inhaled
  • budesonide rectal
  • palovarotene
  • sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycol
  • amino acids mixture
  • aminobenzoate potassium
  • elivaldogene autotemcel
  • naproxen and sumatriptan
  • sumatriptan intranasal
  • alglucerase
  • metformin/rosiglitazone
  • ertugliflozin/metformin
  • elosulfase alfa
  • calcium carbonate/magnesium hydroxide
  • starch suppository
  • abicipar pegol (FDA Approval Pending)
  • riboflavin 5′-phosphate ophthalmic
  • povidone ophthalmic
  • glycerin oropharyngeal
  • dimethicone topical
  • menthol topical, dimethicone topical
  • pramoxine topical, menthol topical and dimethicone topical
  • phosphorated carbohydrate
  • brilliant blue G ophthalmic
  • brolucizumab intravitreal
  • purified water, ophthalmic
  • hydroxyethyl cellulose ophthalmic
  • ranibizumab intravitreal implant
  • sodium chloride hypertonic, ophthalmic 
  • cetirizine ophthalmic
  • phentolamine ophthalmic
  • ganciclovir ophthalmic
  • triamcinolone intravitreal
  • ocriplasmin intravitreal
  • atoltivimab/maftivimab/odesivimab
  • pegcetacoplan intravitreal
  • triamcinolone acetonide extended-release injectable suspension
  • tobramycin/loteprednol ophthalmic
  • 2-octyl cyanoacrylate
  • vitamins A & D topical
  • diphenhydramine/allantoin topical
  • pyrethrins/piperonyl butoxide
  • lodoxamide ophthalmic
  • obeticholic acid
  • fluocinolone intravitreal implant
  • sincalide
  • linaclotide
  • nedocromil ophthalmic
  • cysteamine ophthalmic
  • avacincaptad pegol intravitreal
  • azelastine ophthalmic
  • bacitracin ophthalmic
  • propylene glycol ophthalmic
  • rimexolone ophthalmic
  • metoclopramide intranasal
  • mirikizumab
  • netarsudil ophthalmic
  • cenegermin
  • dexamethasone ophthalmic insert
  • prednisolone ophthalmic
  • phenylephrine and cocoa butter rectal
  • phenylephrine and witch hazel topical
  • phenylephrine, pramoxine, glycerin and petrolatum rectal
  • bisacodyl rectal
  • aluminum hydroxide/magnesium carbonate
  • aluminum hydroxide/magnesium hydroxide
  • hyoscyamine spray
  • methenamine/methylene blue/ hyoscyamine/ sodium phosphate monobasic/ phenyl salicylate
  • phenylephrine
  • chlorophyll
  • castor oil
  • cholic acid
  • phenol oropharyngeal
  • articaine/epinephrine
  • antithymocyte globulin equine
  • aluminum hydroxide/magnesium trisilicate
  • methenamine/hyoscyamine
  • hydrocortisone topical/pramoxine topical 
  • sodium fluoride topical
  • mesna
  • C1 esterase inhibitor recombinant
  • menthol and pectin
  • menthol oropharyngeal
  • pectin oropharyngeal
  • gepirone
  • Goldenseal
  • polyethylene glycol and electrolytes
  • polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid
  • brompheniramine/pseudoephedrine/dextromethorphan
  • brompheniramine phenylephrine
  • acetaminophen/doxylamine/phenylephrine
  • doxylamine/acetaminophen/pseudoephedrine/dextromethorphan
  • acetaminophen/doxylamine/dextromethorphan
  • acetaminophen/doxylamine/dextromethorphan/phenylephrine
  • eslicarbazepine
  • fluticasone and salmeterol
  • codeine, acetaminophen, butalbital and caffeine
  • codeine, chlorpheniramine and phenylephrine
  • iodine
  • povidone iodine
  • butalbital/aspirin/caffeine/codeine
  • polyethylene glycol 400/propylene glycol ophthalmic 
  • pegvaliase
  • amivantamab
  • iopamidol
  • codeine and pseudoephedrine
  • emtricitabine, rilpivirine, tenofovir DF
  • penicillin G aqueous
  • miconazole topical
  • miconazole vaginal
  • ciprofloxacin inhaled (Pending FDA approval)
  • ceftazidime/avibactam
  • ceftolozane/​tazobactam
  • aztreonam inhalation
  • amphotericin B cholesteryl sulfate
  • miconazole oral
  • elvitegravir/cobicistat/emtricitabine/tenofovir DF
  • isavuconazonium sulfate
  • dapivirine intravaginal (FDA Approval Pending)
  • lamivudine/raltegravir
  • codeine/triprolidine/pseudoephedrine
  • cadexomer iodine
  • brompheniramine/pseudoephedrine
  • codeine/acetaminophen
  • codeine/guaifenesin
  • beclomethasone inhaled
  • epoetin beta/methoxy polyethylene glycol
  • voreloxin(Orphan Drug)
  • rociletinib
  • pitcher plant
  • phosphatidylserine
  • telotristat ethyl
  • copper CU 64 dotatate
  • urea topical
  • exenatide subdermal implant
  • asenapine transdermal
  • ethiodized oil
  • urea oral
  • miglustat
  • acalisib(Investigational)
  • acetophenazine
  • guggul
  • aceneuramic acid
  • mestranol/norethindrone
  • reishi
  • lactitol
  • vonoprazan fumarate
  • motherwort
  • silver nitrate
  • salicylic acid/sulfur shampoo
  • salicylic acid topical
  • ketorolac ophthalmic
  • ketoconazole topical
  • Japanese encephalitis virus vaccine
  • dibucaine topical ointment
  • ketorolac intranasal
  • ketorolac/phenylephrine ophthalmic
  • rotavirus oral vaccine, live
  • guarana
  • hops
  • krill oil
  • salicylic acid/coal tar shampoo
  • sufentanil SL
  • pancrelipase
  • passion flower
  • pepdite one plus
  • nivolumab and relatlimab
  • relatlimab (Pending FDA Approval)
  • benzalkonium chloride/benzocaine
  • ketotifen, drug-eluting contact lens
  • calcitriol topical
  • oxymetazoline topical
  • alclometasone topical
  • capsaicin topical
  • diclofenac/misoprostol
  • diclofenac ophthalmic
  • diclofenac topical
  • pramoxine/calamine topical
  • veverimer
  • tolazoline
  • olopatadine ophthalmic
  • lutetium lu 177-dota-tate
  • lutetium lu 177 vipivotide tetraxetan
  • strontium 89 chloride
  • interferon alfa n3
  • lutetium Lu 177- Diethylenetriamine Pentaacetic acid-omburtamab (FDA Approval Pending)
  • samarium sm 153 lexidronam
  • cytomegalovirus immune globulin (CMV IG)
  • antithymocyte globulin rabbit
  • inolimomab (Pending FDA Approval)
  • olopatadine intranasal
  • olopatadine intranasal/​mometasone, intranasal
  • benzocaine/butamben/tetracaine topical
  • antipyrine/benzocaine/phenylephrine
  • dyclonine/menthol
  • surufatinib
  • fruquintinib
  • dostarlimab
  • hepatitis B immune globulin (HBIG)
  • remestemcel-L
  • benzocaine/menthol oropharyngeal
  • interferon beta 1b
  • tetracaine/oxymetazoline intranasal
  • benzocaine oropharyngeal
  • benzalkonium chloride/menthol/petrolatum topical
  • inamrinone
  • alpha 1 proteinase inhibitor
  • potassium bicarbonate/potassium citrate
  • potassium phosphate/sodium acid phosphate
  • asparaginase Erwinia chrysanthemi recombinant
  • motixafortide
  • pegloticase
  • etesevimab
  • Rho(D) immune globulin
  • tetanus immune globulin (TIG)
  • reltecimod (pending FDA approval)
  • avasopasem
  • trimethoprim/polymyxin B ophthalmic
  • naphazoline ophthalmic
  • sulfacetamide topical
  • sirolimus intravitreal (pending FDA approval)
  • sirolimus protein bound
  • sirolimus topical
  • glycopyrronium tosylate topical
  • sofpironium
  • olmesartan, amlodipine and hydrochlorothiazide
  • dovitinib (Pending FDA Approval)
  • epinephrine inhaled
  • quizartinib (Pending FDA Approval)
  • ranibizumab intravitreal injection
  • sodium hyaluronate
  • bacitracin and lidocaine topical
  • brimonidine topical
  • benzoyl peroxide and tretinoin topical
  • talquetamab
  • betrixaban
  • acetaminophen/caffeine/pyrilamine
  • fentanyl transmucosal
  • bacitracin topical
  • buprenorphine,long-acting injection
  • buprenorphine buccal
  • nalmefene intranasal
  • sulbactam/durlobactam
  • metronidazole topical 
  • daratumumab/hyaluronidase
  • glofitamab
  • rituximab-hyaluronidase
  • drospirenone/ethinyl estradiol/levomefolate
  • loncastuximab tesirine
  • ingenol mebutate topical
  • momelotinib
  • trastuzumab/deruxtecan
  • trastuzumab/hyaluronidase
  • trastuzumab duocarmazine
  • lifileucel
  • umbralisib
  • eflornithine/sulindac
  • cytarabine/daunorubicin liposomal
  • doxorubicin liposomal
  • epcoritamab
  • lanadelumab  
  • esomeprazole/naproxen 
  • terbinafine topical
  • ravulizumab
  • clotrimazole topical
  • choline magnesium trisalicylate
  • tacrolimus ointment
  • mechlorethamine topical
  • donislecel
  • pozelimab (Pending FDA Approval)
  • human rabies immune globulin (HRIG)
  • melphalan flufenamide
  • sintilimab (Pending FDA Approval)
  • oportuzumab monatox (Pending FDA Approval)
  • sotorasib
  • irinotecan liposomal
  • sulfur topical
  • silver sulfadiazine
  • capsaicin transdermal
  • sutimlimab
  • tretinoin topical
  • acetaminophen rectal
  • menthol topical
  • naftifine
  • oatmeal, colloidal topical
  • oxiconazole
  • methylsalicylate/menthol topical
  • C1 inhibitor human
  • lifitegrast ophthalmic
  • prednisolone/sulfacetamide ophthalmic
  • mannitol inhalation
  • ofloxacin otic
  • petrolatum & mineral oil topical
  • clascoterone topical
  • gefapixant (Pending FDA Approval)
  • colesevelam
  • technetium Tc 99m succimer
  • nebivolol/valsartan
  • ciprofloxacin/fluocinolone acetonide, otic
  • finafloxacin otic
  • magnesium hydroxide/mineral oil
  • phenylephrine/mineral oil/petrolatum rectal
  • carbamide peroxide oral
  • atropine ophthalmic
  • sodium sulfacetamide/sulfur
  • sulfacetamide ophthalmic
  • lucinactant
  • benzonatate
  • besifloxacin ophthalmic
  • benzhydrocodone/acetaminophen
  • beractant
  • trimagnesium citrate anhydrous
  • vitamin b2
  • carbamide peroxide otic
  • mineral oil topical
  • ethyl alcohol intranasal
  • boric acid/alcohol otic
  • absorbable gelatin compressed sponge, USP
  • absorbable gelatin sponge, USP
  • vincristine liposomal
  • technetium Tc 99m albumin aggregated injection
  • metaproterenol
  • budesonide inhaled/formoterol/glycopyrrolate inhaled
  • epinephrine racemic
  • umeclidinium bromide/vilanterol inhaled
  • indacaterol, inhaled/glycopyrrolate inhaled
  • betaine  
  • laronidase 
  • estrogens esterified/methyltestosterone            
  • cerliponase alfa
  • ertugliflozin/sitagliptin
  • hawthorn
  • shepherd’s purse
  • thiamine
  • naphazoline/glycerin ophthalmic
  • oxymetazoline ophthalmic
  • dorzolamide
  • dexamethasone intraocular
  • dexamethasone/ciprofloxacin
  • dexamethasone ophthalmic
  • metipranolol ophthalmic
