menthyl ethylamido oxalate

Action and Spectrum

Actions and Spectrum: 

Actions: 

Menthyl ethylamido oxalate stimulates nerve endings, creating a perceived cooling effect on the skin and adjusts skin sensations, making it ideal for lotions, creams, and balms. 

Spectrum: 

Frescolat X-cool, derived from synthetic menthol, is a potent coolant offering intense freshness. It boasts a high safety profile, works effectively with mucosa, and is gentle on the skin. 

Drug Interaction

Adverse Reaction

Frequency not defined 

Skin irritation 

Sun sensitivity 

Eye irritation 

Allergic reactions 

Black Box Warning

Black Box Warning: 

Be careful when using products with menthyl ethylamido oxalate to avoid irritating sensitive areas like the eyes. 

Contraindication / Caution

Contraindication/Caution: 

Contraindications 

Hypersensitivity 

Cautions 

Liver impairment 

Sun sensitivity 

Skin irritation 

Allergic reactions 

Pregnancy 

Eyes irritation 

Breastfeeding 

Renal impairment 

Pregnancy / Lactation

Pregnancy consideration: 

No data is available regarding the administration of the drug during pregnancy. 

Breastfeeding warnings: 

No data is available regarding the excretion of drug in breast milk. 

Pregnancy category: 

Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester. 

<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. 

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: No data is available for the drug under this category. 

Pharmacology

Pharmacology: 

Methyl ethylamido oxalate, from menthol, improves sensory experience in cosmetics by cooling the skin. It activates TRP channels, altering skin perception, mainly in lotions and creams. 

Pharmacodynamics: 

Menthyl ethylamido oxalate creates a cooling feeling by interacting with skin receptors, derived from menthol, used in skincare for its sensory effects, activating TRP channels when applied. 

Pharmacokinetics: 

Limited data is available 

Adminstartion

Administration: 

Apply skincare products containing menthyl ethylamido oxalate directly onto the skin, spreading them over the desired area. 

Patient Information Leaflet

Patient information leaflet 

Generic Name: menthyl ethylamido oxalate 

Pronounced: MEN-thil ETH-il-AM-i-do OK-suh-late 

Why do we use menthyl ethylamido oxalate? 

Menthyl ethylamido oxalate is used in skincare and cosmetics for its cooling effect, commonly found in lotions, creams, and balms for a refreshing sensation.