pafolacianine

Brand Name :

Cytalux

Synonyms :

pafolacianine

Class :

Diagnostic Imaging Agents

DRUG INTERACTION

pafolacianine

&

pafolacianine +

it decreases the diagnostic ability of pafolacianine

sulopenem etzadroxil/probenecid

It may enhance the risk of adverse effects when combined with Diagnostic agents

sulopenem (Pending FDA Approval)

It may enhance the risk of adverse effects when combined with Diagnostic agents

It may enhance the risk of adverse effects when combined with Diagnostic agents

It may enhance the risk of adverse effects when combined with Diagnostic agents

vaborbactam

It may enhance the risk of adverse effects when combined with Diagnostic agents

>10%:

Nausea

1-10%:

Vomiting

Abdominal pain

Flushing

Dyspepsia

Chest discomfort

Pruritus

Hypersensitivity

Pafolacianine is contraindicated in patients hypersensitive to the active ingredient.

Pregnancy consideration:

No data is available regarding any fetal defects caused due to drug intake during pregnancy.

Breastfeeding warnings:

No data is available regarding the excretion of the drug in breast milk.

Pregnancy category:

Category A: well-controlled and Satisfactory studies do not show risk to the fetus in the first/later trimester.       
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women       
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.      
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.       
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.       
Category N: There is no data available for the drug under this category

Patient information leaflet

Generic Name: pafolacianine

Pronounced: paf-oh-la-SYE-a-neen

Why do we use pafolacianine?

Pafolacianine is a diagnostic imaging agent. It is used to image ovarian cancer or lung lesions.

LEARNING & CME

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pafolacianine

Brand Name :

Cytalux

Synonyms :

pafolacianine

Class :

Diagnostic Imaging Agents

Dosage forms & Strengths:

Injectable solution:

2 mg/ml

Safety and efficacy are not seen in pediatrics.

DRUG INTERACTION

pafolacianine

&

pafolacianine +

it decreases the diagnostic ability of pafolacianine

sulopenem etzadroxil/probenecid

It may enhance the risk of adverse effects when combined with Diagnostic agents

sulopenem (Pending FDA Approval)

It may enhance the risk of adverse effects when combined with Diagnostic agents

It may enhance the risk of adverse effects when combined with Diagnostic agents

It may enhance the risk of adverse effects when combined with Diagnostic agents

vaborbactam

It may enhance the risk of adverse effects when combined with Diagnostic agents

>10%:

Nausea

1-10%:

Vomiting

Abdominal pain

Flushing

Dyspepsia

Chest discomfort

Pruritus

Hypersensitivity

Pafolacianine is contraindicated in patients hypersensitive to the active ingredient.

Pregnancy consideration:

No data is available regarding any fetal defects caused due to drug intake during pregnancy.

Breastfeeding warnings:

No data is available regarding the excretion of the drug in breast milk.

Pregnancy category:

Category A: well-controlled and Satisfactory studies do not show risk to the fetus in the first/later trimester.       
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women       
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.      
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.       
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.       
Category N: There is no data available for the drug under this category

Patient information leaflet

Generic Name: pafolacianine

Pronounced: paf-oh-la-SYE-a-neen

Why do we use pafolacianine?

Pafolacianine is a diagnostic imaging agent. It is used to image ovarian cancer or lung lesions.

Latest Posts

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November 7, 2025

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November 7, 2025

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medtigo

pafolacianine

Brand Name :

Cytalux

Synonyms :

pafolacianine

Class :

Diagnostic Imaging Agents

Action and Spectrum

Dosing & Uses

Drug Interaction

Adverse Reaction

>10%:

Nausea

1-10%:

Vomiting

Abdominal pain

Flushing

Dyspepsia

Chest discomfort

Pruritus

Hypersensitivity

Black Box Warning

Contraindication / Caution

Pafolacianine is contraindicated in patients hypersensitive to the active ingredient.

Pregnancy / Lactation

Pregnancy consideration:

No data is available regarding any fetal defects caused due to drug intake during pregnancy.

Breastfeeding warnings:

No data is available regarding the excretion of the drug in breast milk.

Pregnancy category:

Category A: well-controlled and Satisfactory studies do not show risk to the fetus in the first/later trimester.       
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women       
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.      
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.       
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.       
Category N: There is no data available for the drug under this category

Pharmacology

Adminstartion

Patient Information Leaflet

Patient information leaflet

Generic Name: pafolacianine

Pronounced: paf-oh-la-SYE-a-neen

Why do we use pafolacianine?

Pafolacianine is a diagnostic imaging agent. It is used to image ovarian cancer or lung lesions.