nadh

Action and Spectrum

Actions and Spectrum:  

Action: The drug is an electron carrier in cellular respiration. During cellular respiration, glucose is broken down to produce energy in the form of ATP. The drug is involved in this process as it carries electrons from glucose to the electron transport chain, where they are used to generate ATP. 

Spectrum: The absorbance of drug can be used to monitor the progress of enzyme-catalyzed reactions, as the increase or decrease in absorbance can indicate the formation or consumption of drug, respectively. 

Drug Interaction

Adverse Reaction

Frequency not defined. 

None reported 

Black Box Warning

Contraindication / Caution

Contraindication/Caution:  

Mental health conditions  

Bleeding disorders 

Surgery 

Parkinson’s disease 

Pregnancy / Lactation

Pregnancy warnings:     

Pregnancy category: N/A 

Lactation: Excreted into human milk is unknown 

Pregnancy Categories:         

Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester. 

Category B: There were a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.   

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.    

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.    

Category N: There is no data available for the drug under this category

Pharmacology

Pharmacology: 

nadh, or nicotinamide adenine dinucleotide, is a coenzyme that is involved in many cellular processes. It plays a crucial role in cellular respiration and energy production in the body.  

Pharmacodynamics: 

nadh, also known as Nicotinamide Adenine Dinucleotide Hydrate, is an important coenzyme found in cells that plays a crucial role in energy metabolism. It is a reduced form of the coenzyme NAD+, meaning that it has an extra hydrogen ion and two electrons.  

Pharmacokinetics: 

Absorption 

The drug is not orally bioavailable as it is rapidly degraded in the gastrointestinal tract. Therefore, it is typically administered intravenously or as a dietary supplement. 

Distribution 

 Once drug enters the bloodstream, it is rapidly distributed throughout the body, where it is utilized by cells for energy production. 

Metabolism 

 Drug is a coenzyme that participates in metabolic reactions but is not metabolized itself. It is converted to NAD+ (nicotinamide adenine dinucleotide) during the process of cellular respiration. 

Excretion and elimination 

Since drug is not metabolized, it is not excreted from the body as a distinct compound. Instead, it is converted to NAD+ and used up in metabolic reactions. Any excess drug that is not used is excreted in the urine. 

Adminstartion

Administration:   

Dosage: The appropriate dosage of this drug will depend on the individual and the condition being treated.

Patient Information Leaflet

Patient information leaflet 

Generic Name: nadh 

Why do we use nadh?  

Energy production 

Antioxidant activity 

Neuroprotection 

Anti-aging 

Treatment of certain medical conditions