Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Superin, Natulan, Valdy-P, Praxis, Vorth-P, Valus P, Valdixx, Valeron, Bioval-P, Revaldo-P
Synonyms :
parecoxib
Class :
Anti-inflammatory drugs and non-Selective COX inhibitors
Brand Name :
Superin, Natulan, Valdy-P, Praxis, Vorth-P, Valus P, Valdixx, Valeron, Bioval-P, Revaldo-P
Synonyms :
parecoxib
Class :
Anti-inflammatory drugs and non-Selective COX inhibitors
Dosage Forms & StrengthsÂ
Powder for reconstitution, Injection:Â
40 mgÂ
Â
For >18 years: 40 mg IM/IV as an initial dose, 20-40 mg every 6-12 hours followed by initial dose (do not exceed 80 mg)
Dose Adjustments
For hepatic impairment:
Moderate (Child-Pugh score 7-9): 20 mg every 6-12 hours (do not exceed 40 mg/day)
Severe (Child-Pugh score >9): Not recommended
may enhance the serum concentration of CYP2C9 inhibitors
When loracarbef is used together with parecoxib, the risk or seriousness of nephrotoxicity is enhanced
When parecoxib is used together with sertraline, the risk or seriousness of bleeding may be enhanced
When parecoxib is used together with bufexamac, this leads to enhanced risk or seriousness of adverse outcomes
When parecoxib is used together with nifenazone, this leads to enhanced risk or seriousness of adverse events
Nonsteroidal Anti-Inflammatory Agents may diminish the antihypertensive effect of aliskiren
bile Acid Sequestrants may decrease the absorption of Nonsteroidal Anti-Inflammatory Agents
lapatinib increases the effect of parecoxib by altering the intestinal or hepatic CYP3A4 enzyme metabolism
metronidazole enhances the effect of parecoxib by altering the intestinal or hepatic CYP3A4 enzyme metabolism
SSRIs increase the antiplatelet effect of NSAIDs
Frequency defined:Â Â
Ulcer Â
Gastrointestinal bleedingÂ
Jaundice Â
Abnormal live functionÂ
Heart failureÂ
Heart attackÂ
Slow heart rateÂ
Swelling Â
RashÂ
Back painÂ
Agitation Â
Decreased urinationÂ
Pregnancy consideration: Parecoxib is known to cause some serious birth defects, avoid it during pregnancy. Â
Lactation: Parecoxib can be excreted in the breast milk, do not administer to breastfeeding women   Â
Pregnancy category:Â
Patient information leafletÂ
Generic Name: ParecoxibÂ
Pronounced: par-i-coks-ib Â
Why do we use parecoxib?Â
Parecoxib is used for postoperative pain.Â
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