lurasidone

DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:   

>10%   

Nausea (9-13%)   

Insomnia (7-11%)   

Extrapyramidal disorder (6-22%)   

Parkinsonism (6-17%)   

Somnolence (15-26%)   

Akathisia (6-22%)   

Fasting glucose increased (10-14%)   

1-10%   

Vomiting (6-8%)   

Agitation (3-10%)   

Anxiety (3-8%)   

Dyspepsia (5-8%)   

Back pain (2-4%)   

Restlessness (3%)   

Hypertension   

Rash   

Dizziness (4-6%)   

Fatigue (4%)   

Elevated serum creatinine (1-7.2%)   

Dystonia (5%)   

Pruritus   

CPK increased   

  

Pregnancy warnings:     

AU TGA pregnancy category: B1 

US FDA pregnancy category: N/A 

Lactation: 

Excreted into human milk is UNknown 

Pregnancy Categories:       

Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.       

Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women       

Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women       

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.       

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.       

Category N: There is no data available for the drug under this category 

  

Patient Information Leaflet   

Generic Name: lurasidone 

Why do we use lurasidone? 

lurasidone are an atypical antipsychotic used to treat Schizophrenia and bipolar disorder.