- March 15, 2022
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Brand Name :
Protonix
Synonyms :
pantoprazole
Class :
Drugs for peptic ulcer & Proton pump inhibitors
gastroesophageal reflux disease (GERD)
Indicated for Erosive Esophagitis Associated With GERD
40 mg orally daily 8-16 weeks; may be increased to 40 mg
when both drugs are combined, there may be a decrease in levels of serum concentration and absorption of erlotinib
it may decrease the serum concentration of belumosudil
it may decrease the serum concentration of bosutinib
interaction with proton pump inhibitors may cause delayed elimination of methotrexate.
interaction with proton pump inhibitors may cause delayed elimination of trimetrexate
when both drugs are combined, there may be an increased level of serum concentration of alpelisib
the serum concentration of acalabrutinib may be reduced by Inhibitors of the Proton Pump (PPIs and PCABs)
it may diminish the therapeutic effect of Immune Checkpoint Inhibitors
it may diminish the therapeutic effect of Immune Checkpoint Inhibitors
it may diminish the therapeutic effect of Immune Checkpoint Inhibitors
It may enhance the effect when combined with tafamidis meglumine
when both drugs are combined, there may be an increased risk of hypomagnesemia
Zidovudine increases the serum concentrations of pantoprazole, dose adjustments may be suggested to avoid toxicity
Tenofovir alafenamide increases the serum concentrations of pantoprazole, dose adjustments may be suggested to avoid toxicity
it may decrease the serum concentration of Atazanavir
Frequency defined:
1%-10%
Abdominal pain
Constipation
Diarrhea
Nausea
Dizziness
Headache
<1%:
Bradycardia
Chest pain
Pruritis
Decreased libido
Diabetes mellitus
Goiter
Abdominal distension
Pregnancy consideration: No adverse effects have been reported in animal reproduction studies. It can be recommended for the treatment of GERD in pregnant women.
Lactation: Pantoprazole can be excreted in breast milk, use with caution.
Patient information leaflet
Generic Name: Pantoprazole
Pronounced: Pen-to-pra-zole
Why do we use pantoprazole?
Pantoprazole is a proton pump inhibitor. It is used to decrease acid secretion in gastric parietal cells and treat esophagitis, acid reflux (GERD), peptic ulcers, and H.pylori infection.
Pregnancy category:
Patient information leaflet
Generic Name: Pantoprazole
Pronounced: Pen-to-pra-zole
Why do we use pantoprazole?
Pantoprazole is a proton pump inhibitor. It is used to decrease acid secretion in gastric parietal cells and treat esophagitis, acid reflux (GERD), peptic ulcers, and H.pylori infection.
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