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mibefradil

Brand Name :

Posicor

(United States) [DSC]
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Brand Name :

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Synonyms :

mibefradil

Class :

Calcium Antagonists





No data available for drug.

Actions and Spectrum: 

Action: mibefradil selectively blocks T-type calcium channels in the heart and peripheral blood vessels. Doing so reduces the influx of calcium ions into these cells, leading to vasodilation (widening of blood vessels) and decreased cardiac contractility. The net effect is a reduction in blood pressure and a decrease in the workload on the heart, making it an effective antihypertensive and antianginal agent. 

Spectrum: mibefradil was initially approved to treat hypertension and chronic stable angina. Its unique mechanism of action, particularly its inhibition of T-type calcium channels, made it a promising alternative to other calcium channel blockers. 

 

 

DRUG INTERACTION

mibefradil

&

  • metenolone
  • reproterol
  • rebamipide
  • mephenoxalone
  • metandienone
  • furosemide/spironolactone
  • hydroxycarbamide
  • tenonitrozole
  • fenoverine
  • fenquizone
  • tiapride
  • tibolone
  • furazolidone
  • furosemide & amiloride
  • fosfestrol
  • fluclorolone
  • flubendazole
  • tertatolol
  • tetracosactide
  • tetryzoline
  • tolciclate
  • trapidil
  • troxipide
  • temoporfin
  • telbivudine
  • teprenone
  • hexamidine
  • mebhydrolin
  • mepartricin
  • fencamfamin
  • medazepam
  • theodrenaline
  • thiamazole
  • thiocolchicoside
  • psilocybin
  • veralipride
  • pyritinol
  • opipramol
  • oprelvekin
  • betamethasone + gentamicin
  • betamethasone + neomycin
  • betamethasone + salicylic acid
  • oxedrine
  • bopindolol
  • orgotein (investigational)
  • oxaceprol
  • ormeloxifene
  • bevantolol
  • bifemelane
  • clebopride
  • demoxytocin
  • cicletanine
  • cefsulodin
  • chlortalidon
  • sisomicin
  • somatrem
  • carbazochrome
  • caroverine
  • cathine
  • ipriflavone
  • isepamicin
  • silymarin
  • simethicone
  • sermorelin
  • diloxanide
  • dimethindene
  • diosmin/hesperidin
  • calamine
  • canrenone
  • captodiame
  • imidapril
  • cefetamet
  • cefodizime
  • cefoperazone + sulbactam
  • ivermectin + albendazole
  • serrapeptase
  • bromisoval
  • beraprost
  • pridinol
  • proglumide
  • bamipine
  • barnidipine
  • bamifylline
  • benzbromarone
  • betamethasone/fusidic acid
  • para-chlorophenol
  • pantethine
  • nomifensine
  • pemoline
  • parnaparin
  • pentolinium
  • nialamide
  • novobiocin
  • nicergoline
  • octocrylene
  • octisalate
  • oftasceine
  • oxolamine
  • oxyphencyclimine
  • penfluridol
  • pentoxyverine
  • phenoxymethylpenicillin
  • picloxydine
  • pilsicainide hydrochloride
  • piperazine
  • pirarubicin
  • policresulen
  • prifinium bromide
  • prethcamide
  • pristinamycin
  • pirenzepine
  • piribedil
  • pimethixene
  • pargyline
  • phosphatidyl choline
  • phthalylsulfathiazole
  • phytomenadione
  • pranlukast
  • pinazepam
  • oxyphenonium
  • noxytiolin
  • periciazine
  • pethidine
  • phenindamine
  • histidine
  • isoleucine
  • proline
  • lauric acid
  • lymecycline
  • hypromellose
  • abiraterone acetate and niraparib
  • ichthammol
  • levamisole
  • naftazone
  • nefopam
  • oxprenolol
  • oxybuprocaine
  • elranatamab-bcmm
  • lapyrium
  • isoaminile
  • iotrolan
  • mazindol
  • masoprocol
  • lypressin
  • meradimate
  • molsidomine
  • monobenzone
  • mequinol/gluconolactone/ lactobionic acid/ arbutin
  • medifoxamine
  • mebutamate
  • metergoline
  • methantheline
  • methdilazine
  • metocurine
  • micronomicin
  • metaraminol
  • mephenesin
  • menadione
  • medrysone
  • metixene
  • levobetaxolol
  • guaiacol glycerol ether
  • eucalyptol
  • sodium tetradecyl sulfate
  • sugammadex
  • carbetocin
  • certoparin
  • chlorcyclizine/pseudoephedrine
  • cephapirin
  • indecainide
  • iobitridol
  • iomeprol
  • chlorphenesin
  • msud analog
  • msud maxamum
  • iceland moss
  • glutethimide
  • hexachlorophene
  • haloprogin
  • deferoxamine
  • ethchlorvynol
  • dexpanthenol topical
  • etilefrine
  • deslanoside
  • carbocromen
  • diazolidinylurea
  • dibenzepin
  • etofamide
  • guanoxan
  • halazepam
  • guanadrel sulfate
  • dapiprazole
  • soapwort
  • debrisoquine
  • l-tryptophan
  • chlormerodrin
  • chlorquinaldol
  • cetrimonium
  • carbocisteine
  • chlorcyclizine/codeine
  • technetium Tc-99m tetrofosmin
  • technetium Tc-99m disofenin
  • technetium Tc-99m gluceptate
  • technetium Tc-99m labeled red blood cells
  • amylmetacresol/dextromethorphan hydrobromide
  • anileridine phosphate
  • pyrethrins
  • pyrantel pamoate
  • quinagolide
  • spiramycin
  • standard hyperkalemic cardioplegia solution
  • technetium tc-99m mertiatide
  • technetium tc-99m medronate
  • bemotrizinol / bisoctrizole
  • benfotiamine
  • bemotrizinol + titanium dioxide + zinc oxide
  • technetium Tc-99m oxidronate
  • technetium Tc-99m pentetate
  • technetium Tc-99m pyrophosphate
  • benziodarone
  • octinoxate/bisoctrizole
  • bicisate dihydrochloride
  • technetium Tc-99m bicisate
  • norelgestromin/ethinyl estradiol
  • norgestimate/ethinyl estradiol
  • ximelagatran (investigational)
  • xamoterol
  • trioxsalen
  • poly-urea urethane
  • rilmenidine
  • pemirolast
  • oxitriptan
  • beclomethasone, intranasal
  • thimerosal
  • camphor gel
  • camphor
  • mumps virus vaccine, live
  • rubella virus vaccine, live
  • aluminum chloride (dental)
  • alum irrigation
  • framycetin, phenylephrine, and gramicidin
  • ombitasvir, paritaprevir, ritonavir, and dasabuvir
  • olipudase alfa
  • etonogestrel/ethinyl estradiol
  • mycophenolate
  • fluoroestradiol F 18
  • donor organ cardioplegia solution
  • fluciclovine F 18
  • fusidic acid (ophthalmic)
  • fusidic acid and hydrocortisone
  • framycetin, dexamethasone, and gramicidin
  • fludeoxyglucose F-18
  • fluorouracil/salicylic acid
  • indium In-111 oxyquinoline
  • indium In-111 pentetreotide
  • indium In-111 capromab pendetide
  • lusutrombopag
  • mitomycin (ophthalmic)
  • mifepristone and misoprostol
  • minoxidil (systemic)
  • methyl aminolevulinate (topical)
  • methyl folate, methylcobalamin, and acetylcysteine
  • ciclesonide/formoterol/tiotropium
  • nedocromil (Oral Inhalation)
  • batefenterol (Investigational)
  • neostigmine and glycopyrrolate
  • nepafenac ophthalmic
  • netupitant/palonosetron
  • meperidine and promethazine
  • mepivacaine and levonordefrin
  • maltodextrin
  • medical cannabis
  • medium chain triglycerides
  • mometasone/glycopyrrolate (glycopyrronium)/ indacaterol
  • moxifloxacin ophthalmic
  • neomycin/fluocinolone
  • nadroparin
  • iodine I-125 iothalamate
  • amikacin liposome (oral inhalation)
  • bupivacaine liposome
  • natamycin
  • lopinavir and ritonavir
  • lysine
  • macitentan and tadalafil
  • mitomycin pyelocalyceal
  • moclobemide
  • mometasone and indacaterol
  • efinaconazole
  • blue-green algae
  • indocyanine green
  • follitropin beta
  • lumasiran
  • glycerin/lidocaine
  • edrophonium/atropine
  • indigo carmine
  • lutropin alfa
  • instant glucose/intravenous dextrose
  • iobenguane I-123
  • ixekizumab
  • isosulfan blue dye
  • levofloxacin ophthalmic
  • levonorgestrel oral/ferrous bisglycinate/ ethinylestradiol
  • ethinyl estradiol/levonorgestrel transdermal
  • hydroquinone
  • hydroxypropyl methylcellulose
  • icodextrin
  • lipid emulsion (soybean, medium-chain triglyceride, olive, and fish oils; [SMOF])
  • iodinated I 125 albumin
  • iodinated I 131 albumin
  • lipid emulsion (plant oil-based)
  • levonorgestrel intrauterine
  • levonorgestrel oral/ethinyl estradiol
  • lactic acid and sodium-PCA
  • lactated Ringer solution
  • ketotifen (systemic)
  • lanolin
  • leuprolide and norethindrone
  • levodopa and benserazide
  • gonadorelin acetate
  • hemodialysis solutions
  • nirsevimab-alip
  • gentian violet
  • gallium ga-68 dotatate
  • fusidic acid and betamethasone
  • gallium citrate Ga-67
  • gadopentetate dimeglumine
  • gadofosveset
  • follitropin delta
  • follitropin alfa and lutropin alfa
  • follitropin alfa
  • rocatinlimab
  • grass pollens allergen extract
  • flotufolastat F18
  • fluorescein ophthalmic
  • barium
  • balanced salt solution
  • air polymer type A intrauterine device
  • clodronate
  • bentoquatam
  • clobetasone
  • alfacalcidol
  • citric acid/glucono-delta-lactone/magnesium carbonate
  • benzoin
  • desirudin
  • immune globulin IV (IGIV)
  • dequalinium
  • pseudoephedrine/desloratadine
  • clofedanol
  • cyproterone and ethinyl estradiol
  • dextranomer and hyaluronic acid or derivatives
  • diatrizoate meglumine and diatrizoate sodium
  • glucosamine sulfate, chondroitin sulfate and Msm
  • squill
  • gotu kola
  • blessed thistle
  • bitter melon
  • apraclonidine
  • chlophedianol/dexbrompheniramine/pseudoephedrine
  • wild jujube
  • chitosan
  • cilazapril/hydrochlorothiazide
  • dexbrompheniramine and phenylephrine
  • diethylene triamine penta-acetic acid
  • dexchlorpheniramine and pseudoephedrine
  • lily of the valley
  • diflucortolone
  • corydalis
  • lemon balm
  • MSM
  • calcium polystyrene sulfonate
  • caprylidene
  • peppermint oil
  • efavirenz/lamivudine/tenofovir DF
  • emtricitabine/tenofovir DF /efavirenz
  • dutasteride/tamsulosin
  • milk thistle
  • centaury
  • horseweed
  • lycopus
  • agrimony
  • alfalfa
  • kava
  • cetrorelix
  • cetylpyridinium
  • chlophedianol and dexbrompheniramine
  • betahistine
  • choline C-11
  • boric acid vaginal suppository
  • aluminum acetate
