Cystathionine γ-Lyase Identified as a Key Regulator of Memory and Learning
January 1, 2026
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Brand Name :
Bactroban nasal, Bactroban, centany
Synonyms :
Class :
Anti-bacterial
Brand Name :
Bactroban nasal, Bactroban, centany
Synonyms :
Class :
Anti-bacterial
Dosage Forms & Strengths
Topical ointment
2%
Nasal ointment
2%
2% ointment applied every 8 hours in the affected area for ten days
2% ointment applied every 8 hours in the affected area
Intranasal
One-half of the ointment applied to each nostril every 12 hours for five days from a single-use tube
Dosage Forms & Strengths
Topical ointment
2%
Nasal ointment
2%
2% ointment applied every 8 hours in the affected area for ten days
>2 months: 2% ointment applied every 8 hours in the affected area
>12 years: One-half of the ointment applied to each nostril every 12 hours for five days from a single-use tube
Refer adult dosing
Actions and spectrum:
Actions:
Mupirocin works as an antibiotic. It stops bacteria from making proteins. These proteins help bacteria grow. Mupirocin blocks this process. Without the proteins, bacteria can’t survive. They die. Mupirocin targets protein production in bacteria. This kills the bacteria causing infections. So, mupirocin treats bacterial infections well.
Spectrum:
Mupirocin battles germs, particularly skin infections. It works against common bacteria like strep and staph. This antibiotic tackles a wide range of germs. It handles infections from gram-positive and gram-negative bacteria well. Mupirocin is versatile for different bacterial skin infections. So, it helps manage and cure many skin problems caused by various germs.
Frequency defined:
1-10%
Cellulitis
Burning
Pruritis
Erythema
Swelling
Urticaria
Stinging
Headache
Tenderness
Secondary wound infection
Pain
Frequently not defined
Ulcerative stomatitis
Abdominal pain
dizziness
Black Box Warning
No special warnings are listed for mupirocin
Contraindication/Caution:
Contraindication:
Hypersensitivity
Caution:
Renal impairment
Dental surgery
Pregnancy
Lactation
Pregnancy consideration:
Lactation:
Pregnancy category:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
<b>Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Mupirocin is an antibacterial drug used to combat bacterial infections. It’s known as pseudomonic acid. The medicine stops bacteria from making proteins they need to survive and grow. This makes mupirocin an effective treatment for bacterial skin infections. Its unique way of working marks it as a novel antibacterial medication. Mupirocin targets and inhibits the synthesis of bacterial proteins that are essential for their survival and reproduction. This special ability enables mupirocin to powerfully fight bacterial infections.
Mupirocin is a novel antibacterial drug, formerly known as pseudomonic acid.
Pharmacodynamics:
Mupirocin is a unique medication that works to stop bacteria from growing. It does this by keeping bacteria from making important proteins. Bacteria need these proteins to live. Mupirocin interrupts the process by blocking RNA synthetase. This critical enzyme helps make proteins in bacteria cells. Without it working properly, bacteria cannot create the proteins needed to survive. The end result is that mupirocin wipes out bacteria causing infections like impetigo. Its targeted attack on protein production proves highly effective against harmful bacteria on the skin.
Pharmacokinetics:
Absorption
Mupirocin does not absorb into the body.
Metabolism
The liver breaks it down into monic acid, which has no effect.
Elimination and excretion
Monic acid then leaves the body through urine. When mupirocin enters the bloodstream directly, it exits the body in 20 to 40 minutes. Monic acid takes 30 to 80 minutes to exit. This shows how mupirocin and monic acid move through and leave the body.
Administration:
Mupirocin is only for skin use. Clean the area well before applying. Let it dry. Follow directions from your doctor. Use the amount they say. Don’t stop using mupirocin early. This could let the infection come back. Don’t put it near your nose, eyes, mouth, or broken skin. If it gets in those areas, rinse with lots of water. These steps help mupirocin work right. They keep it safe when treating skin bacteria.
Patient information leaflet
Generic Name: mupirocin
Pronounced: myu peer’ oh sin
Why do we use mupirocin?
Mupirocin is a medicine used for bacterial skin infections, especially impetigo. As an antibiotic for the skin, it works by fighting bacteria that cause impetigo. It kills the specific germs involved in skin infections. This helps treat impetigo and allows the affected skin areas to heal.
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