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Brand Name :
denavir
Synonyms :
penciclovir
Class :
Anti virals,topical
Dosage Forms & Strengths
Cream
0.1%
After the first onset of symptoms, apply every 2 hours for four days while awake
Dosage Forms & Strengths
Cream
0.1%
<12 years: Safety and efficacy not established
>12 years: After the first onset of symptoms, apply every 2 hours for four days while awake
may decrease the therapeutic effects of antiherpetic antivirals
may decrease the serum concentration of Polyvalent Cation Containing Products
Frequency defined:
>10%
Mild erythema
1-10%
Headache
Reaction at the application site
<1%
Erythematous rash
Oropharyngeal edema
Parosmia
Pain
Taste perversion
Local anesthesia
Local edema
Paresthesia
Skin discoloration
Urticaria
Pregnancy consideration: The medicine is not absorbed systemically after topical treatment, and maternal use is not predicted to result in fetal exposure to the drug
Lactation: Excretion of the drug in human breast milk is unknown
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient information leaflet
Generic Name: penciclovir
Pronounced: pen-SYE-kloe-vir
Why do we use penciclovir?
It is used in the treatment of recurrent herpes simplex labialis