  • aluminum chloride hexahydrate
  • 14-C urea breath test
  • absorbable collagen
  • valoctocogene roxaparvovec-rvox
  • amlodipine and celecoxib
  • aspirin and omeprazole
  • azilsartan and chlorthalidone
  • landiolol (Pending FDA approval)
  • isosorbide dinitrate/hydralazine
  • losartan/hydrochorothiazide
  • udenafil
  • dextromethorphan/quinidine
  • onasemnogene abeparvovec
  • orphenadrine/aspirin/caffeine
  • trace elements
  • sodium phenylbutyrate/ taurursodiol
  • fish oil triglycerides
  • infant formula
  • glutamine
  • chloroquine phosphate
  • afatinib
  • quinidine gluconate
  • methylergonovine
  • prothrombin complex concentrate, human
  • BCG intravesical live
  • capivasertib
  • cedazuridine
  • carbonyl iron
  • iron dextran complex
  • lovotibeglogene autotemcel (FDA Approval Pending)
  • sodium benzoate/sodium phenylacetate
  • mineral oil otic
  • zolmitriptan transdermal
  • midazolam intranasal
  • fosinopril/hydrochlorothiazide
  • caplacizumab
  • arginine
  • sodium phenylbutyrate
  • meloxicam/rizatriptan
  • manganese
  • acetaminophen/pamabrom/pyridoxine
  • varicella zoster immune globulin, human
  • amitriptyline/perphenazine
  • narsoplimab (Pending FDA Approval)
  • amlodipine/perindopril
  • imiglucerase
  • canagliflozin/metformin
  • tafamidis meglumine
  • somatrogon-ghla
  • glimepiride/rosiglitazone
  • becaplermin
  • lithium
  • loxapine inhaled
  • nicotine transdermal
  • tixagevimab and cilgavimab (Investigational)
  • muromonab CD3
  • ansuvimab
  • coal tar bath products
  • fibrin sealant
  • arimoclomol (FDA Approval Pending)
  • varenicline intranasal
  • aducanumab
  • oxycodone/naloxone
  • ritlecitinib
  • sodium polystyrene sulfonate
  • calcipotriene/betamethasone
  • calcium hydroxylapatite
  • cantharidin topical
  • doxepin cream
  • clocortolone
  • formaldehyde topical
  • sodium sulfide topical
  • collagenase
  • selegiline transdermal
  • foscarbidopa/foslevodopa (FDA approval pending)
  • saxagliptin/metformin
  • linagliptin/metformin
  • linzagolix (FDA approval pending)
  • efgartigimod/hyaluronidase SC
  • elamipretide (Pending FDA approval)
  • rozanolixizumab
  • diazoxide
  • glimepiride/pioglitazone
  • cipaglucosidase alfa
  • dihydroergotamine intranasal
  • delandistrogene moxeparvovec
  • beremagene geperpavec
  • hyaluronic acid and derivatives
  • hyaluronic acid, non-animal stabilized
  • eplontersen (FDA Approval Pending)
  • nitric oxide gas
  • sodium phenylbutyrate and taurursodiol
  • treprostinil SC
  • viltolarsen
  • albuterol/ipratropium
  • budesonide inhaled
  • budesonide rectal
  • palovarotene (FDA Approval Pending)
  • sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycol
  • amino acids mixture
  • aminobenzoate potassium
  • elivaldogene autotemcel
  • naproxen and sumatriptan
  • sumatriptan intranasal
  • alglucerase
  • metformin/rosiglitazone
  • ertugliflozin/metformin
  • elosulfase alfa
  • calcium carbonate/magnesium hydroxide
  • starch suppository
  • abicipar pegol (FDA Approval Pending)
  • riboflavin 5′-phosphate ophthalmic
  • povidone ophthalmic
  • glycerin oropharyngeal
  • dimethicone topical
  • menthol topical, dimethicone topical
  • pramoxine topical, menthol topical and dimethicone topical
  • phosphorated carbohydrate
  • brilliant blue G ophthalmic
  • brolucizumab intravitreal
  • purified water, ophthalmic
  • hydroxyethyl cellulose ophthalmic
  • ranibizumab intravitreal implant
  • sodium chloride hypertonic, ophthalmic 
  • cetirizine ophthalmic
  • phentolamine ophthalmic (FDA Approval Pending)
  • ganciclovir ophthalmic
  • triamcinolone intravitreal
  • ocriplasmin intravitreal
  • atoltivimab/maftivimab/odesivimab
  • pegcetacoplan intravitreal
  • triamcinolone acetonide extended-release injectable suspension
  • tobramycin/loteprednol ophthalmic
  • 2-octyl cyanoacrylate
  • vitamins A & D topical
  • diphenhydramine/allantoin topical
  • pyrethrins/piperonyl butoxide
  • lodoxamide ophthalmic
  • obeticholic acid
  • fluocinolone intravitreal implant
  • sincalide
  • linaclotide
  • nedocromil ophthalmic
  • cysteamine ophthalmic
  • avacincaptad pegol intravitreal
  • azelastine ophthalmic
  • bacitracin ophthalmic
  • propylene glycol ophthalmic
  • rimexolone ophthalmic
  • metoclopramide intranasal
  • mirikizumab (FDA approval pending)
  • netarsudil ophthalmic
  • cenegermin
  • dexamethasone ophthalmic insert
  • prednisolone ophthalmic
  • phenylephrine and cocoa butter rectal
  • phenylephrine and witch hazel topical
  • phenylephrine, pramoxine, glycerin and petrolatum rectal
  • bisacodyl rectal
  • aluminum hydroxide/magnesium carbonate
  • aluminum hydroxide/magnesium hydroxide
  • hyoscyamine spray
  • methenamine/methylene blue/ hyoscyamine/ sodium phosphate monobasic/ phenyl salicylate
  • phenylephrine
  • chlorophyll
  • castor oil
  • cholic acid
  • phenol oropharyngeal
  • articaine/epinephrine
  • antithymocyte globulin equine
  • aluminum hydroxide/magnesium trisilicate
  • methenamine/hyoscyamine
  • hydrocortisone topical/pramoxine topical 
  • sodium fluoride topical
  • mesna
  • C1 esterase inhibitor recombinant
  • menthol and pectin
  • menthol oropharyngeal
  • pectin oropharyngeal
  • gepirone
  • Goldenseal
  • polyethylene glycol and electrolytes
  • polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid
  • brompheniramine/pseudoephedrine/dextromethorphan
  • brompheniramine phenylephrine
  • acetaminophen/doxylamine/phenylephrine
  • doxylamine/acetaminophen/pseudoephedrine/dextromethorphan
  • acetaminophen/doxylamine/dextromethorphan
  • acetaminophen/doxylamine/dextromethorphan/phenylephrine
  • eslicarbazepine
  • fluticasone and salmeterol
  • codeine, acetaminophen, butalbital and caffeine
  • codeine, chlorpheniramine and phenylephrine
  • iodine
  • povidone iodine
  • butalbital/aspirin/caffeine/codeine
  • polyethylene glycol 400/propylene glycol ophthalmic 
  • pegvaliase
  • amivantamab
  • iopamidol
  • codeine and pseudoephedrine
  • emtricitabine, rilpivirine, tenofovir DF
  • penicillin G aqueous
  • miconazole topical
  • miconazole vaginal
  • ciprofloxacin inhaled (Pending FDA approval)
  • ceftazidime/avibactam
  • ceftolozane/​tazobactam
  • aztreonam inhalation
  • amphotericin B cholesteryl sulfate
  • miconazole oral
  • elvitegravir/cobicistat/emtricitabine/tenofovir DF
  • isavuconazonium sulfate
  • dapivirine intravaginal (FDA Approval Pending)
  • lamivudine/raltegravir
  • codeine/triprolidine/pseudoephedrine
  • cadexomer iodine
  • brompheniramine/pseudoephedrine
  • codeine/acetaminophen
  • codeine/guaifenesin
  • beclomethasone inhaled
  • epoetin beta/methoxy polyethylene glycol
  • voreloxin(Orphan Drug)
  • rociletinib
  • pitcher plant
  • phosphatidylserine
  • telotristat ethyl
  • copper CU 64 dotatate
  • urea topical
  • exenatide subdermal implant
  • asenapine transdermal
  • ethiodized oil
  • urea oral
  • miglustat
  • acalisib(Investigational)
  • acetophenazine
  • guggul
  • aceneuramic acid
  • mestranol/norethindrone
  • reishi
  • lactitol
  • vonoprazan fumarate
  • motherwort
  • silver nitrate
  • salicylic acid/sulfur shampoo
  • salicylic acid topical
  • ketorolac ophthalmic
  • ketoconazole topical
  • Japanese encephalitis virus vaccine
  • dibucaine topical ointment
  • ketorolac intranasal
  • ketorolac/phenylephrine ophthalmic
  • rotavirus oral vaccine, live
  • guarana
  • hops
  • krill oil
  • salicylic acid/coal tar shampoo
  • sufentanil SL
  • pancrelipase
  • passion flower
  • pepdite one plus
  • nivolumab and relatlimab
  • relatlimab (Pending FDA Approval)
  • benzalkonium chloride/benzocaine
  • ketotifen, drug-eluting contact lens
  • calcitriol topical
  • oxymetazoline topical
  • alclometasone topical
  • capsaicin topical
  • diclofenac/misoprostol
  • diclofenac ophthalmic
  • diclofenac topical
  • pramoxine/calamine topical
  • veverimer
  • tolazoline
  • olopatadine ophthalmic
  • lutetium lu 177-dota-tate
  • lutetium lu 177 vipivotide tetraxetan
  • strontium 89 chloride
  • interferon alfa n3
  • lutetium Lu 177- Diethylenetriamine Pentaacetic acid-omburtamab (FDA Approval Pending)
  • samarium sm 153 lexidronam
  • cytomegalovirus immune globulin (CMV IG)
  • antithymocyte globulin rabbit
  • inolimomab (Pending FDA Approval)
  • olopatadine intranasal
  • olopatadine intranasal/​mometasone, intranasal
  • benzocaine/butamben/tetracaine topical
  • antipyrine/benzocaine/phenylephrine
  • dyclonine/menthol
  • surufatinib
  • fruquintinib
  • tepotinib 
  • dostarlimab
  • hepatitis B immune globulin (HBIG)
  • remestemcel-L
  • benzocaine/menthol oropharyngeal
  • interferon beta 1b
  • tetracaine/oxymetazoline intranasal
  • benzocaine oropharyngeal
  • benzalkonium chloride/menthol/petrolatum topical
  • inamrinone
  • alpha 1 proteinase inhibitor
  • potassium bicarbonate/potassium citrate
  • potassium phosphate/sodium acid phosphate
  • asparaginase Erwinia chrysanthemi recombinant
  • motixafortide
  • pegloticase
  • etesevimab
  • Rho(D) immune globulin
  • tetanus immune globulin (TIG)
  • reltecimod (pending FDA approval)
  • avasopasem
  • trimethoprim/polymyxin B ophthalmic
  • naphazoline ophthalmic
  • sulfacetamide topical
  • sirolimus intravitreal (pending FDA approval)
  • sirolimus protein bound
  • sirolimus topical
  • glycopyrronium tosylate topical
  • sofpironium
  • olmesartan, amlodipine and hydrochlorothiazide
  • dovitinib (Pending FDA Approval)
  • epinephrine inhaled
  • quizartinib (Pending FDA Approval)
  • ranibizumab intravitreal injection
  • sodium hyaluronate
  • bacitracin and lidocaine topical