  • timolol ophthalmic
  • boron
  • fezolinetant
  • pegunigalsidase alfa-iwxj
  • biotin
  • pantothenic acid
  • silicon
  • sodium acid phosphate
  • hypochlorous acid topical
  • methenamine/sodium acid phosphate
  • aviptadil 
  • bremelanotide
  • glucagon intranasal
  • metformin and repaglinide
  • bai ji
  • pau d’arco
  • juzentaihoto
  • mistletoe
  • quercetin
  • rosemary
  • sheng di huang
  • chasteberry
  • maitake
  • grapefruit
  • lentinan
  • juniper
  • nettle
  • parsley
  • rose hips
  • tongkat ali
  • horny goat weed
  • damiana
  • yohimbe
  • insulin NPH
  • aprocitentan
  • noni Juice
  • sodium iodide I-131
  • green tea
  • sea cucumber
  • wheat germ extract
  • fenofibrate micronized 
  • rogisen
  • danshen
  • lutein
  • witch hazel
  • dextroamphetamine transdermal
  • amphetamine/dextroamphetamine
  • hoodia
  • kolanut
  • boswellia
  • opuntia ficus indica
  • lavender
  • nadh
  • tea tree oil
  • metformin/sitagliptin 
  • dapagliflozin/ metformin/saxagliptin  
  • antihemophilic factor recombinant
  • inclisiran
  • bempedoic acid/ezetimibe
  • volanesorsen  
  • omega 3 carboxylic acids
  • pericyazine
  • levomepromazine (methotrimeprazine)
  • betaxolol ophthalmic
  • respiratory syncytial virus vaccine, adjuvanted
  • phenylephrine hydrochloride and tropicamide ophthalmic
  • alirocumab
  • neomycin/polymyxin B/gramicidin ophthalmic
  • factor IX
  • gentamicin topical
  • ansofaxine (Pending FDA Approval)
  • zuranolone
  • factor IX, recombinant
  • factor IX complex
  • factor XIII A-subunit, recombinant
  • factor X, human
  • mesalamine rectal
  • etrasimod
  • anti-inhibitor coagulant complex
  • factor IX, recombinant/albumin fusion protein
  • fibrinogen, human
  • aminocaproic acid
  • metyrosine
  • nonoxynol-9 vaginal
  • progesterone intravaginal gel
  • ipecac syrup
  • botulinum antitoxin, heptavalent
  • pentetate calcium trisodium
  • crotalidae polyvalent immune FAB (ovine)
  • dehydrated alcohol injection 
  • gold sodium thiomalate (Discontinued)
  • lactic acid/citric acid/potassium bitartrate vaginal
  • von Willebrand factor, recombinant
  • luspatercept
  • digoxin immune FAB (Antidote)
  • crotalidae immune FAB (equine)
  • magnesium (Antidote)
  • pyridoxine (Antidote)
  • edetate calcium disodium
  • albumin IV
  • nitroglycerin sublingual
  • obiltoxaximab
  • anthrax immune globulin
  • nitroglycerin topical
  • dextrose
  • nesiritide
  • estradiol vaginal
  • bazedoxifene/conjugated estrogens
  • botulism immune globulin iv
  • amoxicillin/omeprazole/rifabutin
  • synthetic human angiotensin II
  • nitroglycerin IV
  • nitroglycerin translingual
  • nitroprusside sodium
  • tetrahydrozoline/zinc sulfate/hypromellose ophthalmic
  • sodium citrate/citric acid
  • pemetrexate
  • methicillin
  • plasminogen 
  • acai
  • american ginseng
  • cordyceps
  • tramadol/acetaminophen
  • belladonna alkaloids/phenobarbital
  • erythromycin topical/benzoyl peroxide
  • glucosamine sulfate
  • panax ginseng (suppl/herb)
  • tolnaftate
  • sulopenem etzadroxil/probenecid
  • sulfur hexafluoride
  • sotrovimab
  • arbaclofen
  • rifampin/isoniazid
  • clindamycin /tretinoin topical
  • benzoyl peroxide/clindamycin topical
  • apremilast
  • antivenins, centuroides (scorpion)
  • bamlanivimab and etesevimab
  • vilobelimab
  • gadobenate
  • pentosan polysulfate sodium
  • methylsalicylate/menthol/camphor topical
  • antivenin, black widow spider
  • benzoyl peroxide and hydrocortisone
  • clindamycin topical
  • isometheptene, dichloralphenazone and acetaminophen
  • acetaminophen and phenyltoloxamine
  • erythromycin topical
  • erythromycin ophthalmic
  • alpha hydroxy acids, topical
  • buprenorphine transdermal
  • butalbital/acetaminophen/caffeine
  • buprenorphine/samidorphan
  • buprenorphine subdermal implant
  • celecoxib/tramadol
  • drospirenone/ethinyl estradiol
  • resorcinol/sulfur
  • eflornithine
  • rifampin/isoniazid/pyrazinamide
  • tofersen
  • devil’s claw
  • ticarcillin/clavulanate
  • atropine/pralidoxime
  • aprepitant
  • suramin
  • phenelzine 
  • artichoke
  • american dogwood
  • attapulgite
  • atlantic cedar
  • axalimogene filolisbac
  • sodium thiosulfate & sodium nitrite
  • ataluren
  • omidubicel-onlv
  • capsicum
  • ginger
  • cryoprecipitate
  • bictegravir/emtricitabine/tenofovir DF
  • emtricitabine/tenofovir DF
  • fo-ti
  • siberian ginseng
  • granulocytes
  • zinc substituted heme C
  • zinc trihydroxide
  • ashwagandha 
  • cat’s claw
  • glandular products
  • SAMe
  • shark cartilage
  • altovis
  • feverfew
  • horse chestnut
  • magnesium aspartate
  • octacosanol
  • pleurisy root
  • star anise
  • butterbur
  • elderberry
  • licorice (Suppl/herb)
  • aconite
  • pentetate zinc trisodium
  • menthol topical/zinc oxide topical
  • corn-starch/kaolin/zinc oxide topical
  • 5-hydroxytryptophan (5-htp)
  • butcher’s broom
  • articulin
  • bearberry
  • goldenrod
  • progesterone, natural
  • black cohosh
  • wild yam
  • cranberry
  • dong quai
  • phytoestrogens
  • norethindrone
  • false Unicorn Root
  • raspberry Leaf
  • asafoetida
  • turmeric
  • dehydroepiandrosterone (DHEA)
  • hyaluronan
  • aliskiren/amlodipine
  • octreotide (Antidote)
  • tranexamic acid injection
  • duocal
  • neocate infant formula
  • pediatric Eo28
  • aloe
  • red clover
  • propolis
  • androstenedione
  • heartsease
  • comfrey
  • bilberry
  • chamomile
  • eyebright
  • calendula
  • sage
  • yucca
  • polypody
  • odevixibat
  • vinpocetine
  • olanzapine/samidorphan
  • creatine
  • yerba mate
  • spesolimab
  • azficel-T
  • tiludronate
  • estetrol and drospirenone
  • pseudoephedrine/fexofenadine
  • lincomycin
  • neomycin oral
  • fluocinolone acetonide, otic
  • tretinoin/ hydroquinone/ fluocinolone
  • halobetasol topical
  • hydrocortisone/​iodoquinol
  • penicillin G procaine /penicillin G benzathine
  • hydrocortisone probutate topical
  • colistin/neomycin/hydrocortisone/thonzonium otic
  • ebola zaire vaccine
  • hepatitis a/​b vaccine
  • vibegron
  • lindane
  • nystatin topical
  • respiratory syncytial virus (RSV) vaccine
  • chikungunya vaccine, live
  • tenecteplase
  • reteplase
  • anthrax vaccine adsorbed, adjuvanted
  • meningococcal ABCWY pentavalent vaccine
  • eculizumab
  • cholestyramine
  • tinzaparin
  • taurolidine/​citrate/​heparin
  • protein C concentrate
  • antithrombin alfa
  • antithrombin III
  • multivitamins, vision
  • ibuprofen/​chlorpheniramine/​pseudoephedrine
  • acetaminophen/ibuprofen
  • ibuprofen/pseudoephedrine
  • paclitaxel protein-bound
  • acetic acid vaginal
  • acetic acid otic
  • hydrocodone/ ibuprofen
  • methyl salicylate / isopropanol/ citronellyl acetate/ citric acid
  • ibuprofen and phenylephrine
  • acetylcysteine (Antidote)
  • iron/​folic acid/​vitamin/​mineral
  • iobenguane I-131
  • dolutegravir/rilpivirine
  • chlorhexidine topical
  • chlorhexidine oral
  • thyroid desiccated
  • proparacaine ophthalmic
  • podophyllum resin
  • phendimetrazine
  • phenoxybenzamine
  • polidocanol
  • phentermine and topiramate
  • piflufolastat F18
  • piperacillin/tazobactam
  • prednisolone and gentamicin ophthalmic
  • promethazine and codeine
  • poractant alfa
  • protamine sulfate
  • aflibercept intravitreal
  • prednicarbate
  • promethazine/dextromethorphan
  • codeine, phenylephrine, and promethazine
  • potassium phosphate
  • glatiramer acetate
  • gentamicin (Ophthalmic)
  • leniolisib
  • rezafungin
  • fluorometholone
  • dalfampridine
  • hydrocortisone topical 
  • empagliflozin and linagliptin
  • triamcinolone topical
  • minocycline topical
  • minocycline dental
  • ketotifen ophthalmic
  • darunavir and cobicistat
  • lidocaine topical
  • neomycin/polymyxin B/bacitracin/lidocaine (OTC)
  • lidocaine/ hydrocortisone
  • lidocaine anesthetic
  • lidocaine ophthalmic
  • lidocaine/tetracaine
  • desonide
  • dabigatran
  • fexofenadine
  • fluoride
  • decitabine and cedazuridine
  • dasiglucagon
  • hydroxypropyl cellulose ophthalmic
  • epoetin alfa
  • ibritumomab tiuxetan
  • trimethobenzamide
  • dexamethasone/ tobramycin
  • tafasitamab
  • valacyclovir
  • mebendazole
  • levoleucovorin
  • flaxseed
  • germanium
  • glutathione
  • lycopene
  • pygeum
  • horseradish
  • ziv-aflibercept
  • micafungin
  • trofinetide
  • taliglucerase alfa
  • tildrakizumab
  • sulopenem (Pending FDA Approval)
  • thyrotropin alfa
  • birch
  • thrombin, topical
  • tivozanib
  • tafluprost
  • methohexital
  • urea and hydrocortisone
  • unoprostone ophthalmic
  • trihexyphenidyl
  • ezetimibe
  • evolocumab
  • trifluridine and tipiracil
  • methenamine
  • misoprostol
  • miltefosine
  • rimantadine
  • maralixibat
  • coenzyme Q10
  • chlorella
  • garlic
  • forskolin
  • zavegepant
  • menotropins
  • margetuximab
  • meprobamate
  • melarsoprol
  • evening primrose oil
  • lemongrass
  • molindone
  • fenugreek
  • phytosterols
  • red yeast rice
  • uridine triacetate
  • tropicamide
  • incobotulinumtoxinA
  • Grape Seed Extract
  • carbachol ophthalmic
  • cosyntropin
  • cyclopentolate and phenylephrine
  • carteolol ophthalmic
  • pentazocine/naloxone
  • pentazocine/acetaminophen
  • casimersen
  • carisoprodol, aspirin, and codeine
  • carisoprodol
  • carboprost tromethamine
  • flurandrenolide
  • brinzolamide/brimonidine
  • betamethasone topical
  • omaveloxolone
  • bardoxolone
  • allogeneic processed thymus tissue
  • fluocinolone topical
  • tacrolimus topical
  • ruxolitinib topical
  • pimecrolimus topical
  • sofosbuvir, velpatasvir and voxilaprevir
  • sofosbuvir/velpatasvir
  • mitotane
  • elbasvir/​grazoprevir
  • wheat dextrin
  • vanadium
  • iron/folic acid/vitamin/mineral
  • molybdenum
  • sparsentan
  • velmanase alfa-tycv
  • pegcetacoplan
  • ferrous sulfate
  • cyclosporine ophthalmic
  • ferric pyrophosphate
  • ammonium lactate
  • etelcalcetide
  • iodoquinol
  • sucroferric oxyhydroxide
  • doxercalciferol
isoniazid + 

