Evaluating Match Rates Between OASIS Assessments and Medicare Claims Data
April 4, 2026
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Brand Name :
FYBOGEL MEBEVERINE effervescent granules, Morease-I
Synonyms :
Mebeverina, mebeverine, Mebeverinum/Psyllium, Psyllium husk
Class :
Neuropsychiatric agent, Muscarinic cholinergic receptor antagonist, Antispasmodic, smooth muscle relaxant, Muscarinic acetylcholine receptor antagonist/Crude drug, Plantago seed, Drug for dampness, Diuretic drug, Antitussive, Expectorant, Hypoglycemic, Laxative;
Brand Name :
FYBOGEL MEBEVERINE effervescent granules, Morease-I
Synonyms :
Mebeverina, mebeverine, Mebeverinum/Psyllium, Psyllium husk
Class :
Neuropsychiatric agent, Muscarinic cholinergic receptor antagonist, Antispasmodic, smooth muscle relaxant, Muscarinic acetylcholine receptor antagonist/Crude drug, Plantago seed, Drug for dampness, Diuretic drug, Antitussive, Expectorant, Hypoglycemic, Laxative;
Dosage Forms & Strengths
Powder (effervescent granules)
135 mg/3.5 mg
Dosage Forms & Strengths
Capsule (effervescent granules)
135 mg/3.5 mg
Refer to the adult dosing
Actions and Spectrum:
Actions:
People with irritable bowel syndrome take two medicines. One is Mebeverine, which calms the intestine muscles – this stops cramping pains. The other, Ispaghula, soaks up water and bulks out bowel motions, making them softer and simpler to pass through the body’s digestive system.
Spectrum:
ISPAGHULA HUSK+MEBEVERINE treats symptoms like stomach ache, cramps, bloating, and irregular bowel movements. This medication helps with IBS, an inflammatory gut condition. It works by combining mebeverine, which stops muscle spasms, and ispaghula, a laxative. Mebeverine blocks signals in muscles, preventing contractions and easing cramps, bloating, and pain from spasms. Meanwhile, ispaghula absorbs water, softening stools for easier passing.
Frequency not defined
Dizziness
Insomnia
Slow heart rate (pulse)
Bloating
Loss of appetite
Headache
Stomach Upset
Skin rash
Indigestion
Constipation
Hypersensitivity
Urticaria
Contraindication/Caution:
Contraindications
Cautions
Pregnancy consideration:
No data is available regarding the administration of the drug during pregnancy.
Breastfeeding warnings:
No data is available regarding the excretion of drug in breast milk.
Pregnancy category:
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology:
Mebeverine reduces painful muscle contractions in the tummy, easing IBS troubles. The husk of psyllium seeds soaks up liquid – this bulks up poo. Bigger, softer stools help when constipated. This also settles the digestive system.
Pharmacodynamics:
Mebeverine reduces stomach cramps by preventing muscle spasms. These spasms cause discomfort, bloating and cramps by interfering with muscle signals. Ispaghula works differently: it soaks up water in your intestines. This forms a gel, making stools softer and bigger. As a result, it becomes easier to have bowel movements.
Pharmacokinetics:
Distribution
Mebeverine is a drug that treats intestinal problems. Many mebeverine particles, around 76%, bind to proteins in blood. This means most of the drug links with proteins circulating through your body. The attaching changes how mebeverine moves through and leaves your system. Its effects and behaviors are altered by binding to these proteins. Mebeverine’s effects throughout the body are impacted by this widespread protein bonding.
Administration:
Consume one packet of Fybogel mebeverine granules 30 minutes prior to your morning meal. Repeat this process before dinner. If needed, take a third packet preceding lunch. Mix each packet thoroughly with 150ml (a quarter pint) of cool water and drink immediately after stirring. Ensure you hydrate adequately throughout the day, but avoid ingesting Fybogel mebeverine right before bedtime if you’re 12 or older.
Patient information leaflet
Generic Name: mebeverine/ispaghula
Pronounced: meh-BEV-uh-reen/PAGH-yuh-luh
Why do we use mebeverine/ispaghula?
Mebeverine relieves IBS symptoms like belly pain and bloating by relaxing gut muscles, stopping spasms and discomfort. Ispaghula, a fiber, fights constipation by soaking up water in the intestines, making stools bigger and easier to pass. Doctors sometimes recommend both for better IBS management. Mebeverine stops cramps, while ispaghula helps regulate bowel movements. Together, they ease IBS symptoms like pain and irregular bowel habits.
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