morphine

DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

>10% 

Pruritus  

Urinary retention  

Constipation  

Headache  

Somnolence  

1-10% 

Abdominal pain  

Asthenia  

Backache  

Depression  

Diarrhea  

Dyspnea  

Fever  

Insomnia  

Loss of appetite  

Nausea  

Paresthesia  

Peripheral edema  

Rash  

Sweating  

Xerostomia  

Respiratory depression  

Anxiety  

Dizziness  

Abnormal liver function test results  

Amblyopia  

Hiccups  

Orthostatic hypotension  

Syncope  

Urinary retention  

<1% 

Respiratory depression  

Frequency Not Defined 

Anaphylaxis  

Cardiac arrest 

Circulatory depression 

Ileus 

Lightheadedness 

Miosis 

Malaise 

Thinking disturbances 

Myoclonus 

Vertigo 

Shock 

Morphine is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients. 

Pregnancy consideration:  

The drug is not meant for prolonged use during pregnancy. 

Breastfeeding warnings:  

Morphine is secreted in breast milk. 

Pregnancy category: 

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester. 
• Category B: No evidence shows the risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women.    
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a product in humans; Pregnant women must take care of the potential risks. 
• Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms. However, despite potential dangers may be used only in emergency cases for potential benefits. 
• Category X: Drugs listed in this category outweigh the risks over the benefits. The drug is not for pregnant women. 
• Category N: No data is available for the drug under this category. 

 

Patient information leaflet 

Generic Name:  morphine 

Pronounced: mor-feen 

Why do we use morphine? 

Morphine treats acute and chronic pain.