Severity : Monitor Closely
may enhance the serum concentration of CYP3A4 inhibitors

ethinyl estradiol

may decrease the levels of serum concentration of hormonal contraceptives

etonogestrel

may decrease the levels of serum concentration of hormonal contraceptives

ethinylestradiol

may decrease the levels of serum concentration of hormonal contraceptives

ethynodiol diacetate

may decrease the levels of serum concentration of hormonal contraceptives

bacillus clausii 

may decrease the therapeutic effect

mibefradil

may enhance the QTc-prolonging effect of QT-prolonging agents

ibandronate

may enhance the QTc-prolonging effect of QT-prolonging agents

trazodone

may enhance the QTc-prolonging effect of QT-prolonging agents

isradipine

may enhance the QTc-prolonging effect of QT-prolonging agents

treprostinil

may enhance the QTc-prolonging effect of QT-prolonging agents

epcoritamab

may increase the serum concentration of each other when combined

adagrasib

may increase the serum concentration of each other when combined

imiquimod topical

may increase the serum concentration of each other when combined

fluorouracil topical

may increase the serum concentration of each other when combined

peginterferon alfa-2b

may increase the serum concentration of each other when combined

medroxyprogesterone

may diminish the concentration of serum when combined with hormonal contraceptives

megestrol

may diminish the concentration of serum when combined with hormonal contraceptives

drospirenone

may diminish the concentration of serum when combined with hormonal contraceptives

dydrogesterone

may diminish the concentration of serum when combined with hormonal contraceptives

nabilone

may diminish the concentration of serum when combined with cannabinoid products

cannabidiol

may diminish the concentration of serum when combined with cannabinoid products

levonorgestrel

CYP3A4 Inducers: they may diminish the serum concentration of hormonal contraceptives

lynestrenol

CYP3A4 Inducers: they may diminish the serum concentration of hormonal contraceptives

medroxyprogesterone

CYP3A4 Inhibitors: they may diminish the serum concentration of hormonal contraceptives

megestrol

CYP3A4 Inhibitors: they may diminish the serum concentration of hormonal contraceptives

levonorgestrel

CYP3A4 Inhibitors: they may diminish the serum concentration of hormonal contraceptives

lynestrenol

CYP3A4 Inhibitors: they may diminish the serum concentration of hormonal contraceptives

abiraterone

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

lanreotide

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

cyproterone

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

triptorelin

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

darolutamide

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

desogestrel

may diminish the serum concentration when combined with hormonal contraceptives

mestranol

may diminish the serum concentration when combined with hormonal contraceptives

ulipristal

may diminish the serum concentration when combined with hormonal contraceptives

nilotinib

when both drugs are combined, there may be an increased effect of nilotinib by affecting hepatic or intestinal enzyme cyp3a4 metabolism  

clofazimine 

may increase the serum concentration of CYP3A4 substrates

deflazacort 

may enhance the serum concentrations of active metabolites

rifampin 

may diminish the serum concentration

acalabrutinib 

may diminish the serum concentration

budesonide and formoterol (inhalation) 

may enhance the serum concentration of CYP3A4 inhibitor

abiraterone 

may diminish the serum concentration of CYP3A4 inducers

clarithromycin 

may enhance serum concentrations of CYP3A4 inducers

dasatinib 

may diminish the serum concentration of CYP3A4 inducers

dexamethasone 

may diminish the serum concentration of CYP3A4 inducers

nifedipine 

may decrease the serum concentration when combined with CYP3A4 Inducers (Strong)

abemaciclib 

may increase the serum concentration of abemaciclib

adagrasib 

may increase the level of serum concentration of adagrasib

sparsentan 

may increase or decrease the activity of this enzyme when combined with sparsentan

alfentanil 

may diminish the serum concentration when combined with alfentanil

apixaban 

may diminish the serum concentration when combined with apixaban

aripiprazole 

may diminish the serum concentration when combined with aripiprazole

aripiprazole lauroxil 

may diminish serum concentrations when combined with aripiprazole lauroxil

atogepant 

may diminish the serum concentration when combined with atogepant

belumosudil 

may diminish the serum concentration when combined with belumosudil

brexpiprazole 

may diminish the serum concentration when combined with brexpiprazole

ubrogepant 

may diminish the serum concentration when combined with ubrogepant

fenfluramine 

may diminish the serum concentration when combined with fenfluramine

brivaracetam 

CYP2C19 Inducers: they may diminish the serum concentration of brivaracetam

cabozantinib 

cabozantinib :they may diminish the serum concentration of CYP3A4 Inducers

clopidogrel 

clopidogrel: they may enhance serum concentrations of CYP2C19 Inducers

cyclosporine 

cyclosporin: they may diminish the serum concentration of CYP3A4 Inducers

diltiazem 

diltiazem: they may diminish the serum concentration of CYP3A4 Inducers

enzalutamide 

enzalutamide: they may diminish serum concentrations of the active metabolites of CYP3A4 inducers