  • brimonidine topical
  • benzoyl peroxide and tretinoin topical
  • talquetamab
  • betrixaban
  • acetaminophen/caffeine/pyrilamine
  • fentanyl transmucosal
  • bacitracin topical
  • buprenorphine,long-acting injection
  • buprenorphine buccal
  • nalmefene intranasal
  • sulbactam/durlobactam
  • metronidazole topical 
  • daratumumab/hyaluronidase
  • glofitamab
  • rituximab-hyaluronidase
  • drospirenone/ethinyl estradiol/levomefolate
  • loncastuximab tesirine
  • ingenol mebutate topical
  • momelotinib
  • trastuzumab/deruxtecan
  • trastuzumab/hyaluronidase
  • trastuzumab duocarmazine
  • lifileucel
  • umbralisib
  • eflornithine/sulindac
  • cytarabine/daunorubicin liposomal
  • doxorubicin liposomal
  • epcoritamab
  • lanadelumab  
  • esomeprazole/naproxen 
  • terbinafine topical
  • ravulizumab
  • clotrimazole topical
  • choline magnesium trisalicylate
  • tacrolimus ointment
  • mechlorethamine topical
  • donislecel
  • pozelimab (Pending FDA Approval)
  • rabies immune globulin, human (RIG)
  • melphalan flufenamide
  • sintilimab (Pending FDA Approval)
  • oportuzumab monatox (Pending FDA Approval)
  • sotorasib
  • irinotecan liposomal
  • sulfur topical
  • silver sulfadiazine
  • capsaicin transdermal
  • sutimlimab
  • tretinoin topical
  • acetaminophen rectal
  • menthol topical
  • naftifine
  • oatmeal, colloidal topical
  • oxiconazole
  • methylsalicylate/menthol topical
  • C1 inhibitor human
  • lifitegrast ophthalmic
  • prednisolone/sulfacetamide ophthalmic
  • mannitol inhalation
  • ofloxacin otic
  • petrolatum & mineral oil topical
  • clascoterone topical
  • gefapixant (Pending FDA Approval)
  • colesevelam
  • technetium Tc 99m succimer
  • nebivolol/valsartan
  • ciprofloxacin/fluocinolone acetonide, otic
  • finafloxacin otic
  • magnesium hydroxide/mineral oil
  • phenylephrine/mineral oil/petrolatum rectal
  • carbamide peroxide oral
  • atropine ophthalmic
  • sodium sulfacetamide/sulfur
  • sulfacetamide ophthalmic
  • lucinactant
  • benzonatate
  • besifloxacin ophthalmic
  • benzhydrocodone/acetaminophen
  • beractant
  • trimagnesium citrate anhydrous
  • vitamin b2
  • carbamide peroxide otic
  • mineral oil topical
  • ethyl alcohol intranasal
  • boric acid/alcohol otic
  • absorbable gelatin compressed sponge, USP
  • absorbable gelatin sponge, USP
  • vincristine liposomal
  • technetium Tc 99m albumin aggregated injection
  • metaproterenol
  • budesonide inhaled/formoterol/glycopyrrolate inhaled
  • epinephrine racemic
  • umeclidinium bromide/vilanterol inhaled
  • indacaterol, inhaled/glycopyrrolate inhaled
  • betaine  
  • laronidase 
  • estrogens esterified/methyltestosterone            
  • cerliponase alfa
  • ertugliflozin/sitagliptin
  • hawthorn
  • shepherd’s purse
  • thiamine
  • naphazoline/glycerin ophthalmic
  • oxymetazoline ophthalmic
  • dorzolamide
  • dexamethasone intraocular
  • dexamethasone/ciprofloxacin
  • dexamethasone ophthalmic
  • metipranolol ophthalmic
  • timolol ophthalmic
  • boron
  • fezolinetant
  • pegunigalsidase alfa-iwxj
  • biotin
  • pantothenic acid
  • silicon
  • sodium acid phosphate
  • hypochlorous acid topical
  • methenamine/sodium acid phosphate
  • aviptadil 
  • bremelanotide
  • glucagon intranasal
  • metformin and repaglinide
  • bai ji
  • pau d’arco
  • juzentaihoto
  • mistletoe
  • quercetin
  • rosemary
  • sheng di huang
  • chasteberry
  • maitake
  • grapefruit
  • lentinan
  • juniper
  • nettle
  • parsley
  • rose hips
  • tongkat ali
  • horny goat weed
  • damiana
  • yohimbe
  • insulin NPH
  • aprocitentan
  • noni Juice
  • sodium iodide I-131
  • green tea
  • sea cucumber
  • wheat germ extract
  • fenofibrate micronized 
  • rogisen
  • danshen
  • lutein
  • witch hazel
  • dextroamphetamine transdermal
  • amphetamine/dextroamphetamine
  • hoodia
  • kolanut
  • boswellia
  • opuntia ficus indica
  • lavender
  • nadh
  • tea tree oil
  • metformin/sitagliptin 
  • dapagliflozin/ metformin/saxagliptin  
  • antihemophilic factor recombinant
  • inclisiran
  • bempedoic acid/ezetimibe
  • volanesorsen  
  • omega 3 carboxylic acids
  • pericyazine
  • levomepromazine (methotrimeprazine)
  • betaxolol ophthalmic
  • respiratory syncytial virus vaccine, adjuvanted
  • phenylephrine hydrochloride and tropicamide ophthalmic
  • alirocumab
  • neomycin/polymyxin B/gramicidin ophthalmic
  • factor IX
  • gentamicin topical
  • ansofaxine (Pending FDA Approval)
  • zuranolone
  • factor IX, recombinant
  • factor IX complex
  • factor XIII A-subunit, recombinant
  • factor X, human
  • mesalamine rectal
  • etrasimod
  • anti-inhibitor coagulant complex
  • factor IX, recombinant/albumin fusion protein
  • fibrinogen, human
  • aminocaproic acid
  • metyrosine
  • nonoxynol-9 vaginal
  • progesterone intravaginal gel
  • ipecac syrup
  • botulinum antitoxin, heptavalent
  • pentetate calcium trisodium
  • crotalidae polyvalent immune FAB (ovine)
  • dehydrated alcohol injection 
  • gold sodium thiomalate (Discontinued)
  • lactic acid/citric acid/potassium bitartrate vaginal
  • von Willebrand factor, recombinant
  • luspatercept
  • digoxin immune FAB (Antidote)
  • crotalidae immune FAB (equine)
  • magnesium (Antidote)
  • pyridoxine (Antidote)
  • edetate calcium disodium
  • albumin IV
  • nitroglycerin sublingual
  • obiltoxaximab
  • anthrax immune globulin
  • nitroglycerin topical
  • dextrose
  • nesiritide
  • estradiol vaginal
  • bazedoxifene/conjugated estrogens
  • botulism immune globulin iv
  • amoxicillin/omeprazole/rifabutin
  • synthetic human angiotensin II
  • nitroglycerin IV
  • nitroglycerin translingual
  • nitroprusside sodium
  • tetrahydrozoline/zinc sulfate/hypromellose ophthalmic
  • sodium citrate/citric acid
  • pemetrexate
  • methicillin
  • plasminogen 
  • acai
  • american ginseng
  • cordyceps
  • tramadol/acetaminophen
  • belladonna alkaloids/phenobarbital
  • erythromycin topical/benzoyl peroxide
  • glucosamine sulfate
  • panax ginseng (suppl/herb)
  • tolnaftate
  • sulopenem etzadroxil/probenecid
  • sulfur hexafluoride
  • sotrovimab
  • arbaclofen
  • rifampin/isoniazid
  • clindamycin /tretinoin topical
  • benzoyl peroxide/clindamycin topical
  • apremilast
  • antivenins, centuroides (scorpion)
  • bamlanivimab and etesevimab
  • vilobelimab
  • gadobenate
  • pentosan polysulfate sodium
  • methylsalicylate/menthol/camphor topical
  • antivenin, black widow spider
  • benzoyl peroxide and hydrocortisone
  • clindamycin topical
  • isometheptene, dichloralphenazone and acetaminophen
  • acetaminophen and phenyltoloxamine
  • erythromycin topical
  • erythromycin ophthalmic
  • alpha hydroxy acids, topical
  • buprenorphine transdermal
  • butalbital/acetaminophen/caffeine
  • buprenorphine/samidorphan
  • buprenorphine subdermal implant
  • celecoxib/tramadol
  • drospirenone/ethinyl estradiol
  • resorcinol/sulfur
  • eflornithine
  • rifampin/isoniazid/pyrazinamide
  • tofersen
  • devil’s claw
  • ticarcillin/clavulanate
  • atropine/pralidoxime
  • aprepitant
  • suramin
  • phenelzine 
  • artichoke
  • american dogwood
  • attapulgite
  • atlantic cedar
  • axalimogene filolisbac
  • sodium thiosulfate & sodium nitrite
  • ataluren
  • omidubicel-onlv
  • capsicum
  • ginger
  • cryoprecipitate
  • bictegravir/emtricitabine/tenofovir DF
  • emtricitabine/tenofovir DF
  • fo-ti
  • siberian ginseng
  • granulocytes
  • zinc substituted heme C
  • zinc trihydroxide
  • ashwagandha 
  • cat’s claw
  • glandular products
  • SAMe
  • shark cartilage
  • altovis
  • feverfew
  • horse chestnut
  • magnesium aspartate
  • octacosanol
  • pleurisy root
  • star anise
  • butterbur
  • elderberry
  • licorice (Suppl/herb)
  • aconite
  • pentetate zinc trisodium
  • menthol topical/zinc oxide topical
  • corn-starch/kaolin/zinc oxide topical
  • 5-htp
  • butcher’s broom
  • articulin
  • bearberry
  • goldenrod
  • progesterone, natural
  • black cohosh
  • wild yam
  • cranberry
  • dong quai
  • phytoestrogens
  • norethindrone
  • false Unicorn Root
  • raspberry Leaf
  • asafoetida
  • turmeric
  • dehydroepiandrosterone (DHEA)
  • hyaluronan
  • aliskiren/amlodipine
  • octreotide (Antidote)
  • tranexamic acid injection
  • duocal
  • neocate infant formula
  • pediatric Eo28
  • aloe
  • red clover
  • propolis
  • androstenedione
  • heartsease
  • comfrey
  • bilberry
  • chamomile
  • eyebright
  • calendula
  • sage
  • yucca
  • polypody
  • odevixibat
  • vinpocetine
  • olanzapine/samidorphan
  • creatine
  • yerba mate
  • spesolimab
  • azficel-T
  • tiludronate
  • estetrol and drospirenone
  • pseudoephedrine/fexofenadine
  • lincomycin
  • neomycin oral
  • fluocinolone acetonide, otic
  • tretinoin/ hydroquinone/ fluocinolone
  • halobetasol topical
  • hydrocortisone/​iodoquinol
  • penicillin G procaine /penicillin G benzathine
  • hydrocortisone probutate topical
  • colistin/neomycin/hydrocortisone/thonzonium otic
  • ebola zaire vaccine
  • hepatitis a/​b vaccine
  • vibegron
  • lindane
  • nystatin topical
  • respiratory syncytial virus (RSV) vaccine
  • chikungunya vaccine
  • tenecteplase
  • reteplase
  • anthrax vaccine adsorbed, adjuvanted
  • meningococcal ABCWY pentavalent vaccine
  • eculizumab
  • cholestyramine
  • tinzaparin
  • taurolidine/​citrate/​heparin
  • protein C concentrate
  • antithrombin alfa
  • antithrombin III
  • multivitamins, vision
  • ibuprofen/​chlorpheniramine/​pseudoephedrine
  • acetaminophen/ibuprofen
  • ibuprofen/pseudoephedrine
  • paclitaxel protein-bound
  • acetic acid vaginal
  • acetic acid otic
  • hydrocodone/ ibuprofen
