parsley

Action and Spectrum

Actions and Spectrum: 

parsley is recognized for its ability to act as a diuretic, which can enhance the production of urine and facilitate the removal of excess fluids from the body.  

parsley is rich in antioxidants, such as vitamin C and flavonoids, which have the potential to counteract harmful free radicals in the body.  

Traditionally, parsley has been used as a digestive aid due to its carminative properties, which can help alleviate bloating and reduce gas.  

Thanks to its diuretic properties, parsley can aid in promoting kidney function by facilitating urine production and assisting in the elimination of waste materials.  

The digestive properties of parsley have the potential to enhance digestion, alleviate digestive discomfort, and decrease bloating.  

The diuretic effect of parsley may aid in the removal of toxins from the body, thereby supporting overall detoxification processes. 

Drug Interaction

Adverse Reaction

Frequency not defined  

None  

Black Box Warning

Black Box Warning 

parsley, being an herbal supplement, do not have black box warning. 

Contraindication / Caution

Contraindication/Caution: 

• People with a history of allergies or hypersensitivity to parsley must steer clear of parsley supplements as they may encounter allergic reactions. 
• While parsley’s diuretic characteristics may prove advantageous for some people, those with pre-existing kidney issues like kidney stones or impaired kidney function should take parsley supplements with care. 
• Pregnant or lactating women should avoid parsley supplements as they may lead to uterine stimulation and have detrimental effects on pregnancy. 

Pregnancy / Lactation

Pregnancy warnings:     

Pregnancy category: N/A 

Lactation: N/A 

Pregnancy Categories:         

Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester. 

Category B: There were lack of studies on pregnant women and no evidence of risk to the foetus in animal experiments.   

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.    

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.    

Category N: There is no data available for the drug under this category

Pharmacology

Pharmacology 

parsley comprises volatile compounds, namely myristicin, apiol, and limonene, that are responsible for its pharmacological effects.  

parsley is abundant in flavonoids, like apigenin, luteolin, and quercetin. These constituents exhibit antioxidant and anti-inflammatory characteristics, they eliminate free radicals, safeguard cells from oxidative impairment, and have potential in mitigating inflammation in the body.  

Pharmacodynamics 

The diuretic characteristics of parsley are well-known and are mainly due to elements such as myristicin and apiol. These constituents have the potential to amplify urine production by heightening the flow of blood in the renal system and the glomerular filtration rate. This, in turn, results in the expulsion of more fluids and waste products from the body. 

parsley is rich in flavonoids, specifically apigenin and luteolin, as well as vitamin C, which function as antioxidants. These elements are capable of scavenging and neutralizing harmful free radicals, thereby reducing oxidative stress and safeguarding cells against damage caused by reactive oxygen species. 

Pharmacokinetics 

Absorption   

When ingested as an herbal remedy, the effective elements of parsley are taken in through the digestive system. The degree of absorption may fluctuate based on variables such as the arrangement of the remedy, the existence of other food components, and personal differences. 

Distribution 

After absorption, the elements of parsley are dispersed throughout the body via the circulatory system. The dispersion may be influenced by various factors, including the physical and chemical properties of the active compounds and their attraction to tissues or organs. 

Metabolism 

The breakdown of the active components in parsley can take place in the liver and other bodily tissues. Unique enzymes may play a role in breaking down distinct compounds. The breakdown of parsley’s constituents can lead to the creation of metabolites that could exhibit diverse pharmacological characteristics from their parent compounds. 

Elimination and excretion 

The removal of parsley and its metabolites from the body is mainly through feces and urine. The diuretic attributes of parsley can help with the expulsion of its constituents by elevating urine output. The degree and speed of expulsion can differ based on personal factors, metabolism, and other physiological mechanisms. 

Adminstartion

Administration:  

parsley supplements are frequently enclosed in capsules or tablets. These can be ingested by mouth with water or as indicated on the product packaging. 

Certain parsley supplements can be obtained as a liquid extract. These extracts are commonly condensed and can be blended with water or other drinks. 

Powdered formulations may also be an option for parsley supplements. 

Patient Information Leaflet

Patient information leaflet 

Generic Name: parsley  

Why do we use parsley? 

parsley possesses diuretic characteristics that are beneficial in increasing urine production and sustaining kidney performance. This herb may facilitate the removal of undesirable substances from the body and aid in maintaining the urinary system’s health. 

parsley has been a long-standing remedy for digestive issues. It can potentially enhance digestion, relieve bloating and gas, and stimulate the appetite. 

parsley supplements may help in purging harmful toxins and waste elements from the body, thanks to its diuretic properties.