eravacycline 

CYP3A4 inducers: they may diminish the serum concentration of eravacycline

erlotinib 

erlotinib: they may diminish the serum concentration of CYP3A4 inducers

etoposide 

etoposide: they may diminish the serum concentration of CYP3A4 inducers

exemestane 

exemestane: they may diminish the serum concentration of CYP3A4 Inducers

felodipine 

felodipine: they may diminish the serum concentration of CYP3A4 Inducers

ganaxolone 

CYP3A4 inducers: they may diminish the serum concentration of ganaxolone

sotorasib 

may diminish the serum concentration of zanubrutnib

drospirenone/ethinyl estradiol/levomefolate 

may diminish the serum concentration of Hormonal Contraceptives

voxelotor 

may diminish the serum concentration of Voxelotor

brigatinib 

brigatinib: they may diminish the serum concentration of CYP3A4 Inducers

daclatasvir 

daclatasvir: they may diminish the serum concentration of CYP3A4 Inducers

guanfacine 

guanfacine: they may diminish the serum concentration of CYP3A4 Inducers

larotrectinib 

CYP3A4 Inducers: they may diminish the serum concentration of larotrectinib

lefamulin 

lefamulin: they may diminish the serum concentration of CYP3A4 Inducers

lorlatinib 

lorlatinib: they may increase the hepatotoxic effect of CYP3A4 Inducers

lurasidone 

lurasidone: they may diminish the serum concentration of CYP3A4 Inducers

maraviroc 

maraviroc: they may diminish the serum concentration of CYP3A4 Inducers

mitapivat 

mitapivat: they may diminish the serum concentration of CYP3A4 Inducers

perampanel 

perampanel: they may diminish the serum concentration of CYP3A4 Inducers

pirtobrutinib 

pirtobrutinib: they may diminish the serum concentration of CYP3A4 Inducers

praziquantel 

praziquantel: they may diminish the serum concentration of CYP3A4 Inducers

ripretinib 

ripretinib: they may diminish the serum concentration of CYP3A4 Inducers

zanubrutinib 

zanubrutinib: they may diminish the serum concentration of CYP3A4 Inducers

methylprednisolone 

may diminish the concentration of serum when combined with methylprednisolone

etonogestrel 

may diminish the serum concentration of Hormonal Contraceptives

etonogestrel/ethinyl estradiol 

may diminish the serum concentration of Hormonal Contraceptives

medroxyprogesterone

may diminish the concentration of serum when combined with hormonal contraceptives

megestrol

may diminish the concentration of serum when combined with hormonal contraceptives

drospirenone

may diminish the concentration of serum when combined with hormonal contraceptives

dydrogesterone

may diminish the concentration of serum when combined with hormonal contraceptives

indinavir 

may diminish the concentration of serum when combined with indinavir

avanafil 

avanafil: they may enhance the serum concentration of CYP3A Inhibitors

daridorexant 

daridorexant: they may enhance the serum concentration of CYP3A Inhibitors

encorafenib 

encorafenib: they may enhance the serum concentration of CYP3A Inhibitors

eplerenone 

eplerenone: they may enhance the serum concentration of CYP3A Inhibitors

fexinidazole 

fexinidazole: they may diminish serum concentrations of CYP3A Inhibitors

ivacaftor 

ivacaftor: they may enhance the serum concentration of CYP3A Inhibitors

midazolam 

midazolam: they may enhance the serum concentration of CYP3A Inhibitors

ranolazine 

ranolazine: they may enhance the serum concentration of CYP3A4 Inducers

sirolimus 

sirolimus: they may enhance the serum concentration of CYP3A4 Inducers

triazolam 

triazolam: they may enhance the serum concentration of CYP3A4 Inducers

ubrogepant 

ubrogepant: they may enhance the serum concentration of CYP3A Inhibitors

desogestrel

may diminish the serum concentration when combined with hormonal contraceptives

mestranol

may diminish the serum concentration when combined with hormonal contraceptives

ulipristal

may diminish the serum concentration when combined with hormonal contraceptives

epcoritamab

may diminish the serum concentration of each other when combined

adagrasib

may diminish the serum concentration of each other when combined

imiquimod topical

may diminish the serum concentration of each other when combined

fluorouracil topical

may diminish the serum concentration of each other when combined

peginterferon alfa-2b

may diminish the serum concentration of each other when combined

abiraterone

may diminish the serum concentration of each other when combined

cyproterone

may diminish the serum concentration of each other when combined

darolutamide

may diminish the serum concentration of each other when combined

dienogest/estradiol valerate

may diminish the serum concentration of each other when combined

flutamide

may diminish the serum concentration of each other when combined

abacavir and lamivudine

may enhance the serum concentration of CYP3A4 inhibitors

lenacapavir

may enhance the serum concentration of CYP3A4 inhibitors

nirmatrelvir/ritonavir

may enhance the serum concentration of CYP3A4 inhibitors

peginterferon alfa-2b

may enhance the serum concentration of CYP3A4 inhibitors

abiraterone

may enhance the serum concentration of CYP3A4 inhibitors

simvastatin 

simvastatin: it may diminish the serum concentration of CYP3A4 Inducers

ribavirin

may diminish the concentration of serum when combined with antihepaciviral products

lorlatinib

the effect of isoniazid is increased by lorlatinib, by altering intestinal or hepatic CYP3A4 enzyme metabolism

ruxolitinib

it increases the effect or level of ruxolitinib by altering the intestinal or hepatic CYP3A4 enzyme metabolism

fexinidazole 

it increases the concentration of CYP3A4 substrates in the serum

fusidic acid 

it increases the concentration of CYP3A4 substrates in serum

doravirine 

they decrease the concentration of doravirine in the serum

nirmatelvir/ritonavir 

may diminish the serum concentration

nisoldipine 

may diminish the serum concentration

rilpivirine 

they decrease the concentration of rilpivirine

macimorelin 

may decrease the serum concentration of macimorelin

avapritinib 

may enhance the serum concentration

lenacapavir 

may decrease the serum concentration of lenacapavir

buprenorphine 

they decrease the concentration of buprenorphine in the serum

abemaciclib 

may reduce the level of serum concentration of abemaciclib

adagrasib 

may diminish the serum concentration of CYP3A4 inducers

alpelisib 

may diminish the serum concentration of CYP3A4 inducers

apremilast 

may diminish the serum concentration of CYP3A4 inducers

asunaprevir 

may diminish the serum concentration of CYP3A4 inducers

avanafil 

may diminish the serum concentration of CYP3A4 inducers

bedaquiline 

may diminish serum concentrations of CYP3A4 inducers

bortezomib 

may diminish the serum concentration of CYP3A4 inducers

deflazacort 

may diminish serum concentrations of CYP3A4 inducers

glasdegib 

they decrease the concentration of glasdegib in the serum

infigratinib 

they decrease the concentration of active metabolites of infigratinib in the serum

infigratinib 

they decrease the concentration of active metabolites of infigratinib in the serum

pimozide 

CYP3A4 inhibitors increase the concentration of pimozide in the serum

elbasvir/​grazoprevir 

may enhance the serum concentration of elbasvir/grazoprevir

buspirone 

it increases the concentration of CYP3A4 substrates in the serum

tafamidis 

may enhance the serum concentration of tafamidis

tolvaptan 

may diminish the serum concentration when combined with tolvaptan

abrocitinib 

abrocitinib: they may diminish the serum concentration of CYP2C19 Inducers

capmatinib 

CYP3A4 Inducers: they may diminish the serum concentration of capmatinib

ceritinib 

ceritinib: they may diminish the serum concentration of CYP3A4 Inducers

crizotinib 

crizotinib: they may diminish the serum concentration of CYP3A4 Inducers

duvelisib 

duvelisib: they may diminish the serum concentration of CYP3A4 Inducers

avacopan 

The serum concentration of Avacopan may be decreased by strong CYP3A4 inducers

lurbinectedin 

they decrease the concentration of lurbinectedin in the serum

lemborexant 

may diminish the concentration of serum when combined with lemborexant

pacritinib 

may enhance the concentration of serum when combined with CYP3A4 substrates

treosulfan 

may enhance the concentration of serum when combined with CYP3A4 substrates

naxitamab 

naxitinib: they may diminish the serum concentration of CYP3A4 Inducers

bosutinib 

bosutinib: they may diminish the serum concentration of CYP3A4 Inducers

cariprazine 

cariprazine: they may diminish the serum concentration of CYP3A4 Inducers

cobimetinib 

cobimetinib: they may diminish the serum concentration of CYP3A4 Inducers

daridorexant 

daridorexant: they may diminish the serum concentration of CYP3A4 Inducers

elacestrant 

CYP3A4 Inducers: they may diminish the serum concentration of elacestrant

fedratinib 

fedratinib: they may diminish the serum concentration of CYP3A4 Inducers

finerenone (Rx) 