  • methyl salicylate / isopropanol/ citronellyl acetate/ citric acid
  • ibuprofen and phenylephrine
  • acetylcysteine (Antidote)
  • iron/​folic acid/​vitamin/​mineral
  • iobenguane I-131
  • dolutegravir/rilpivirine
  • chlorhexidine topical
  • chlorhexidine oral
  • thyroid desiccated
  • proparacaine ophthalmic
  • podophyllum resin
  • phendimetrazine
  • phenoxybenzamine
  • polidocanol
  • phentermine and topiramate
  • piflufolastat F18
  • piperacillin/tazobactam
  • prednisolone and gentamicin ophthalmic
  • promethazine and codeine
  • poractant alfa
  • protamine sulfate
  • aflibercept intravitreal
  • prednicarbate
  • promethazine/dextromethorphan
  • codeine, phenylephrine, and promethazine
  • potassium phosphate
  • glatiramer acetate
  • gentamicin (Ophthalmic)
  • leniolisib
  • rezafungin
  • fluorometholone
  • dalfampridine
  • hydrocortisone topical 
  • empagliflozin and linagliptin
  • triamcinolone topical
  • minocycline topical
  • minocycline dental
  • ketotifen ophthalmic
  • darunavir and cobicistat
  • lidocaine topical
  • neomycin/polymyxin B/bacitracin/lidocaine (OTC)
  • lidocaine/ hydrocortisone
  • lidocaine anesthetic
  • lidocaine ophthalmic
  • lidocaine/tetracaine
  • desonide
  • dabigatran
  • fexofenadine
  • fluoride
  • decitabine and cedazuridine
  • dasiglucagon
  • hydroxypropyl cellulose ophthalmic
  • epoetin alfa
  • ibritumomab tiuxetan
  • trimethobenzamide
  • dexamethasone/ tobramycin
  • tafasitamab
  • valacyclovir
  • mebendazole
  • levoleucovorin
  • flaxseed
  • germanium
  • glutathione
  • lycopene
  • pygeum
  • horseradish
  • ziv-aflibercept
  • micafungin
  • trofinetide
  • taliglucerase alfa
  • tildrakizumab
  • sulopenem (Pending FDA Approval)
  • thyrotropin alfa
  • birch
  • thrombin, topical
  • tivozanib
  • tafluprost
  • methohexital
  • urea and hydrocortisone
  • unoprostone ophthalmic
  • trihexyphenidyl
  • ezetimibe
  • evolocumab
  • trifluridine and tipiracil
  • methenamine
  • misoprostol
  • miltefosine
  • rimantadine
  • maralixibat
  • coenzyme Q10
  • chlorella
  • garlic
  • forskolin
  • zavegepant
  • menotropins
  • margetuximab
  • meprobamate
  • melarsoprol
  • evening primrose oil
  • lemongrass
  • molindone
  • fenugreek
  • phytosterols
  • red yeast rice
  • uridine triacetate
  • tropicamide
  • incobotulinumtoxinA
  • Grape Seed Extract
  • carbachol ophthalmic
  • cosyntropin
  • cyclopentolate and phenylephrine
  • carteolol ophthalmic
  • pentazocine/naloxone
  • pentazocine/acetaminophen
  • casimersen
  • carisoprodol, aspirin, and codeine
  • carisoprodol
  • carboprost tromethamine
  • flurandrenolide
  • brinzolamide/brimonidine
  • betamethasone topical
  • omaveloxolone
  • bardoxolone
  • allogeneic processed thymus tissue
  • fluocinolone topical
  • tacrolimus topical
  • ruxolitinib topical
  • pimecrolimus topical
  • sofosbuvir, velpatasvir and voxilaprevir
  • sofosbuvir/velpatasvir
  • mitotane
  • elbasvir/​grazoprevir
  • wheat dextrin
  • vanadium
  • iron/folic acid/vitamin/mineral
  • molybdenum
  • sparsentan
  • velmanase alfa-tycv
  • pegcetacoplan
  • ferrous sulfate
  • cyclosporine ophthalmic
  • ferric pyrophosphate
  • ammonium lactate
  • etelcalcetide
  • iodoquinol
  • sucroferric oxyhydroxide
  • doxercalciferol
  • terconazole vaginal
  • cortisone
  • pyronaridine
  • tetrahydrozoline, ophthalmic
  • tenapanor
  • tesamorelin
  • benazepril/hydrochlorothiazide
  • nadolol and bendroflumethiazide
  • spironolactone and hydrochlorothiazide
  • COVID-19 Vaccine, mRNA
  • atosiban
  • bisoprolol and hydrochlorothiazide
  • ephedrine/guaifenesin
  • clonidine/chlorthalidone
  • captopril/hydrochlorothiazide
  • amlodipine/valsartan/hydrochlorothiazide
  • hydrochlorothiazide and irbesartan
  • candesartan/hydrochlorothiazide
  • ciclesonide intranasal
  • cromolyn sodium ophthalmic
  • methyldopa/hydrochlorothiazide
  • valsartan/hydrochlorothiazide
  • hydrochlorothiazide and triamterene
  • moexipril/hydrochlorothiazide
  • mometasone/intranasal
  • ofloxacin ophthalmic
  • cysteamine
  • metoprolol/hydrochlorothiazide
  • amlodipine/olmesartan
  • eprosartan/hydrochlorothiazide
  • amlodipine/telmisartan
  • hydrochlorothiazide/aliskiren
  • betamethasone/clotrimazole
  • telmisartan/hydrochlorothiazide
  • benazepril/amlodipine
  • bezlotoxumab
  • propranolol/hydrochlorothiazide
  • bupropion/naltrexone
  • burosumab
  • acetylcholine chloride intraocular solution
  • bupivacaine and meloxicam
  • budesonide and formoterol (inhalation)
  • valerian
  • entacapone/levodopa/carbidopa
  • carbidopa/levodopa
  • calaspargase pegol
  • cabotegravir
  • cefixime
  • calfactant
  • brinzolamide
  • daprodustat
  • brimonidine and timolol
  • brodalumab
  • buprenorphine and naloxone
  • hydrocortisone acetic acid otic
  • butorphanol
  • butoconazole
  • adapalene and benzoyl peroxide
  • acrivastine and pseudoephedrine
  • neomycin/polymyxin B/bacitracin topical
  • midodrine
  • baloxavir marboxil
  • bacitracin, neomycin, polymyxin B, and hydrocortisone topical
  • avatrombopag
  • glucagon
  • atenolol/chlorthalidone
  • adefovir
  • activated charcoal
  • avalglucosidase alfa
  • aclidinium and formoterol
  • iclaprim (Pending FDA Approval)
  • ampicillin/sulbactam
  • quinupristin/dalfopristin
  • lamivudine/zidovudine/abacavir
  • acetaminophen and caffeine
  • acetaminophen/pamabrom
  • abacavir and lamivudine
  • anifrolumab
  • elacestrant
  • anidulafungin
  • acetohydroxamic acid
  • alogliptin/pioglitazone
  • anthralin
  • pirtobrutinib
  • gabapentin
  • galsulfase
  • gadoterate meglumine
  • ferric gluconate
  • ferric derisomaltose
  • ethanolamine oleate
  • eteplirsen
  • vasopressin
  • desmopressin
  • meropenem/vaborbactam
  • ecallantide
  • econazole topical
  • dornase alfa
  • aspirin/dipyridamole
  • dipyridamole
  • difenoxin and atropine
  • diflorasone
  • difluprednate ophthalmic
  • eptinezumab
  • diethylpropion
  • dexchlorpheniramine
  • dexmethylphenidate
  • serdexmethylphenidate/​dexmethylphenidate
  • bexagliflozin
  • galcanezumab
  • fremanezumab
  • tapinarof topical
  • darifenacin
  • dalbavancin
  • darbepoetin alfa
  • azilsartan
  • colestipol
  • corticorelin
  • crotamiton
  • crofelemer
  • allogeneic cultured keratinocytes/fibroblasts in bovine collagen
  • tapentadol
  • cyclopentolate
  • polymyxin B/bacitracin topical
  • tavaborole
  • tagraxofusp
  • crisaborole
  • crizanlizumab
  • satralizumab
  • spinosad
  • sacubitril/valsartan
  • sargramostim
  • sebelipase alfa
  • regadenoson
  • ribociclib/letrozole
  • ragweed allergen extract
  • radium-223 dichloride
  • secnidazole
  • setmelanotide
  • polycarbophil
  • plecanatide
  • sacituzumab govitecan
  • pertuzumab
  • pertuzumab/trastuzumab/hyaluronidase
  • pamidronate
  • halcinonide
  • glecaprevir/​pibrentasvir
  • glucarpidase
  • golodirsen
  • dextrose (antidote)
  • hexaminolevulinate
  • iohexol
  • ferric citrate
  • elapegademase
  • emicizumab
  • erenumab
  • danaparoid
  • dantrolene
  • eflapegrastim
  • edaravone
  • amcinonide
  • carglumic acid
  • alcaftadine ophthalmic
  • agalsidase beta
  • afamelanotide
  • fosdenopterin
  • lidocaine and chlorhexidine
  • levorphanol
  • calcifediol
  • factor VIIa, recombinant
  • triheptanoin
  • peanut oral allergen powder
  • teprotumumab
  • poly-L-lactic acid/carboxymethylcellulose/mannitol
  • xenon Xe 129 hyperpolarized
  • ublituximab
  • anacaulase
  • glatiramer
  • peginterferon beta-1a
  • interferon beta-1a
  • onabotulinumtoxinA
  • cycloserine
  • ethionamide
  • cabotegravir and rilpivirine
  • vericiguat
  • omidenepag isopropyl
  • azelastine/fluticasone intranasal
  • benzyl peroxide
  • vutrisiran
  • brimonidine
  • testosterone topical
  • lenacapavir
  • tebentafusp
  • mosunetuzumab
  • faricimab
  • ganirelix
  • nadofaragene firadenovec
  • ozenoxacin
  • guaifenesin
  • adagrasib
  • guselkumab
  • adalimumab-aacf
  • nonoxynol-9
  • nifurtimox
  • nusinersen
  • nitazoxanide
  • mavacamten
  • calcipotriene
  • bimatoprost
  • obinutuzumab
  • amifostine
  • oxycodone/​aspirin
  • oxycodone/ibuprofen
  • oteseconazole
  • oxychlorosene
  • porfimer
  • pramoxine /hydrocortisone topical
  • podofilox
  • quinapril/hydrochlorothiazide
  • acetaminophen/pamabrom/pyrilamine
  • levobunolol
  • paregoric
  • idursulfase
  • lesinurad and allopurinol
  • latanoprost/​netarsudil ophthalmic
  • lactase enzyme
  • bioadherent oral
  • latanoprost and timolol
  • latanoprostene bunod
  • ledipasvir/sofosbuvir
  • imipenem/cilastatin/relebactam
  • imipenem/cilastatin
  • hemin
  • deucravacitinib
  • house dust mite allergen extract
  • halobetasol topical/tazarotene
  • remimazolam
  • somatropin
  • remifentanil
  • ethotoin
  • etidronate
  • empagliflozin, linagliptin, and metformin
  • elvitegravir/cobicistat/emtricitabine/tenofovir AF
  • empagliflozin/metformin
  • evinacumab
  • finasteride and tadalafil
  • flortaucipir (18F)
  • proparacaine/ fluorescein ophthalmic
  • fluorescein/benoxinate ophthalmic
  • fluphenazine
  • alogliptin/​metformin
  • alogliptin/pioglitazone
  • alitretinoin topical
  • dextrose/ sodium citrate/fructose
  • dasabuvir
  • ombitasvir​/paritaprevir/​ritonavir
  • hydrocodone/​chlorpheniramine/​pseudoephedrine
  • hydroxyamphetamine/​tropicamide
  • acamprosate
  • gadobutrol
  • teclistamab
  • tremelimumab
  • futibatinib
  • etranacogene dezaparvovec
  • olutasidenib
  • naproxen and diphenhydramine
  • naratriptan
  • gadopiclenol
  • gadoxetate
  • gadoversetamide
  • naphazoline/pheniramine
  • naphazoline
  • nalbuphine
  • vosoritide
  • vitamin K1 (phytonadione)
