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Brand Name :
NEUROPLEX-G
Synonyms :
l-glutamic acid /vitamin B complex
Class :
Vitamins/Minerals
Dosage forms and strengths
NEUROPLEX-G syrup
niacinamide 30 mg/5 mL
vitamin B12 5 mcg
vitamin B6 1.5 mg
vitamin B1 4.5 mg
l-glutamic acid 100 mg
It should be taken as per the physician’s advice
Not indicated
Refer adult dosing
Actions and Spectrum:
Action: l-glutamic acid, in combination with vitamin B complex, contributes to various metabolic processes supporting energy production, nervous system function, and synthesis of neurotransmitters.
The collaborative action of l-glutamic acid and vitamin B complex enhances the overall cellular and neurological health, playing a pivotal role in maintaining physiological balance.
Frequency not defined
Uncoordinated body movements
Tiredness
Sleepiness
Dizziness
Black Box Warning:
None
Contraindication/Caution:
Pre-existing medical conditions: Caution is advised in pre-existing medical conditions like renal impairment or certain neurological disorders before taking the combination of l-glutamic acid and vitamin B complex.
Pregnancy and breastfeeding: Pregnant women should seek medical advice before initiating supplementation with this combination.
Pregnancy warnings:
Pregnancy category: N/A
Lactation: Excreted into human milk is unknown
Pregnancy Categories:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
Category B: There were a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology: l-glutamic acid is an amino acid that serves as a neurotransmitter and plays various roles in various metabolic pathways.
The vitamin B complex is crucial for energy production, nervous system function, and the synthesis of neurotransmitters.
Pharmacodynamics:
Together, l-glutamic acid and vitamin B complex contribute synergistically to cellular metabolism, supporting the central nervous system and promoting overall physiological well-being. Their combined pharmacological effects encompass neurotransmission facilitation, energy metabolism enhancement, and active participation in biochemical reactions vital for cellular function.
Pharmacokinetics:
Absorption
l-glutamic acid is absorbed in the gastrointestinal tract, while vitamin B is absorbed through various mechanisms in the small intestine.
Distribution
Once absorbed, l-glutamic acid and vitamin B are distributed throughout the body via the bloodstream, reaching target tissues.
Metabolism
l-glutamic acid undergoes metabolism in various tissues participating in neurotransmitter synthesis. vitamin B undergoes metabolic transformations, contributing to energy production and various biochemical pathways.
Excretion and Elimination
l-glutamic acid is metabolized and eliminated, and excess vitamin B is often excreted through urine.
Administration:
The route of administration is oral.
The specific dosage and administration regimen depend on various factors, including individual health conditions and nutritional requirements.
Patient information leaflet
Generic Name: l-glutamic acid /vitamin B complex
Why do we use l-glutamic acid /vitamin B complex?
l-glutamic acid and vitamin B collectively support cellular metabolism, promoting overall cellular health and function.
The combination is used as a dietary supplement to address deficiencies and enhance overall nutritional intake.