finerenone: they may diminish the serum concentration of CYP3A4 Inducers

flibanserin 

flibanserin: they may diminish the serum concentration of CYP3A4 Inducers

ibrexafungerp 

ibrexafungerp: they may diminish the serum concentration of CYP3A4 Inducers

ivabradine 

ivabradine: they may diminish the serum concentration of CYP3A4 Inducers

leniolisib 

leniolisib: they may diminish the serum concentration of CYP3A4 Inducers

mavacamten 

mavacamten: they may diminish the serum concentration of CYP3A4 Inducers

neratinib 

neratinib: they may diminish the serum concentration of CYP3A4 Inducers

olaparib 

olaparib: they may diminish the serum concentration of CYP3A4 Inducers

olutasidenib 

olutasidenib: they may diminish the serum concentration of CYP3A4 Inducers

omaveloxolone 

omaveloxolone: they may diminish the serum concentration of CYP3A4 Inducers

pemigatinib 

pemigatinib: they may diminish the serum concentration of CYP3A4 Inducers

rimegepant 

rimegepant: they may diminish the serum concentration of CYP3A4 Inducers

selumetinib 

selumetinib: they may diminish the serum concentration of CYP3A4 Inducers

sertraline 

sertraline: they may diminish the serum concentration of CYP3A4 Inducers

tazemetostat 

tazemetostat: they may diminish the serum concentration of CYP3A4 Inducers

ulipristal 

ulipristal: they may diminish the serum concentration of CYP3A4 Inducers

venetoclax 

venetoclax: they may diminish the serum concentration of CYP3A4 Inducers

voclosporin 

voclosporin: they may diminish the serum concentration of CYP3A4 Inducers

vonoprazan fumarate 

vonoprazan fumarate: they may enhance the serum concentration of CYP3A4 Inducers

vorapaxar 

vorapaxar: they may diminish the serum concentration of CYP3A4 Inducers

isavuconazonium sulfate 

may diminish the concentration of serum when combined with isavuconazonium sulfate

macitentan and tadalafil 

may diminish the serum concentration when combined

ribavirin

may diminish the concentration of serum when combined with antihepaciviral products

axitinib 

may diminish the concentration of serum when combined with axitinib

dasabuvir 

may diminish the concentration of serum when combined with dasabuvir

entrectinib 

may diminish the concentration of serum when combined with entrectinib

tamoxifen 

they decrease the concentration of active metabolites of tamoxifen in serum

aprepitant 

aprepitant: they may enhance the serum concentration of CYP3A Inhibitors

domperidone 

domperidone: they may enhance the serum concentration of CYP3A Inhibitors

ivabradine 

ivabradine: they may enhance the serum concentration of CYP3A Inhibitors

lomitapide 

lomitapide: they may enhance the serum concentration of CYP3A Inhibitors

pacritinib 

pacritinib: they may enhance the serum concentration of CYP3A Inhibitors

sertindole 

sertindole: they may enhance the serum concentration of CYP3A Inhibitors

talazoparib

may diminish the serum concentration of each other when combined

niraparib

may diminish the serum concentration of each other when combined

tiludronic acid

antacids reduce the systemic absorption of isoniazid

almasilate

antacids reduce the systemic absorption of isoniazid

aluminum hydroxide

antacids reduce the systemic absorption of isoniazid

calcium carbonate

antacids reduce the systemic absorption of isoniazid

magaldrate

antacids reduce the systemic absorption of isoniazid

estropipate

may reduce the level of serum concentration of estrogen drugs

bazedoxifene/conjugated estrogens

may reduce the level of serum concentration of estrogen drugs

conjugated estrogens

may reduce the level of serum concentration of estrogen drugs

diethylstilbestrol

may reduce the level of serum concentration of estrogen drugs

esterified estrogens

may reduce the level of serum concentration of estrogen drugs

estropipate

may increase the levels of serum concentration of estrogen derivatives

anastrozole

may increase the levels of serum concentration of estrogen derivatives

bazedoxifene/conjugated estrogens

may increase the levels of serum concentration of estrogen derivatives

esterified estrogens

may increase the levels of serum concentration of estrogen derivatives

estetrol

may increase the levels of serum concentration of estrogen derivatives

ethinyl estradiol

may increase the levels of serum concentration of hormonal contraceptives

etonogestrel

may increase the levels of serum concentration of hormonal contraceptives

ethinylestradiol

may increase the levels of serum concentration of hormonal contraceptives

ethynodiol diacetate

may increase the levels of serum concentration of hormonal contraceptives

acetaminophen 

may have an increased hepatotoxic effect when combined with acetaminophen

synthetic conjugated estrogens, a

may increase the serum concentration

synthetic conjugated estrogens, b

may increase the serum concentration

valrubicin

may increase the levels of serum concentration

doxorubicin

may increase the levels of serum concentration

epirubicin

may increase the levels of serum concentration

mitoxantrone

may increase the levels of serum concentration

mitomycin

may increase the levels of serum concentration

ziv-aflibercept

may increase the levels of serum concentration

tivozanib

may increase the levels of serum concentration

abemaciclib

may increase the levels of serum concentration

acalabrutinib

may increase the levels of serum concentration

bosutinib

may increase the levels of serum concentration

sacituzumab govitecan

may decrease the levels of serum concentrations

topotecan

may decrease the levels of serum concentrations

epirubicin

may decrease the levels of serum concentrations

etoposide

may decrease the levels of serum concentrations

irinotecan

may decrease the levels of serum concentrations

sacituzumab govitecan

may decrease the levels of serum concentrations

topotecan

may decrease the levels of serum concentrations

etoposide

may decrease the levels of serum concentrations

irinotecan

may decrease the levels of serum concentrations

teniposide

may decrease the levels of serum concentrations

ziv-aflibercept

may decrease the levels of serum concentration

dacomitinib

may decrease the levels of serum concentration

pacritinib

may decrease the levels of serum concentration

asciminib

may decrease the levels of serum concentration

pemigatinib

may decrease the levels of serum concentration

dihydroergotamine intranasal 

dihydroergotamine intranasal and isoniazid are both known to elevate serotonin levels

remifentanil

may reduce the levels of serum concentration

hydrocodone/pseudoephedrine

may reduce the levels of serum concentration

codeine

may reduce the levels of serum concentration

morphine

may reduce the levels of serum concentration

valrubicin

may decrease the levels of serum concentration

doxorubicin

may decrease the levels of serum concentration

epirubicin

may decrease the levels of serum concentration

mitoxantrone

may decrease the levels of serum concentration

mitomycin

may decrease the levels of serum concentration

epcoritamab

may decrease the levels of serum concentration

ziv-aflibercept

may decrease the levels of serum concentration

tivozanib

may decrease the levels of serum concentration

acalabrutinib

may decrease the levels of serum concentration

bosutinib

may decrease the levels of serum concentration

abemaciclib

may decrease the levels of serum concentration

paclitaxel/encequidar

may decrease the levels of serum concentration

paclitaxel

may decrease the levels of serum concentration

cabazitaxel

may decrease the levels of serum concentration

docetaxel

may decrease the levels of serum concentration

vinblastine

may decrease the levels of serum concentration

vincristine

may decrease the levels of serum concentration

vindesine

may decrease the levels of serum concentration

vinflunine

may decrease the levels of serum concentration

vinorelbine

may decrease the levels of serum concentration

almasilate

isoniazid: they may diminish the absorption of antacids

aluminum hydroxide

isoniazid: they may diminish the absorption of antacids

calcium carbonate

isoniazid: they may diminish the absorption of antacids

magaldrate

isoniazid: they may diminish the absorption of antacids

magnesium trisilicate

isoniazid: they may diminish the absorption of antacids

tolazoline

may decrease the serum concentration

captopril/hydrochlorothiazide

may decrease the serum concentration

mibefradil

may decrease the serum concentration

indoramin

may decrease the serum concentration

minoxidil topical

may decrease the serum concentration

desmopressin acetate

may decrease the serum concentration

conivaptan

may decrease the serum concentration

tolvaptan

may decrease the serum concentration

desmopressin acetate

may increase the serum concentration

conivaptan

may increase the serum concentration

tolvaptan

may increase the serum concentration

amlodipine/atorvastatin

may decrease the serum concentration

atorvastatin

may decrease the serum concentration

cerivastatin

may decrease the serum concentration

fluvastatin

may decrease the serum concentration

lovastatin

may decrease the serum concentration

bromazepam 

when bromazepam and isoniazid are used together, there is a potential reduction in the bromazepam's metabolism

alprazolam 

When alprazolam and isoniazid is used together, this leads to reduction in the alprazolam’s metabolism

dexrabeprazole 

When dexrabeprazole and isoniazid is used together, this leads to reduction in the dexrabeprazole’s metabolism

carbimazole

It may enhance the risk of adverse effects when combined with Mycolic acid inhibitors

potassium perchlorate

It may enhance the risk of adverse effects when combined with Mycolic acid inhibitors

tiludronic acid

isoniazid: they may diminish the absorption of antacids

hydrocodone and homatropine

it may decrease the levels of serum concentration

dezocine

it may decrease the levels of serum concentration

oxycodone

it may decrease the levels of serum concentration

naloxegol

it may decrease the levels of serum concentration

oxaprozin

it may decrease the levels of serum concentration

etoposide

when both drugs are combined, there may be a reduced metabolism of etoposide   

vincristine

when both drugs are combined, there may be a decreased metabolism of vincristine  

brentuximab

has a synergistic effect over brentuximab vedotin, by showing altered intestinal/hepatic CYP3A4 enzyme metabolism.

abemaciclib

when both drugs are combined, there may be an increased effect of abemaciclib by affecting hepatic or intestinal enzyme cyp3a4 metabolism  

finasteride

it increases the effect or level of finasteride by altering the intestinal/hepatic enzyme CYP3A4 metabolism

lacosamide

may increase the level by affecting hepatic enzyme CYP3A4 metabolism

clorazepate

may increase the level by affecting hepatic enzyme CYP3A4 metabolism

alprazolam 

may enhance the serum concentration

triazolam 

may enhance the serum concentration of CYP3A4 inhibitors

ziconotide 

may increase the level by affecting hepatic enzyme CYP3A4 metabolism

clozapine 

may decrease the levels of serum concentration of clozapine

hydrocodone/​chlorpheniramine/​pseudoephedrine 

may diminish the serum concentration

osilodrostat 

may decrease the serum concentration

osilodrostat 

may increase the serum concentration

ospemifene 

may increase the serum concentration of CYP3A4 substrates

erdafitinib 

may decrease the serum concentration of erdafitinib.