  • moxidectin
  • basiliximab
  • fecal microbiota, live-jslm
  • ibuprofen/famotidine
  • famotidine
  • raxibacumab
  • omalizumab
  • measles, mumps, rubella, and varicella vaccine, live (Rx)
  • senna/docusate
  • dinoprostone
  • measles mumps and rubella vaccine, live
  • immune globulin IM (IGIM)
  • dyclonine
  • doravirine, lamivudine, and tenofovir disoproxil fumarate
  • elexacaftor/tezacaftor/ivacaftor
  • ivacaftor/tezacaftor
  • treosulfan
  • tranexamic acid
  • norethindrone acetate/​estradiol/​elagolix
  • artesunate
  • trientine
  • trifarotene
  • ziconotide
  • vonoprazan/amoxicillin/clarithromycin
  • pyrithione zinc
  • zinc oxide topical
  • naphazoline/​zinc sulfate/​glycerin ophthalmic
  • voretigene neparvovec
  • nirmatrelvir/ritonavir
  • bebetelovimab
  • sodium chloride
  • relugolix/​estradiol/​norethindrone
  • defibrotide
  • prothionamide
  • liraglutide
  • etilfrine
  • alpha-lipoic acid
  • ramosetron
  • olodaterol/tritropium
  • cimetropium
  • umeclidinium
  • itopride
  • secretin
  • naftopidil
  • trimeprazine
  • benperidol
  • chlormethiazole
  • multivitamins
  • secukinumab
  • glycopyrrolate inhaled and formoterol
  • amitriptyline and chlordiazepoxide
  • tirzepatide
  • relugolix/estradiol/norethindrone
  • mupirocin
  • alvimopan
  • chlordiazepoxide
  • insulin regular human
  • insulin aspart protamine/​insulin aspart
  • insulin isophane human/​insulin regular human
  • insulin degludec/insulin aspart
  • teplizumab
  • chlordiazepoxide/clidinium
  • aspirin, sodium bicarbonate, and citric acid
  • aluminum hydroxide, magnesium hydroxide, and simethicone
  • glycopyrrolate inhaled
  • olodaterol/tiotropium
  • umeclidinium bromide
  • timolol/dorzolamide
  • travoprost ophthalmic
  • loxapine
  • eptifibatide
  • hydrocodone/acetaminophen
  • omega 3 fatty acids
  • trandolapril/​verapamil
  • abciximab
  • artificial saliva
  • diphtheria, hepatitis B, pertussis (acellular), polio, and tetanus vaccine
  • diphtheria, haemophilus B, pertussis, polio, tetanus vaccine
  • haemophilus influenzae type b vaccine/hepatitis b vaccine
  • butalbital/aspirin/caffeine 
  • colchicine/probenecid
  • atovaquone and proguanil
  • ursodiol
  • chenodiol
  • casirivimab/imdevimab
  • tixagevimab/cilgavimab
  • molnupiravir
  • bebtelovimab
  • calcium, magnesium, potassium and sodium oxybate
  • sodium oxybate
  • diphtheria, polio, pertussis acellular, tetanus vaccine
  • pseudoephedrine loratadine
  • sodium chloride nasal
  • hydroxychloroquine sulfate
  • atorvastatin and ezetimibe
  • teriparatide
  • alendronate and cholecalciferol
  • alprostadil (IV)
  • romosozumab
  • risedronate
  • alendronate
  • glyburide/metformin
  • clorazepate
  • rosuvastatin/​ezetimibe
  • paclitaxel/encequidar
  • valsartan/amlodipine
  • enalapril/hydrochlorothiazide
  • enalapril and felodipine
  • amiloride/hydrochlorothiazide
  • triamterene/hydrochlorothiazide
  • lisinopril/hydrochlorothiazide
  • tegaserod
  • rhein
  • ritanserin
  • sulfaphenazole
  • sulconazole
  • taurursodiol
  • bromeperidol
  • carbapenems
  • fotemustine
  • difelikefalin
  • bromopride
  • alizapride
  • olopatadine
  • oxomemazine
  • paraldehyde
  • oxcarbazepine
  • kratom
  • elexacaftor
  • oritavancin
  • miocamycin
  • curcumin sulfate
  • seproxetine
  • clotrimazole
  • remacemide
  • piperine
  • ditiocarb
  • danoprevir
  • oxetacaine
  • topiroxostat
  • indisulam
  • tofisopam
  • noscapine
  • thiopental
  • tioconazole
  • nicotinamide
  • rutin
  • mequitazine
  • somatostatin
  • vapreotide
  • econazole
  • saracatinib
  • lestaurtinib
  • efonidipine
  • zimelidine
  • indalpine
  • desvenlafaxine
  • benidipine
  • dapoxetine
  • tesmilifene
  • pergolide
  • sitaxentan
  • resveratrol
  • bifonazole
  • tildipirosin
  • solithromycin
  • selamectin
  • imiquimod topical
  • fluorouracil topical
  • peginterferon alfa-2b
  • interferon alfa-2b
  • alteplase
  • tanshinone I
  • rosmarinic acid
  • caryophyllene
  • ursolic acid
  • cepharanthine
  • veliflapon
  • mirikizumab
  • cp-96345
  • famprofazone
  • peoniflorin
  • fepradinol
  • licofelone
  • polmacoxib
  • ebselen
  • taxifolin
  • betulinic acid
  • flurbiprofen axetil
  • talniflumate
  • morniflumate
  • nitroaspirin
  • firocoxib
  • ns-398
  • cimicoxib
  • robenacoxib
  • sc-236
  • imidazole salicylate
  • trolamine salicylate
  • pirprofen
  • benorilate
  • ethenzamide
  • mofebutazone
  • proquazone
  • carbaspirin calcium
  • guacetisal
  • proglumetacin
  • propyphenazone
  • pranoprofen
  • bendazac
  • tenidap
  • lonazolac
  • nifenazone
  • flunoxaprofen
  • difenpiramide
  • feprazone
  • bufexamac
  • alminoprofen
  • suxibuzone
  • fentiazac
  • tinoridine
  • tepoxalin
  • indobufen
  • flunixin
  • propacetamol
  • clonixin
  • droxicam
  • epirizole
  • etofenamate
  • ibuproxam
  • indoprofen
  • kebuzone
  • felbinac
  • zaltoprofen
  • azapropazone
  • zomepirac
  • niflumic acid
  • magnesium salicylate
  • suprofen
  • nepafenac
  • bromfenac
  • ciprofloxacin and hydrocortisone (otic) (Rx)
  • hydrocortisone/neomycin/polymyxin otic (Rx)
  • vigabatrine
  • valproate sodium injection
  • tezepelumab (Rx)
  • triamcinolone acetonide/nystatin
  • triamcinolone suprachoroidal (Rx)
  • triamcinolone, intranasal
  • ciclesonide inhaled
  • diosmin
  • tirbanibulin
  • padeliporfin
  • roxadustat
  • aminosalicylic acid
  • rasburicase
  • tetracaine
  • articaine
  • ropivacaine
  • nitrous oxide
  • sulfapyridine
  • sulfanilamide
  • mafenide
  • isometheptene
  • amyl nitrite
  • antipyrine
  • isosorbide dinitrate
  • prilocaine
  • nitroglycerin
  • tobacco
  • batefenterol
  • hexoprenaline
  • pf-00610355
  • racepinephrine
  • protokylol
  • doxofylline
  • phenylpropanolamine
  • isoetharine
  • ephedra sinica root
  • dipivefrin
  • arbutamine
  • norepinephrine
  • fenoterol
  • clenbuterol
  • pirbuterol
  • epinephrine
  • ritodrine
  • procaterol
  • orciprenaline
  • bitolterol
  • abediterol
  • fluticasone furoate, umeclidinium and vilanterol
  • fluticasone furoate and vilanterol
  • mometasone and formoterol
  • pramoxine topical (OTC)
  • menthol/pramoxine (topical)
  • tetrastarch
  • plasma protein fraction
  • hetastarch
  • rokitamycin
  • ridaforolimus
  • oleandomycin
  • patupilone
  • mitemcinal
  • midecamycin
  • mirvetuximab soravtansine
  • lorvotuzumab mertansine
  • kitasamycin
  • flurithromycin
  • eprinomectin
  • epofolate
  • epothilone D
  • coltuximab ravtansine
  • dirithromycin
  • doramectin
  • cethromycin
  • carbomycin
  • paramethasone
  • dexamethasone isonicotinate
  • quinupristin
  • sarilumab
  • dalfopristin
  • curcumin
  • luliconazole
  • procaine
  • chloroprocaine
  • phencyclidine
  • tenocyclidine
  • profenamine
  • halothane
  • lfenprodil
  • calcium levulinate
  • agmatine
  • calcium pangamate
  • calcium glubionate
  • edodekin alfa
  • beloranib
  • aflibercept
  • endostar
  • volociximab
  • roquinimex
  • anecortave acetate
  • squalamine
  • brolucizumab
  • trebananib
  • semaxanib
  • endostatin
  • halofuginone
  • resveratol
  • ranibizumab
  • fumagilin
  • bevacizumab
  • hyperforin
  • aminohippuric acid
  • opicapone
  • pafolacianine
  • bempedoic acid
  • belantamab mafodotin
  • prasterone
  • glecaprevir
  • levomenol
  • parachlorophenol
  • gadoxetic acid
  • cholecystokinin
  • caspofungin
  • ouabain
  • rifampicin
  • taurocholic acid
  • methylphosphinic acid
  • revefenacin
  • isoprenaline
  • posiphen
  • acotiamide
  • triflupromazine
  • pegvisomant
  • pipecuronium
  • regramostim
  • phenserine
  • diethylcarbamazine
  • cinchocaine
  • pancuronium
  • bambuterol
  • hexafluronium
  • aprotinin
  • tyrothricin
  • decamethonium
  • ipidacrine
  • tubocurarine
  • paraoxon
  • ginkgo biloba
  • methanesulfonyl fluoride
  • dichlorvos
  • fenthion
  • metrifonate
  • coumaphos
  • huperzine A
  • distigmine
  • neostigmine
  • isoflurophate
  • tasosartan
  • fimasartan
  • methylthioninium
  • minaprine
  • gallamine triethiodide
  • ambenonium
  • abiraterone
  • mibefradil
  • hydrocortisone (systemic)
  • cetirizine (systemic)
  • Talimogene Laherparepvec
  • Diacerein
  • magnesium glucoheptonate
  • acyclovir and hydrocortisone
  • acyclovir (ophthalmic)
  • acyclovir (topical)
  • docosanol cream
  • camphor and phenol
  • dolutegravir, abacavir, and lamivudine
  • peramivir
  • lisdexamfetamine
  • ergoloid mesylates
  • memantine/donepezil
  • tranylcypromine
  • isocarboxazid
  • methenamine/sodium salicylate/benzoic acid
  • mometasone topical (Rx)
  • Esketamine intranasal
  • Oracit
  • Shohls Solution
  • sodium lactate
  • sodium citrate
  • lecanemab
  • donepezil (Rx)
  • donepezil transdermal
  • sodium thiosulfate
  • ciclopirox
  • undecylenic acid
  • butenafine
  • calcium and vitamin D
  • zoledronic acid
  • calcitonin salmon
  • pizotifen
  • indoramin
  • salicylic acid acne
  • minoxidil topical
  • adapalene
  • orlistat
  • COVID-19 subunit vaccine
  • amoxicillin /vonoprazan
  • levamlodipine (Rx)
  • Omeprazole, amoxicillin, and clarithromycin
  • simvastatin/ezetimibe
  • amlodipine/atorvastatin
  • amoxicillin and clavulanate potassium
  • lansoprazole, amoxicillin, and clarithromycin
  • noradrenaline
  • carbaryl
  • botulinum toxin
  • atropine
  • artemether/lumefantrine
  • ergonovine
  • bunazosin (Not available in the United States)
  • ibalizumab
  • dolutegravir
  • hydrocodone/pseudoephedrine
  • cetirizine/pseudoephedrine
  • acetaminophen/dextromethorphan/pseudoephedrine/guaifenesin
  • acetaminophen IV/ibuprofen IV (Pending FDA Approval)
mibefradil + 

