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Brand Name :
N/A
Synonyms :
Maranhao Jaborandi, Juarandi, Pilocarpus Jaborandi, Pilocarpus microphyllus
Class :
Vitamins and supplements
Dosage Forms & Strengths
Limited information available
Off-label:
Apply to the hair twice a week
Off-label:
Apply to the hair twice a week
Tincture
100 mL
200 mL
500 mL
Refer to the adult dosing
Actions and Spectrum:
Actions:
The parasympathetic nervous system is activated by jaborandi, which leads to a rise in the production of bodily fluids such mucus, sweat, tears, and saliva.
Spectrum:
Jaborandi’s anti-inflammatory qualities may help reduce inflammation while also increasing saliva production, which supports xerostomia.
Limited information available
Black Box Warning
Limited data is available
Contraindication/Caution:
Contraindications
Hypersensitivity
Cautions
Renal impairment
Hepatic impairment
Drug interactions
Pregnancy
Breastfeeding
Pregnancy/Lactation:
Pregnancy consideration:
No data is available regarding the administration of the drug during pregnancy.
Breastfeeding warnings:
No data is available regarding the excretion of drug in breast milk.
Pregnancy category:
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: There was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: Adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology:
Jaborandi contains the alkaloid pilocarpine with significant pharmacological effects.
Pharmacodynamics
The parasympathetic nervous system is activated by jaborandi, which leads to a rise in the production of bodily fluids such mucus, sweat, tears, and saliva.
Pharmacokinetics:
Limited data is available
Administration:
Jaborandi is administered orally, topically & for ophthalmic purposes.
Patient information leaflet
Generic Name: jaborandi
Pronounced: juh-boh-RAN-dee
Why do we use jaborandi?
It lowers eye pressure and is used in eye drops and conventional medicine to treat glaucoma. Formulations containing pilocarpine are used to stimulate saliva production and treat dry mouth.