azelastine/fluticasone intranasal 

may enhance the serum concentration

macitentan 

may decrease the serum concentration of macitentan

macitentan 

may enhance the serum concentration of macitentan

pretomanid 

may decrease the level of serum concentration of pretomanid

eliglustat 

CYP3A4 Inducers may decrease the serum concentration of eliglustat

encorafenib 

may decrease the serum concentration of encorafenib

estropipate

may decrease the serum concentration of estrogen derivatives

bazedoxifene/conjugated estrogens

may decrease the serum concentration of estrogen derivatives

diethylstilbestrol

may decrease the serum concentration of estrogen derivatives

esterified estrogens

may decrease the serum concentration of estrogen derivatives

estetrol

may decrease the serum concentration of estrogen derivatives

prednisolone 

may diminish the serum concentration of corticosteroids

may enhance the serum concentration of CYP3A4 inhibitors

acetaminophen/pamabrom 

may increase the hepatotoxic effect of acetaminophen

calcitriol 

may increase the serum concentration

amlodipine 

may diminish the serum concentration of CYP3A4 inducers

atorvastatin 

may diminish the serum concentration of CYP3A4 inducers

benperidol 

may diminish the serum concentration of CYP3A4 inducers

bisoprolol 

may diminish the serum concentration of CYP3A4 inducers

cabazitaxel 

may diminish the serum concentration of CYP3A4 inducers

calcifediol 

may diminish the serum concentration of CYP3A4 inducers

carbamazepine 

may diminish the serum concentration of CYP3A4 inducers

chlorpropamide 

may diminish the serum concentration of CYP3A4 inducers

clonazepam 

may diminish the serum concentration of CYP3A4 inducers

escitalopram 

may diminish the serum concentration of CYP3A4 inducers

doxercalciferol 

may enhance serum concentrations when combined with doxercalciferol

itraconazole 

may increase the level of serum concentration of itraconazole

itraconazole 

may decrease the level of serum concentrations of itraconazole

selpercatinib 

may diminish the serum concentration when combined with selpercatinib

nimodipine 

may diminish the serum concentration when combined with nimodipine

upadacitinib 

may diminish the serum concentration when combined with upadacitinib

tivozanib 

may reduce the levels of serum concentration of tivozanib

lidocaine anesthetic 

may diminish the serum concentration of lidocaine

nintedanib 

may diminish the serum concentration when combined with nintedanib

ziprasidone 

may diminish the serum concentration when combined with ziprasidone

lovastatin 

may enhance the serum concentration when combined

eszopiclone 

eszopiclone: they may diminish the serum concentration of CYP3A4 Inducers

ethosuximide 

ethosuximide: they may diminish the serum concentration of CYP3A4 Inducers

hydrocodone 

hydrocodone: they may diminish the serum concentration of CYP3A4 Inducers

mefloquine 

mefloquine: they may diminish the serum concentration of CYP3A4 Inducers

meperidine 

meperidine: they may diminish the serum concentration of CYP3A4 Inducers

methadone 

methadone: they may diminish the serum concentration of CYP3A4 Inducers

alprazolam 

Strong CYP3A4 inducers may lower the serum concentration of alprazolam

amiodarone 

Strong CYP3A4 inducers may decrease serum concentrations of the active metabolite(s) of amiodarone

roflumilast 

may increase the levels of serum concentration

ribociclib 

may increase the levels of serum concentration

triptorelin

may increase the levels of serum concentration

elagolix

may increase the levels of serum concentration

urofollitropin

may increase the levels of serum concentration

gonadoreline hydrochloride

may increase the levels of serum concentration

ganirelix acetate

may increase the levels of serum concentration

triptorelin

may decrease the levels of serum concentration

elagolix

may decrease the levels of serum concentration

urofollitropin

may decrease the levels of serum concentration

gonadoreline hydrochloride

may decrease the levels of serum concentration

ganirelix acetate

may decrease the levels of serum concentration

ergonovine

may decrease the levels of serum concentration

dihydroergocristine

may decrease the levels of serum concentration

dihydroergotamine

may decrease the levels of serum concentration

ergoloid mesylate

may decrease the levels of serum concentration

ergometrine

may decrease the levels of serum concentration

buprenorphine buccal 

may enhance the serum concentration of Buprenorphine

estrogens esterified/methyltestosterone             

may diminish the serum concentration when combined

acetaminophen 

may increase the hepatotoxic effect when combined

fluticasone (topical) 

may enhance the concentration of serum when combined with fluticasone

aprepitant 

aprepitant: they may diminish the serum concentration of CYP3A4 Inducers

codeine 

codeine: they may diminish serum concentrations of CYP3A4 Inducers

copanlisib 

copanlisib: they may diminish the serum concentration of CYP3A4 Inducers

omeprazole 

omeprazole: they may diminish the serum concentration of CYP2C19 Inducers

diazepam 

diazepam: they may diminish the serum concentration of CYP3A4 Inducers

disopyramide 

disopyramide: they may diminish the serum concentration of CYP3A4 Inducers

elvitegravir 

elvitegravir: they may diminish the serum concentration of CYP3A4 Inducers

everolimus 

everolimus: they may diminish the serum concentration of CYP3A4 Inducers

fentanyl 

fentanyl: they may diminish the serum concentration of CYP3A4 Inducers

ibrutinib 

ibrutinib: they may diminish the serum concentration of CYP3A4 Inducers

idelalisib 

idelalisib: they may diminish the serum concentration of CYP3A4 Inducers

ifosfamide 

ifosfamide: they may diminish serum concentrations of CYP3A4 Inducers

imatinib 

imatinib: they may diminish the serum concentration of CYP3A4 Inducers

isradipine 

isradipine: they may diminish the serum concentration of CYP3A4 Inducers

istradefylline 

istradefylline: they may diminish the serum concentration of CYP3A4 inducers

lapatinib 

lapatinib: they may diminish the serum concentration of CYP3A4 Inducers

lercanidipine 

lercanidipine: they may diminish the serum concentration of CYP3A4 Inducers

levamlodipine 

levamlodipine: they may diminish the serum concentration of CYP3A4 Inducers

mianserin 

mianserin: they may diminish the serum concentration of CYP3A4 Inducers

midazolam 

midazolam: they may diminish the serum concentration of CYP3A4 Inducers

taurursodiol 

may diminish the concentration of serum when combined with taurursodiol

midostaurin 

midostaurin: they may diminish the serum concentration of CYP3A4 Inducers

naldemedine 

naldemedine: they may diminish the serum concentration of CYP3A4 Inducers

naloxegol 

naloxegol: they may diminish the serum concentration of CYP3A4 Inducers

nilvadipine 

nilvadipine: they may diminish the serum concentration of CYP3A4 Inducers

osimertinib 

osimertinib: they may diminish the serum concentration of CYP3A4 Inducers

oxycodone 

oxycodone: they may diminish the serum concentration of CYP3A4 Inducers

prednisone (Rx) 

prednisone: they may diminish the serum concentration of CYP3A4 Inducers

quetiapine 

quetiapine: they may diminish the serum concentration of CYP3A4 Inducers

quinidine 

quinidine: they may diminish the serum concentration of CYP3A4 Inducers

quinine 

quinine: they may diminish the serum concentration of CYP3A4 Inducers

regorafenib 

regorafenib: they may diminish the serum concentration of CYP3A4 Inducers

repaglinide 

repaglinide: they may diminish the serum concentration of CYP3A4 Inducers

ribociclib 

ribociclib: they may diminish the serum concentration of CYP3A4 Inducers

samidorphan 

samidorphan: they may diminish the serum concentration of CYP3A4 Inducers

sildenafil 

sildenafil: they may diminish the serum concentration of CYP3A4 Inducers

sorafenib 

sorafenib: they may diminish the serum concentration of CYP3A4 Inducers

thiotepa 

thiotepa: they may enhance serum concentrations of CYP3A4 Inducers

ticagrelor 

ticagrelor: they may diminish serum concentrations of CYP3A4 Inducers

tofacitinib 

tofacitinib: they may diminish the serum concentration of CYP3A4 Inducers

toremifene 

toremifene: they may diminish serum concentrations of CYP3A4 Inducers

trabectedin 

trabectedin: they may diminish the serum concentration of CYP3A4 Inducers

tramadol 

tramadol: they may diminish the serum concentration of CYP3A4 Inducers

trazodone 

trazodone: they may diminish the serum concentration of CYP3A4 Inducers

tucatinib 

tucatinib: they may diminish the serum concentration of CYP3A4 Inducers

vemurafenib 

vemurafenib: they may diminish the serum concentration of CYP3A4 Inducers

verapamil 

verapamil: they may diminish the serum concentration of CYP3A4 Inducers

vilazodone 

vilazodone: they may diminish the serum concentration of CYP3A4 Inducers

zolpidem 

zolpidem: they may diminish the serum concentration of CYP3A4 Inducers

zopiclone 

zopiclone: they may diminish the serum concentration of CYP3A4 Inducers

methylergometrine 

may decrease the concentration of serum when combined with methylergometrine

cyclosporine 

cyclosporine: they may enhance the serum concentration of CYP3A4 Inhibitors

ixabepilone 

ixabepilone: they may enhance the serum concentration of CYP3A Inhibitors

nimodipine 

nimodipine: they may enhance the serum concentration of CYP3A Inhibitors

tacrolimus 

tacrolimus: they may enhance the serum concentration of CYP3A Inhibitors

leuprolide and norethindrone 

may diminish the serum concentration of each other when combined

artemether/lumefantrine 

may diminish the concentration of serum when combined with artemether and lumefantrine