mibefradil

may enhance the QTc-prolonging effect of QT-prolonging agents

ibandronate

may enhance the QTc-prolonging effect of QT-prolonging agents

trazodone

may enhance the QTc-prolonging effect of QT-prolonging agents

isradipine

may enhance the QTc-prolonging effect of QT-prolonging agents

treprostinil

may enhance the QTc-prolonging effect of QT-prolonging agents

labetalol 

may increase the hypotensive effect of alpha1-blockers

epcoritamab

may enhance the serum concentration of each other when combined

adagrasib

may enhance the serum concentration of each other when combined

imiquimod topical

may enhance the serum concentration of each other when combined

fluorouracil topical

may enhance the serum concentration of each other when combined

peginterferon alfa-2b

may enhance the serum concentration of each other when combined

medroxyprogesterone

CYP3A4 Inhibitors: they may diminish the serum concentration of hormonal contraceptives

megestrol

CYP3A4 Inhibitors: they may diminish the serum concentration of hormonal contraceptives

levonorgestrel

CYP3A4 Inhibitors: they may diminish the serum concentration of hormonal contraceptives

lynestrenol

CYP3A4 Inhibitors: they may diminish the serum concentration of hormonal contraceptives

abiraterone

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

lanreotide

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

cyproterone

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

triptorelin

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

darolutamide

CYP3A Inhibitors: they may diminish the serum concentration of hormonal agents

delamanid

QT-prolonging Strong may enhance the QTc-prolonging effect of delamanid

dasatinib

dasatinib may enhance the QTc-prolonging effect of QT-prolonging

l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine

may decrease the serum concentration of Quinolones

ceritinib

bradycardia-Causing Agents may enhance the bradycardic effect of Ceritinib

ponesimod

bradycardia-Causing Agents may enhance the bradycardic effect of ponesimod

fluorouracil

may enhance the QTc-prolonging effect of Fluorouracil Products

gilteritinib

gilteritinib may enhance the QTc-prolonging effect of QT-prolonging Agents

colchicine 

may increase the serum concentration of colchicine

domperidone 

may enhance the Qtc prolonging effect

ivacaftor/tezacaftor 

may increase the levels of serum concentration of ivacaftor/tezacaftor

deflazacort 

may enhance the serum concentrations of active metabolites

abiraterone

may enhance the QTc-prolonging effect of QT-prolonging agents

mibefradil

may enhance the QTc-prolonging effect of QT-prolonging agents

citalopram

may enhance the QTc-prolonging effect of QT-prolonging agents

efavirenz

may enhance the QTc-prolonging effect of QT-prolonging agents

isoniazid

may enhance the QTc-prolonging effect of QT-prolonging agents

avapritinib 

may enhance the serum concentration

risperidone 

may increase the serum concentration

risperidone 

may increase the QTc prolonging effect

gemifloxacin 

may increase the QTc prolonging effect

amifostine 

may increase the hypotensive effect of anti-hypertensive agents

obinutuzumab 

may increase the hypotensive effect of anti-hypertensive agents

ceritinib 

may increase the bradycardic effect of bradycardia-causing agents

tetrabenazine 

may enhance serum concentrations when combined with tetrabenazine

adagrasib 

may increase the level of serum concentration of adagrasib

fenfluramine 

may enhance the serum concentration when combined with fenfluramine

fenfluramine 

may enhance the serum concentration when combined with fenfluramine

fexinidazole 

may diminish the serum concentration when combined with CYP2D6 substrates

amisulpride 

may have an increased QTc-prolonging effect when combined with amisulpride (oral)

rimantadine 

may decrease the therapeutic effect of each other when combined

tizanidine 

may enhance the serum concentration

ibutilide 

may increase the QTc prolonging effect of QT-prolonging Class III Antiarrhythmics

ibutilide 

may increase the QTc prolonging effect of QT-prolonging agents

ibutilide 

may increase the QTc prolonging effect of QT-prolonging Class III Antiarrhythmics

fingolimod 

may have an increased bradycardic effect when combined with fingolimod

ponesimod 

may have an increased bradycardic effect when combined with ponesimod

siponimod 

may have an increased bradycardic effect when combined with siponimod

rasagiline 

may increase the serum concentration of Rasagiline

amiodarone 

may have an increased QTc-prolonging effect when combined with amiodarone

arsenic trioxide 

may have an increased QTc-prolonging effect when combined with arsenic trioxide

astemizole 

may have an increased QTc-prolonging effect when combined with astemizole

bedaquiline 

may have an increased QTc-prolonging effect when combined with bedaquiline

chloroquine 

may have an increased QTc-prolonging effect when combined with chloroquine

chlorpromazine 

may have an increased QTc-prolonging effect when combined with chlorpromazine

cisapride 

may have an increased QTc-prolonging effect when combined with cisapride

clofazimine 

may have an increased QTc-prolonging effect when combined with clofazimine

clomipramine 

may have an increased QTc-prolonging effect when combined with QT-prolonging agents

clozapine 

may have an increased QTc-prolonging effect when combined with clozapine

dabrafenib 

may have an increased QTc-prolonging effect when combined with QT-prolonging agents

dasatinib 

may have an increased QTc-prolonging effect when combined with dasatinib

delamanid 

may have an increased QTc-prolonging effect when combined with delamanid

doxepin 

may have an increased QTc-prolonging effect when combined with doxepin-containing products

sevoflurane 

may increase the QTc-prolonging effect of QT-prolonging Agents

ceritinib 

may have an increased bradycardic effect when combined with ceritinib

fingolimod 

may have an increased bradycardic effect when combined with fingolimod

ponesimod 

may have an increased bradycardic effect when combined with ponesimod

siponimod 

may have an increased bradycardic effect when combined with siponimod

theophylline 

may enhance the concentration of serum when combined with theophylline derivatives

voxelotor 

may diminish the serum concentration of Voxelotor

thioridazine 

may enhance the concentration of serum when combined with thioridazine

lonafarnib 

lonafarnib: they may enhance the serum concentration of CYP3A4 Inhibitors

pirfenidone 

pirfenidone: they may enhance the serum concentration of CYP1A2 Inhibitors

pomalidomide 

pomalidomide: they may enhance the serum concentration of CYP1A2 Inhibitors

propranolol 

propranolol: they may enhance the serum concentration of CYP1A2 Inhibitors

sirolimus 

sirolimus: they may enhance the serum concentration of CYP3A4 Inhibitors

budesonide inhaled 

budesonide: they may enhance the serum concentration of CYP3A4 Inhibitors

saquinavir 

may increase the QTc-prolonging effect of each other when combined

chloroquine phosphate 

May enhance the QTc-prolonging effect of each other when combined

dronedarone 

dronedarone: they may increase the QTc-prolonging effect of QTc-prolonging miscellaneous agents

encorafenib 

encorafenib: they may increase the QTc-prolonging effect of QTc-prolonging agents

escitalopram 

escitalopram: they may increase the QTc-prolonging effect of QTc-prolonging Agents

etelcalcetide 

etelcalcetide: they may increase the QTc-prolonging effect of QTc-prolonging agents

flecainide 

flecainide: they may increase the QTc-prolonging effect of QTc-prolonging Agents

fluconazole 

fluconazole: they may increase the QTc-prolonging effect of QTc-prolonging agents

gilteritinib 

gilteritinib: they may increase the QTc-prolonging effect of QTc-prolonging agents

halofantrine 

halofantrine: they may increase the QTc-prolonging effect of QTc-prolonging Agents

imipramine 

imipramine: they may increase the QTc-prolonging effect of QTc-prolonging agents

inotuzumab 

inotuzumab: they may enhance the QTc-prolonging effect of QTc-prolonging agents

pentobarbital

may increase the hypotensive effect of anti-hypertensive agents

lofexidine 

lofexidine: they may increase the QTc-prolonging effect of QTc-prolonging Agents

methadone 

methadone: they may increase the QTc-prolonging effect of QTc -prolonging agents

midostaurin 

midostaurin: they may increase the QTc-prolonging effect of QTc-prolonging Agents

olanzapine 

olanzapine: they may enhance the QTc-prolonging effect of QTc-prolonging Agents

osimertinib 

osimertinib: they may increase the QTc-prolonging effect of QTc-prolonging Agents

propafenone 

propafenone: they may increase the QTc-prolonging effect of QTc-prolonging Agents

propofol 

propofol: they may increase the QTc-prolonging effect of QTc-prolonging Agents

sunitinib 

sunitinib: they may increase the QTc-prolonging effect of QTc-prolonging Agents

toremifene 

toremifene: they may increase the QTc-prolonging effect of QTc-prolonging Agents

vemurafenib 

vemurafenib: they may increase the QTc-prolonging effect of QTc-prolonging Agents

ripretinib 

ripretinib: they may diminish the serum concentration of CYP3A4 Inducers

fluspirilene

may increase the QTc-prolonging effect of each other when combined

ziprasidone

may increase the QTc-prolonging effect of each other when combined

ketazolam

may increase the QTc-prolonging effect of each other when combined

zotepine

may increase the QTc-prolonging effect of each other when combined

lemborexant

may increase the QTc-prolonging effect of each other when combined

hydroxychloroquine

may enhance the QTc-prolonging effect of each other when combined

sparfloxacin

may enhance the QTc-prolonging effect of each other when combined

alfentanil 

alfentanil: they may enhance the serum concentration of CYP3A Inhibitors

avanafil 

avanafil: they may enhance the serum concentration of CYP3A Inhibitors

budesonide 

budesonide: they may enhance the serum concentration of CYP3A Inhibitors

bromocriptine 

bromocriptine: they may enhance the serum concentration of CYP3A Inhibitors

cilostazol 

cilostazol: they may enhance the serum concentration of CYP3A Inhibitors

cisapride 

cisapride: they may enhance the serum concentration of CYP3A Inhibitors

dapoxetine 

dapoxetine: they may enhance the serum concentration of CYP3A Inhibitors

daridorexant 

daridorexant: they may enhance the serum concentration of CYP3A Inhibitors

eliglustat 

eliglustat: they may enhance the serum concentration of CYP3A Inhibitors

encorafenib 

encorafenib: they may enhance the serum concentration of CYP3A Inhibitors

eplerenone 

eplerenone: they may enhance the serum concentration of CYP3A Inhibitors

fentanyl 

fentanyl: they may enhance the serum concentration of CYP3A Inhibitors

ivacaftor 

ivacaftor: they may enhance the serum concentration of CYP3A Inhibitors

lumateperone 

lumateperone: they may enhance the serum concentration of CYP3A Inhibitors

mitapivat 

mitapivat: they may enhance the serum concentration of CYP3A Inhibitors

naloxegol 

naloxegol: they may enhance the serum concentration of CYP3A Inhibitors

indoramin

may enhance the antihypertensive effect of other alpha1-Blockers

bunazosin (Not available in the United States)

may enhance the antihypertensive effect of other alpha1-Blockers

terazosin

may enhance the antihypertensive effect of other alpha1-Blockers

prazosin

may enhance the antihypertensive effect of other alpha1-Blockers

alfuzosin

may enhance the antihypertensive effect of other alpha1-Blockers

moexipril

QTc-prolongers increase the effect of other QTc-prolonging agents

voriconazole

QTc-prolongers increase the effect of other QTc-prolonging agents

nelfinavir

QTc-prolongers increase the effect of other QTc-prolonging agents

alfuzosin

QTc-prolongers increase the effect of other QTc-prolonging agents

ergonovine

may increase the levels of serum concentration of ergot derivatives

cabergoline

may increase the levels of serum concentration of ergot derivatives

dihydroergocornine

may increase the levels of serum concentration of ergot derivatives

dihydroergocristine

may increase the levels of serum concentration of ergot derivatives

dihydroergotamine

may increase the levels of serum concentration of ergot derivatives

mibefradil

may increase the QTc-prolonging effect of each other when combined

fluconazole

may increase the QTc-prolonging effect of each other when combined

ritonavir

may increase the QTc-prolonging effect of each other when combined

foscarnet

may increase the QTc-prolonging effect of each other when combined

sorafenib

may increase the QTc-prolonging effect of each other when combined

terfenadine

it may enhance the QTc-prolonging effect of terfenadine

nilotinib

may enhance the QTc-prolonging effect of Nilotinib

bromeperidol

it decreases the effect of hypotension on blood-lowering agents

aripiprazole 

CYP2D6 inhibitors increase the concentration of aripiprazole in the serum

roflumilast 

they decrease the concentration of active metabolites of roflumilast in the serum

fexinidazole 

it increases the concentration of CYP3A4 substrates in the serum

fusidic acid 

it increases the concentration of CYP3A4 substrates in serum

eletriptan 

may increase the levels of serum concentration of eletriptan

alosetron 

they increase the concentration of alosetron in the serum

fexinidazole 

bradycardia causing agents increase the arrhythmia-causing effect of fexinidazole

moxifloxacin 

may increase the Qtc prolonging effect

acalabrutinib 

may enhance the serum concentration

bromeperidol 

may increase the hypotensive effect of anti-hypertensive agents

moexipril

QTc-prolongers increase the effect of other QTc-prolonging agents

voriconazole

QTc-prolongers increase the effect of other QTc-prolonging agents

nelfinavir

QTc-prolongers increase the effect of other QTc-prolonging agents

alfuzosin

QTc-prolongers increase the effect of other QTc-prolonging agents

dantrolene 

may have an increased hyperkalemic effect when combined with calcium channel blockers

indoramin

may have an increased hypotensive effect when combined with calcium channel blockers

bunazosin (Not available in the United States)

may have an increased hypotensive effect when combined with calcium channel blockers

terazosin

may have an increased hypotensive effect when combined with calcium channel blockers

labetalol 

may have an increased hypotensive effect when combined with calcium channel blockers

prazosin

may have an increased hypotensive effect when combined with calcium channel blockers

infigratinib 

they decrease the concentration of active metabolites of infigratinib in the serum

pimozide 

CYP3A4 inhibitors increase the concentration of pimozide in the serum

iloperidone 

they decrease the concentration of active metabolites of iloperidone in the serum

tafamidis 

may enhance the serum concentration of tafamidis

dantrolene 

May enhance the hyperkalemic effect when combined with Calcium Channel Blockers

citalopram 

may have an increased QTc-prolonging effect when combined with citalopram

entrectinib 

may have an increased QTc-prolonging effect when combined with QT-prolonging agents

fexinidazole 

may have an increased QTc-prolonging effect when combined with QT-prolonging agents

flupentixol 

may have an increased QTc-prolonging effect when combined with flupentixol

nilotinib 

may have an increased QTc-prolonging effect when combined with nilotinib

pazopanib 

may have an increased QTc-prolonging effect when combined with pazopanib

fezolinetant 

may enhance the serum concentration when combined

fexinidazole 

may decrease the therapeutic effect when combined with etofylline

lurbinectedin 

they decrease the concentration of lurbinectedin in the serum

clarithromycin 

QT-prolonging agents (Highest Risk) may increase clarithromycin's ability to prolong QTc

pimozide 

May increase the QTc-prolonging effect of QT-prolonging Agents

sertindole 

may increase the QTc-prolonging effect of QT-prolonging Agents

taurursodiol 

may diminish the concentration of serum when combined with CYP1A2 substrates

agomelatine 

agomelatine: they may enhance the serum concentration of CYP1A2 Inhibitors

duloxetine 

duloxetine: they may enhance the serum concentration of CYP1A2 Inhibitors

melatonin 

melatonin: they may enhance the serum concentration of CYP1A2 Inhibitors

mexiletine 

mexiletine: they may enhance the serum concentration of CYP1A2 Inhibitors

ramelteon 

ramelteon: they may enhance the serum concentration of CYP1A2 Inhibitors

tasimelteon 

tasimelteon: they may enhance the serum concentration of CYP1A2 Inhibitors

promazine 

thiazide and it’s like diuretics increase the effect of QTc prolongation

quinidine gluconate 

May enhance the QTc-prolonging effect of QT-prolonging Class IA Antiarrhythmics

quinidine gluconate 

may increase the serum concentration of each other when combined

nandrolone decanoate

may increase the hypertensive effect when combined with androgens

piperaquine 

piperaquine: they may increase the QTc-prolonging effect of QTc-prolonging Agents

probucol 

probucol: they may increase the QTc-prolonging effect of QTc-prolonging Agents

quetiapine 

quetiapine: they may increase the QTc-prolonging effect of QTc-prolonging Agents

ribociclib 

ribociclib: they may increase the QTc-prolonging effect of QTc-prolonging Agents

sparfloxacin 

sparfloxacin: they may increase the QTc-prolonging effect of QTc-prolonging Agents

thioridazine 

thioridazine: they may increase the QTc-prolonging effect of QTc-prolonging Agents

fexinidazole 

fexinidazole: they may enhance the serum concentration of CYP3A4 inhibitors

fusidic acid 

fusidic acid: they may enhance the serum concentration of CYP3A inhibitors

pyronaridine

May increase the QTc-prolonging effect of each other when combined

atovaquone and proguanil

May increase the QTc-prolonging effect of each other when combined

artemether/lumefantrine

May increase the QTc-prolonging effect of each other when combined

amobarbital

May increase the QTc-prolonging effect of each other when combined

dapsone

May increase the QTc-prolonging effect of each other when combined

mibefradil

may increase the QTc-prolonging effect of each other when combined

magnesium sulfate 

may increase the QTc-prolonging effect of each other when combined

ajmaline

may increase the QTc-prolonging effect of each other when combined

acebutolol

may increase the QTc-prolonging effect of each other when combined

digitoxin

may increase the QTc-prolonging effect of each other when combined

trabectedin 

trabectedin: they may diminish the serum concentration of CYP3A Inhibitors

levodopa

it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics

ketamine

it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics

lidocaine

it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics

morphine

it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics

procaine benzylpenicillin

it may enhance the QTc-prolonging effect of QT-Prolonging Anesthetics

primidone

may enhance the hypotensive effect of blood Pressure Lowering Agents

phenobarbital

may enhance the hypotensive effect of blood Pressure Lowering Agents

amobarbital

may enhance the hypotensive effect of blood Pressure Lowering Agents

butalbital

may enhance the hypotensive effect of blood Pressure Lowering Agents

butabarbital

may enhance the hypotensive effect of blood Pressure Lowering Agents

mibefradil

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

ajmaline

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

acebutolol

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

dronedarone

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

mexiletine

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

hydroxychloroquine

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of Quinolone antibiotics

sparfloxacin

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of Quinolone antibiotics

indoramin

may enhance the hypotensive effect of calcium channel blockers

bunazosin (Not available in the United States)

may enhance the hypotensive effect of calcium channel blockers

terazosin

may enhance the hypotensive effect of calcium channel blockers

prazosin

may enhance the hypotensive effect of calcium channel blockers

alfuzosin

may enhance the hypotensive effect of calcium channel blockers

ouabain

may enhance the AV-blocking effect of cardiac glycosides

digitoxin

may enhance the AV-blocking effect of cardiac glycosides

digoxin

may enhance the AV-blocking effect of cardiac glycosides

ouabain

may enhance the AV-blocking effect of cardiac glycosides

digitoxin

may enhance the AV-blocking effect of cardiac glycosides

digoxin

may enhance the AV-blocking effect of cardiac glycosides

efonidipine

may increase the hypotensive effect

ropivacaine

may increase the hypotensive effect

halothane

may increase the hypotensive effect

fimasartan

may increase the hypotensive effect

indoramin

may increase the hypotensive effect

mibefradil

they increase the QTc prolongation effect of other QT-prolonging agents

hydroxyzine

they increase the QTc prolongation effect of other QT-prolonging agents

tizanidine

they increase the QTc prolongation effect of other QT-prolonging agents

ibandronate

they increase the QTc prolongation effect of other QT-prolonging agents

trazodone

they increase the QTc prolongation effect of other QT-prolonging agents

estropipate

CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs

bazedoxifene/conjugated estrogens

CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs

estradiol valerate

CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs

synthetic conjugated estrogens, a

CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs

synthetic conjugated estrogens, b

CYP3A4 inhibitors (Strong) may increase the serum concentration of estrogen related drugs

botulinum toxin

may enhance the effect of neuromuscular-blocking agents

abobotulinumtoxinA

may enhance the effect of neuromuscular-blocking agents

rimabotulinumtoxinB

may enhance the effect of neuromuscular-blocking agents

daxibotulinumtoxinA

may enhance the effect of neuromuscular-blocking agents

prabotulinumtoxinA

may enhance the effect of neuromuscular-blocking agents

quetiapine

may enhance the effect of antipsychotic agents

thioridazine

may enhance the effect of antipsychotic agents

zotepine

may enhance the effect of antipsychotic agents

cariprazine

may enhance the effect of antipsychotic agents

chlorprothixene

may enhance the effect of antipsychotic agents

chlorpromazine

may enhance the effect of antipsychotic agents

haloperidol

may enhance the effect of antipsychotic agents

pimozide

may enhance the effect of antipsychotic agents

promazine

may enhance the effect of antipsychotic agents

zuclopenthixol

may enhance the effect of antipsychotic agents

ketazolam

may enhance the effect of antipsychotic agents

zotepine

may enhance the effect of antipsychotic agents

lemborexant

may enhance the effect of antipsychotic agents

cariprazine

may enhance the effect of antipsychotic agents

lorpiprazole

may enhance the effect of antipsychotic agents

amisulpride

may enhance the effect of antipsychotic agents

sulpiride

may enhance the effect of antipsychotic agents

sultopride

may enhance the effect of antipsychotic agents

aripiprazole

may enhance the effect of antipsychotic agents

aripiprazole lauroxil

may enhance the effect of antipsychotic agents

asenapine

may enhance the effect of antipsychotic agents

brexpiprazole

may enhance the effect of antipsychotic agents

sertindole

may enhance the effect of antipsychotic agents

ergonovine

may increase the serum concentration of ergot derivatives

ergometrine

may increase the serum concentration of ergot derivatives

methylergometrine

may increase the serum concentration of ergot derivatives

cabergoline

may increase the serum concentration of ergot derivatives

dihydroergocornine

may increase the serum concentration of ergot derivatives

agmatine

may enhance the effect of other bradycardia agents

mibefradil

may enhance the effect of other bradycardia agents

donepezil (Rx)

may enhance the effect of other bradycardia agents

rivastigmine

may enhance the effect of other bradycardia agents

labetalol 

may enhance the effect of other bradycardia agents

amoxapine

may enhance the QTc-prolonging effect of other QT-prolonging Agents

nortriptyline

may enhance the QTc-prolonging effect of other QT-prolonging Agents

apomorphine

may enhance the QTc-prolonging effect of other QT-prolonging Agents

octreotide

may enhance the QTc-prolonging effect of other QT-prolonging Agents

perphenazine

may enhance the hypotensive effect of antipsychotic agents

pimavanserin

may enhance the hypotensive effect of antipsychotic agents

lorpiprazole

may enhance the hypotensive effect of antipsychotic agents

lumateperone

may enhance the hypotensive effect of antipsychotic agents

lurasidone

may enhance the hypotensive effect of antipsychotic agents

paliperidone

may enhance the hypotensive effect of antipsychotic agents

primidone

may have an increased hypotensive effect when combined with anti-hypertensive agents