atazanavir 

may diminish the concentration of serum when combined with atazanavir

benzhydrocodone/acetaminophen 

may diminish the concentration of serum when combined with benzhydrocodone

tolazoline

may increase the serum concentration

captopril/hydrochlorothiazide

may increase the serum concentration

mibefradil

may increase the serum concentration

indoramin

may increase the serum concentration

minoxidil topical

may increase the serum concentration

ivosidenib 

it decreases the concentration of CYP3A4 inducers in serum

mometasone/intranasal 

mometasone (Nasal): they may enhance the serum concentration of CYP3A Inhibitors

amlodipine 

amlodipine: they may enhance the serum concentration of CYP3A Inhibitors

clozapine 

clozapine: they may enhance the serum concentration of CYP3A Inhibitors

darifenacin 

darifenacin: they may enhance the serum concentration of CYP3A Inhibitors

eszopiclone 

eszopiclone: they may enhance the serum concentration of CYP3A inhibitors

fedratinib 

fedratinib: they may enhance the serum concentration of CYP3A inhibitors

lapatinib 

lapatinib: they may enhance the serum concentration of CYP3A inhibitors

pinaverium

It may enhance the risk of adverse effects when combined with CYP3A4 inducers

rolapitant 

rolapitant: they may diminish the serum concentration of CYP3A4 Inducers

nicardipine 

nicardipine: they may diminish the serum concentration of CYP3A4 Inducers

dapoxetine 

dapoxetine: they may diminish the serum concentration of CYP3A4 Inducers

brimonidine 

brimonidine: they may diminish the serum concentration of CYP3A4 Inducers

cimetidine 

cimetidine: they may diminish the serum concentration of CYP3A4 Inducers

diazoxide 

diazoxide: they may diminish the serum concentration of CYP3A4 Inducers

flunarizine 

flunarizine: they may diminish the serum concentration of CYP3A4 Inducers

melatonin 

melatonin: they may diminish the serum concentration of CYP3A4 Inducers

methylphenidate 

methylphenidate: they may diminish the serum concentration of CYP3A4 Inducers

molsidomine 

molsidomine: they may diminish the serum concentration of CYP3A4 Inducers

atosiban 

atosiban: they may diminish the serum concentration of CYP3A4 Inducers

alfuzosin 

alfuzosin: they may diminish the serum concentration of CYP3A4 Inducers

dimercaprol 

dimercaprol: they may diminish the serum concentration of CYP3A4 Inducers

medical cannabis 

cannabis: they may enhance the serum concentration of CYP3A4 inducers

propofol 

propofol: they may enhance the serum concentration of CYP3A4 inducers

tacrolimus 

tacrolimus: they may enhance the serum concentration of CYP3A4 Substrates

warfarin 

warfarin: they may enhance the serum concentration of CYP3A4 inducers

protriptyline

tricyclic antidepressants: they may enhance the serum concentration of CYP3A4 inducers

nabilone

cannabinoid receptor agonists: they may enhance the serum concentration of CYP3A4 inducers

cannabidiol

cannabinoid receptor agonists: they may enhance the serum concentration of CYP3A4 inducers

dydrogesterone 

an increase in rate of metabolism may be seen

metronidazole/tetracycline/bismuth subsalicylate 

by altering CYP2E1 metabolism, the levels of isoniazid may be increased with metronidazole

hesperetin 

When isoniazid is aided by hesperetin, it reduces hesperetin’s metabolism

tenofovir disoproxil fumarate or tenofovir DF 

may decrease the level of serum concentration

tenofovir alafenamide 

may decrease the level of serum concentration

tenofovir disoproxil 

may decrease the level of serum concentration

sugammadex 

it may reduce the therapeutic effect

ixazomib

isoniazid, when taken with ixazomib, alters the intestinal/hepatic CYP3A4 enzyme metabolism

remifentanil

CYP3A4 inducers decrease the concentration of opioids

hydrocodone/pseudoephedrine

CYP3A4 inducers decrease the concentration of opioids

codeine

CYP3A4 inducers decrease the concentration of opioids

morphine

CYP3A4 inducers decrease the concentration of opioids

ethinyl estradiol

CYP3A4 inducers decrease the concentration of hormonal contraceptives in the serum

etonogestrel

CYP3A4 inducers decrease the concentration of hormonal contraceptives in the serum

ethinylestradiol

CYP3A4 inducers decrease the concentration of hormonal contraceptives in the serum

ethynodiol diacetate

CYP3A4 inducers decrease the concentration of hormonal contraceptives in the serum

 

Dosage Forms & Strengths 

Tablets 

50mg 

100mg 

300mg 

Tuberculosis (TB) 

Latent tuberculosis infection
:


>30kg:300mg orally every day for nine months

3-month regimen
900mg orally weekly once for three months

Active tuberculosis disease
5mg/kg orally/intramuscularly every day.Do not exceed 300mg every day



 

Dosage Forms & Strengths 

Tablets 

50mg 

100mg 

300mg 

Tuberculosis (TB) 

Latent tuberculosis infection
:


10-15mg/kg orally every day

3-month regimen
<2 years: Not recommended
>12 years: 900mg orally weekly once for three months

Active tuberculosis disease
10-15mg/kg orally every day. Do not exceed 300mg every day



 

Refer adult dosing 

Frequency defined:

>10%

Peripheral neuropathy

Nausea

Stomach pain

Loss of appetite

Vomiting

Weakness

1-10%

Dizziness

Hyperreflexia

<1%

Anemia

Thrombocytopenia

Agranulocytosis

Megaloblastic anemia

Systemic lupus erythematous

Black Box Warning:

Fatal hepatitis

Contraindication:

Hypersensitivity

Cautions:

Renal/Hepatic impairment

Pregnancy consideration: C 

Lactation: The drug is excreted in the human breast milk and is safe for nursing women  

Pregnancy category: 

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.   

<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. 

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.    

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.    

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.    

Category N: There is no data available for the drug under this category 

Pharmacodynamics:

It is effective against mycobacterium species.

It is a highly specialized agent that does not work against other microbes.

When mycobacteria grow quickly, isoniazid is bactericidal; when they grow slowly, it is bacteriostatic.

Pharmacokinetics:

Absorption

Rapid absorption

Peak plasma time is achieved in 1 to2 hours

Distribution

It is distributed widely throughout CSF’s tissues and fluids.

It is also known to cross the placenta and be excreted in breast milk.

10 to 15% of the drug is bound to plasma proteins.

Metabolism

Isoniazid undergoes hepatic metabolism.

Elimination and excretion

50 to 70% of the drug is eliminated through urine.

Half-life

Slow acetylators- 2 hours to 5 hours

Fast acetylators- 0.5 hours to 1.6 hours

Administration:

Isoniazid can be administered orally/IV as advised by the physician.

Patient information leaflet

Generic Name: isoniazid

Pronounced: [eye-so-NYE-a-zid]

Why do we use isoniazid?

Isoniazid is an antibiotic used to treat and prevent tuberculosis (TB).

It belongs to a class of antibiotics called antituberculosis agents.

Isoniazid is used to treat TB infections in the lungs and other parts of the body.

It is typically used in combination with other TB medications to ensure that the infection is fully treated and to prevent the development of drug-resistant TB

Isoniazid is an antibiotic used to treat and prevent tuberculosis (TB).

It belongs to a class of antibiotics called antituberculosis agents.

Isoniazid is used to treat TB infections in the lungs and other parts of the body.

It is typically used in combination with other TB medications to ensure that the infection is fully treated and to prevent the development of drug-resistant TB

isoniazid

Brand Name :

Nydrazid

Synonyms :

Isoniazid

Class :

Hydrazide derivatives




No data available for drug.

Dosage Forms & Strengths 

Tablets 

50mg 

100mg 

300mg 

Tuberculosis (TB) 

Latent tuberculosis infection
:


>30kg:300mg orally every day for nine months

3-month regimen
900mg orally weekly once for three months

Active tuberculosis disease
5mg/kg orally/intramuscularly every day.Do not exceed 300mg every day



Dosage Forms & Strengths 

Tablets 

50mg 

100mg 

300mg 

Tuberculosis (TB) 

Latent tuberculosis infection
:


10-15mg/kg orally every day

3-month regimen
<2 years: Not recommended
>12 years: 900mg orally weekly once for three months

Active tuberculosis disease
10-15mg/kg orally every day. Do not exceed 300mg every day