phenobarbital

may have an increased hypotensive effect when combined with anti-hypertensive agents

amobarbital

may have an increased hypotensive effect when combined with anti-hypertensive agents

butalbital

may have an increased hypotensive effect when combined with anti-hypertensive agents

butabarbital

may have an increased hypotensive effect when combined with anti-hypertensive agents

fluconazole

they increase the risk of other QT prolongers

ritonavir

they increase the risk of other QT prolongers

foscarnet

they increase the risk of other QT prolongers

sorafenib

they increase the risk of other QT prolongers

estropipate

may increase the levels of serum concentration of estrogen derivatives

anastrozole

may increase the levels of serum concentration of estrogen derivatives

bazedoxifene/conjugated estrogens

may increase the levels of serum concentration of estrogen derivatives

esterified estrogens

may increase the levels of serum concentration of estrogen derivatives

estetrol

may increase the levels of serum concentration of estrogen derivatives

ethinyl estradiol

may increase the levels of serum concentration of hormonal contraceptives

etonogestrel

may increase the levels of serum concentration of hormonal contraceptives

ethinylestradiol

may increase the levels of serum concentration of hormonal contraceptives

ethynodiol diacetate

may increase the levels of serum concentration of hormonal contraceptives

pimozide

may have an increased hypotensive effect when combined with antipsychotic agents

risperidone

may have an increased hypotensive effect when combined with antipsychotic agents

promazine

may have an increased hypotensive effect when combined with antipsychotic agents

thioridazine

may have an increased hypotensive effect when combined with antipsychotic agents

zuclopenthixol

may have an increased hypotensive effect when combined with antipsychotic agents

relugolix/​estradiol/​norethindrone

may enhance the hypertensive effect of Androgens

relugolix/estradiol/norethindrone

may enhance the hypertensive effect of Androgens

oxandrolone

may enhance the hypertensive effect of Androgens

nandrolone

may enhance the hypertensive effect of Androgens

fluoxymesterone

may enhance the hypertensive effect of Androgens

perphenazine

may have an increased hypotensive effect when combined with antipsychotic agents

pimavanserin

may have an increased hypotensive effect when combined with antipsychotic agents

chlorpromazine

may have an increased hypotensive effect when combined with antipsychotic agents

pipotiazine

may have an increased hypotensive effect when combined with antipsychotic agents

haloperidol

may have an increased hypotensive effect when combined with antipsychotic agents

iloperidone

may have an increased hypotensive effect when combined with antihypertensive agents

iloprost

may have an increased hypotensive effect when combined with antihypertensive agents

selexipag

may have an increased hypotensive effect when combined with antihypertensive agents

famprofazone

may increase the levels of serum concentration of amphetamines

lisdexamfetamine

may increase the levels of serum concentration of amphetamines

methamphetamine

may increase the levels of serum concentration of amphetamines

dextroamphetamine

may increase the levels of serum concentration of amphetamines

pseudoephedrine

may increase the levels of serum concentration of amphetamines

pancuronium

may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents

botulinum toxin

may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents

abobotulinumtoxinA

may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents

rimabotulinumtoxinB

may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents

daxibotulinumtoxinA

may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents

synthetic conjugated estrogens, a

may increase the serum concentration

synthetic conjugated estrogens, b

may increase the serum concentration

methylergometrine

may increase the serum concentration

lumateperone

may have an increased hypotensive effect when combined with antipsychotic agents

quetiapine

may have an increased hypotensive effect when combined with antipsychotic agents

lurasidone

may have an increased hypotensive effect when combined with antipsychotic agents

promethazine

may have an increased hypotensive effect when combined with antipsychotic agents

mesoridazine

may have an increased hypotensive effect when combined with antipsychotic agents

fluconazole

may increase the QTc-prolonging effect

ritonavir

may increase the QTc-prolonging effect

foscarnet

may increase the QTc-prolonging effect

sorafenib

may increase the QTc-prolonging effect

valrubicin

may increase the levels of serum concentration

doxorubicin

may increase the levels of serum concentration

epirubicin

may increase the levels of serum concentration

mitoxantrone

may increase the levels of serum concentration

mitomycin

may increase the levels of serum concentration

ziv-aflibercept

may increase the levels of serum concentration

tivozanib

may increase the levels of serum concentration

abemaciclib

may increase the levels of serum concentration

acalabrutinib

may increase the levels of serum concentration

bosutinib

may increase the levels of serum concentration

sacituzumab govitecan

may increase the levels of serum concentration

topotecan

may increase the levels of serum concentration

etoposide

may increase the levels of serum concentration

irinotecan

may increase the levels of serum concentration

teniposide

may increase the levels of serum concentration

sacituzumab govitecan

may increase the levels of serum concentrations

topotecan

may increase the levels of serum concentrations

epirubicin

may increase the levels of serum concentrations

etoposide

may increase the levels of serum concentrations

irinotecan

may increase the levels of serum concentrations

ziv-aflibercept

may increase the levels of serum concentration

dacomitinib

may increase the levels of serum concentration

pacritinib

may increase the levels of serum concentration

asciminib

may increase the levels of serum concentration

pemigatinib

may increase the levels of serum concentration

captopril/hydrochlorothiazide

may have an increased bradycardic effect when combined with other antihypertensive drugs

mibefradil

may have an increased bradycardic effect when combined with other antihypertensive drugs

indoramin

may have an increased bradycardic effect when combined with other antihypertensive drugs

minoxidil topical

may have an increased bradycardic effect when combined with other antihypertensive drugs

amlodipine/atorvastatin

may have an increased bradycardic effect when combined with other antihypertensive drugs

perampanel

may increase the levels of serum concentration

riluzole

may increase the levels of serum concentration

tolazoline

They may increase the hypotensive effect when combined with antihypertensive agents

acetaminophen and phenyltoloxamine

may increase the levels of serum concentration

acetaminophen/ibuprofen

may increase the levels of serum concentration

acetaminophen and caffeine

may increase the levels of serum concentration

acetaminophen/pamabrom

may increase the levels of serum concentration

eptinezumab

may increase the levels of serum concentration

acetaminophen and phenyltoloxamine

may increase the levels of serum concentration

acetaminophen/ibuprofen

may increase the levels of serum concentration

acetaminophen and caffeine

may increase the levels of serum concentration

acetaminophen/pamabrom

may increase the levels of serum concentration

aceclofenac

may increase the levels of serum concentration

acemetacin

may increase the levels of serum concentration

antrafenine

may increase the levels of serum concentration

olsalazine

may increase the levels of serum concentration

salicylamide

may increase the levels of serum concentration

remifentanil

may increase the levels of serum concentration

propoxiphene napsylate

may increase the levels of serum concentration

propoxiphene hydrochloride

may increase the levels of serum concentration

bivalirudin

may increase the levels of serum concentration

argatroban

may increase the levels of serum concentration

acenocoumarol

may increase the levels of serum concentration

apixaban

may increase the levels of serum concentration

rivaroxaban

may increase the levels of serum concentration

cinacalcet

may increase the levels of serum concentration

perphenazine

may increase the QTc-prolonging effect

pimavanserin

may increase the QTc-prolonging effect

quetiapine

may increase the QTc-prolonging effect

thioridazine

may increase the QTc-prolonging effect

zotepine

may increase the QTc-prolonging effect

chlorpromazine

may increase the QTc-prolonging effect

haloperidol

may increase the QTc-prolonging effect

pimozide

may increase the QTc-prolonging effect

promazine

may increase the QTc-prolonging effect

zuclopenthixol

may increase the QTc-prolonging effect

pimozide

may increase the QTc-prolonging effect

risperidone

may increase the QTc-prolonging effect

promazine

may increase the QTc-prolonging effect

thioridazine

may increase the QTc-prolonging effect

zuclopenthixol

may increase the QTc-prolonging effect

maralixibat

may have an increased QTc-prolonging effect when combined with QT-prolonging agents

lenacapavir

may have an increased QTc-prolonging effect when combined with QT-prolonging agents

curcumin

may have an increased QTc-prolonging effect when combined with QT-prolonging agents

glecaprevir

may have an increased QTc-prolonging effect when combined with QT-prolonging agents

caspofungin

may have an increased QTc-prolonging effect when combined with QT-prolonging agents

lenacapavir

may increase the serum concentration

abiraterone

may increase the serum concentration

mibefradil

may increase the serum concentration

isoniazid

may increase the serum concentration

mexiletine

may increase the serum concentration

heparin

may enhance the hyperkalemic effect

enoxaparin

may enhance the hyperkalemic effect

selexipag

may enhance the hyperkalemic effect

desmopressin acetate

may increase the serum concentration

conivaptan

may increase the serum concentration

tolvaptan

may increase the serum concentration

amlodipine/atorvastatin

may increase the serum concentration

fluvastatin

may increase the serum concentration

lovastatin

may increase the serum concentration

pitavastatin

may increase the serum concentration

rosuvastatin

may increase the serum concentration

famprofazone

may decrease the antihypertensive effect when combined with antihypertensive agents

lisdexamfetamine

may decrease the antihypertensive effect when combined with antihypertensive agents

methamphetamine

may decrease the antihypertensive effect when combined with antihypertensive agents

dextroamphetamine

may decrease the antihypertensive effect when combined with antihypertensive agents

pseudoephedrine

may decrease the antihypertensive effect when combined with antihypertensive agents

haloperidol

QT-prolonging Agents may enhance the QTc-prolonging effect of haloperidol

levoketoconazole

it may enhance the QTc-prolonging effect of levoketoconazole

alfuzosin

alfuzosin may enhance the hypotensive effect of Blood Pressure Lowering Agents

zotepine

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

cariprazine

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

chlorprothixene

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

lorpiprazole

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

lumateperone

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

zuclopenthixol

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

chlorpromazine

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

haloperidol

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

pimozide

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

promazine

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

fluspirilene

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

ziprasidone

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

ketazolam

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

zotepine

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

lemborexant

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

amisulpride

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

sulpiride

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

sultopride

antihypertensive drugs may enhance the hypotensive effect of antipsychotic Agents

fingolimod

fingolimod may enhance the QTc-prolonging effect of QT-prolonging Agents

fexinidazole

fexinidazole may enhance the QTc-prolonging effect of QT-prolonging Agents

moxifloxacin

may enhance the QTc-prolonging effect of Moxifloxacin

duloxetine

may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents

trazodone

may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents

trimipramine

may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents

venlafaxine

may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents

vilazodone

may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents

mibefradil

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

fluconazole

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

ritonavir

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

foscarnet

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

sorafenib

QT-prolonging Miscellaneous Agents may enhance the QTc-prolonging effect of anti-arrhythmics

diphenhydramine/ibuprofen

NSAIDs May diminish the anti-hypertensive effect of Beta-Blockers

meclofenamate

NSAIDs May diminish the anti-hypertensive effect of Beta-Blockers

aspirin

NSAIDs May diminish the anti-hypertensive effect of Beta-Blockers

floctafenine

NSAIDs May diminish the anti-hypertensive effect of Beta-Blockers

sulindac

NSAIDs May diminish the anti-hypertensive effect of Beta-Blockers

aminophylline

may enhance the hypotensive effect of Blood Pressure Lowering Agents

amrinone

may enhance the hypotensive effect of Blood Pressure Lowering Agents

roflumilast

may enhance the hypotensive effect of Blood Pressure Lowering Agents

iloperidone

may enhance the hypotensive effect of Blood Pressure Lowering Agents

iloprost

may enhance the hypotensive effect of Blood Pressure Lowering Agents

selexipag

may enhance the hypotensive effect of Blood Pressure Lowering Agents