Refer adult dosing 

DRUG INTERACTION

isoniazid

&

  • patisiran
  • imetelstat
  • phenylephrine ophthalmic
  • myoinositol
  • vasicinone
  • soda lime
  • fisetin
  • Reynoutria Japonica
  • Coco Monoethanolamide
  • Betadex
  • lithopone
  • cyperus rotundus
  • papaya juice
  • 1-naphthaleneacetic acid
  • Nordazepam
  • Glechoma hederacea
  • Alternanthera sessilis
  • nicofetamide
  • napthol asol
  • cocamidopropyl betaine
  • musa x paradisiaca
  • dicyclomine/mefenamic acid
  • Sorghum
  • Manganese citrate
  • tovorafenib
  • mefenamic acid/paracetamol
  • eschscholzia californica
  • canna indica root
  • tranexamic acid/mefenamic acid
  • dexverapamil
  • sitogluside
  • secalciferol
  • cefatrizine
  • Sedum Acre
  • Flurogestone
  • Fluocortin
  • Bifendate
  • piprozolin
  • aminacrine undecylate
  • ethylenediamine mandelate
  • pelubiprofen
  • hesperetin
  • butethamine
  • epitiostanol
  • androstenediol
  • Nitroxoline
  • Iocarmic acid
  • Capobenic acid
  • dordaviprone (investigational drug)
  • Vitexin
  • Friluglanstat (investigational drug)
  • scorias spongiosa
  • Luseogliflozin
  • indoxacarb
  • prademagene zamikeracel
  • fidanacogene elaparvovec-dzkt
  • albifylline
  • idanpramine
  • araneus diadematus
  • Sulfamazone
  • Lycosa tarantula
  • malotilate
  • Ethacizine
  • Namilumab
  • Latrunculin B
  • stachyose
  • platinic oxide
  • iopronic acid
  • calcium chloride / potassium chloride/lactic acid/ sodium chloride/sodium hydroxide/sodium lactate solution
  • citric acid/ sodium bicarbonate/ sodium carbonate anhydrous
  • vadadustat
  • permethrin medical grade cis/trans isomers 25/75
  • lutetium, isotope of mass 177
  • human normal immunoglobulin
  • sacrosidase
  • apadamtase alfa, recombinant
  • acetyl hexapeptide-8 amide
  • pemivibart (Investigational)
  • govorestat
  • Zanidatamab
  • sotatеrcеpt
  • MV 140 vaccine
  • leuprorelin implant
  • cinchocaine hydrochloride/fluocortolone hexanoate/fluocortolone pivalate
  • Beautyberry
  • risedronate/calcium/vitamin D3
  • rhubarb extract/senna leaf/sulphur purified/wood charcoal
  • boric acid/kaolin/methyl salicylate/peppermint oil/thymol
  • docosahexaenoic acid/eicospentaenoic acid
  • aluminium hydroxide/magnesium hydroxide/simethicone
  • gentamicin/hydrocortisone
  • succinylcholine
  • sinefungin
  • letibotulinumtoxinA
  • coal tar/coconut oil/salicylic acid
  • camphor/camphor oil white/capsicum oleoresin /menthol/methyl salicylate
  • thioglycolic acid
  • acetic acid auricular
  • roluperidone
  • hydrocortisone/crotamiton topical
  • nystatin/chlorhexidine
  • aluminium chloride hexahydrate
  • ketoprofen topical
  • Chlormethine
  • podophyllotoxin
  • urea/lactic acid
  • autologous chondrocytes implant
  • afelimomab
  • gepotidacin
  • fludroxycortide
  • fentanyl transdermal
  • erythromycin/zinc acetate
  • dibotermin alfa powder
  • desferrioxamine mesilate
  • choline salicylate/magnesium salicylate
  • castor oil/peru balsam/trypsin
  • betamethasone/dexchlorpheniramine maleate
  • benzalkonium chloride solution/cetrimide
  • barzolvolimab
  • ascorbic acid / calcium laevulinate / nicotinamide / calcium pantothenate / calcium chloride / riboflavine / pyridoxine hydrochloride / thiamine hydrochloride
  • argipressin
  • arachis oil refined/chlorobutanol hemihydrate
  • arachis oil/eucalyptol/nutmeg oil/terpineol
  • ammonium chloride/diphenhydramine hydrochloride/levomenthol
  • amino acid mixture d / calcium chloride dihydrate / glucose monohydrate / glycine / magnesium chloride hexahydrate / olive oil / potassium chloride / sodium acetate trihydrate / sodium glycerophosphate pentahydrate / soya-bean oil
  • biotin/colecalciferol/copper (ii)sulfate dried/ cyanocobalamine/ dl-alpha tocopherol acetate/dibasic calcium phosphate anhydrous/folic acid/iron (ii)sulfate dried/ lecithin/ magnesium sulfate dried/ nicotinamide/ pyridoxine hydrochloride/ riboflavin
  • ampicillin sodium / cloxacillin sodium
  • undecylenic acid, undecylenate salts, zincundecate
  • omeprazole/sodium bicarbonate
  • efgartigimod alfa/hyaluronidase
  • xylometazoline/ipratropium
  • cefepime and enmetazobactam
  • isotonic sodium chloride
  • bee venom allergen injection
  • fentanyl intranasal
  • alglucosidase alfa
  • triprolidine/pseudoephedrine
  • pegademase bovine
  • castor oil and peru balsam
  • camphor/eucalyptus oil/menthol
  • oxyquinoline/sodium lauryl sulfate
  • somatorelin
  • menotrophin injection
  • menadiol
  • hylan g-f 20
  • cefepime and taniborbactum
  • water avens
  • camphor/menthol
  • acoramidis
  • elafibranor
  • arrowroot
  • miconazole nitrate/hydrocortisone
  • vildagliptin/metformin
  • dobesilic acid
  • aroxybutynin and atomoxetine
  • hygromycin
  • linvoseltamab
  • nemolizumab
  • aceprometazine
  • limaprost
  • oxazolam
  • trimegestone
  • teceleukin
  • beauty berry
  • dinotefuran
  • imiprothrin
  • transfluthrin
  • thymalfasin
  • technetium Tc 99m tilmanocept
  • glepaglutide
  • marstacimab
  • pixantrone
  • Andiroba
  • arabinoxylan
  • arenaria rubra
  • etripamil
  • jequirity
  • jiaogulan
  • dusquetide
  • rolipram
  • tradipitant
  • sinfungin
  • diclofenac/omeprazole
  • brinzolamide and timolol maleate
  • wormseed
  • wormwood
  • wood sorrel
  • carmellose sodium
  • ibandronic acid
  • cinnarizine and dimenhydrinate
  • ursodeoxycholic acid
  • rhubarb extract/salicylic acid
  • butamirate citrate
  • fumitory
  • taheebo
  • uva ursi
  • vervain
  • coleus
  • coltsfoot
  • crampbark
  • plantain
  • potassium nitrate and silver nitrate
  • gelsemium
  • gentian
  • glucomannan
  • walnut
  • meadowsweet
  • midomafetamine
  • pennyroyal
  • periwinkle
  • betony
  • bitter orange
  • bladderwrack
  • bloodroot
  • emu oil
  • garcinia
  • yellow dock
  • burdock
  • dehydroepiandrosterone
  • aucubin
  • jasmone
  • resacetophenone
  • ecamsule ditriethanolamine
  • feclobuzone
  • fenoprop triethanolamine
  • verdyl acetate
  • caffeic acid
  • cyclamen aldehyde
  • dicetyldimonium chloride
  • wogonin
  • impacarzine
  • laurylpyridinium chloride
  • stepronin
  • matrine
  • sakuranin
  • cannabichromene
  • sandalore
  • sabinene
  • oxypaeoniflora
  • ethylhexyl pelargonate
  • acrylonitrile
  • allyl alcohol
  • dipalmitoylethyl hydroxyethylmonium methosulfate
  • butidrine
  • clothiapine
  • propanediol dicaprylate
  • buchu
  • undecanol
  • enilconazole
  • xymenynic acid
  • angelica
  • nizubaglustat
  • resomelagon
  • ulecaciclib
  • apple cider vinegar
  • bacopa
  • barley grass
  • dandelion
  • deer velvet
  • dolomite
  • bugleweed
  • bupleurum
  • glyceryltrinitrate
  • pociredir
  • asnuciclib
  • actalycabtagene autoleucel
  • butantan–dengue vaccine
  • travoprost/timolol
  • furosemide/potassium chloride
  • amylamine
  • jaborandi
  • patritumab deruxtecan
  • jackfruit
  • sterculia
  • ascorbigen
  • ashitaba
  • androstenetrione
  • andrachne
  • cosibelimab
  • racecadotril
  • neomycin/chlorhexidine
  • octocog alfa
  • cetrimide
  • ispaghula husk
  • polyhexanide
  • octenidine
  • polygeline
  • heparinoid
  • jewelweed
  • boldo
  • anizatrectinib
  • alpinia
  • henbane
  • cynanchum vincetoxicum root and sulfur
  • boditrectinib
  • izumerogant
  • zavondemstat
  • abuta
  • fadogia agrestis
  • fly agaric mushroom
  • meptazinol
  • methoxyflurane
  • tramadol/dexketoprofen
  • betaine/polyhexanide
  • filgotinib
  • inosine acedoben dimepranol
  • alverine citrate
  • hyoscine butylbromide
  • senna+ ispaghula
  • cabbage palm
  • cajeput oil
  • calanus oil
  • calamint
  • canada balsam
  • carnosine
  • alverine citrate/simeticone
  • dihydroartemisinin/piperaquine
  • mebeverine/ispaghula
  • calcipotriol
  • tacalcitol
  • triethyl citrate/ethyl linoleate
  • sodium dilauramidoglutamide lysine
  • fazamorexant
  • avibactam tomilopil and ceftibuten
  • drostanolone
  • tigilanol tiglate
  • isorhynchophylline
  • rhynchophylline
  • crisugabalin
  • epigallocatechin gallate
  • clomocycline
  • corynoxeine
  • isocorynoxeine
  • Culmerciclib
  • Neladenoson
  • ambrein
  • hexylcaine
  • phensuximide
  • resencatinib (investigational)
  • rolusafine
  • pumecitinib
  • arhalofenic acid
  • berdazimer sodium
  • benzquinamide
  • clidinium
  • sulfametopyrazine
  • fulzerasib (Investigational Drug)
  • rovadicitinib (Investigational Drug)
  • Upleganan (Investigational Drug)
  • menthyl ethylamido oxalate
  • quaternium-90 montmorillonite
  • unecritinib (investigational drug)
  • etohexadiol
  • guaiol
  • proximadiol
  • verdinexor
  • sofnobrutinib
  • talbutal
  • ethoxzolamide
  • propiomazine
  • enprofylline
  • phenmetrazine
  • merigolix
  • pralurbactam
  • neracorvir
  • vonifimod
  • apaziquone hydroquinone
  • darizmetinib
  • zandelisib
  • xininurad
  • ritivixibat
  • amiselimod phosphate (investigational drug)
  • emzeltrectinib (investigational drug)
  • ficonalkib
  • cinalukast
  • ulobetasol