2025 Guidelines for the Evaluation and Management of Adults With Congenital Heart Disease
December 19, 2025
Brand Name :
Vitabact
Synonyms :
picloxydine
Class :
Eye anti-infectives; Antiseptics
Dosage Forms & Strengths
Ophthalmic solution
0.05%
0.05% through ophthalmic route
No data is available
Refer to the adult dosing
Actions and Spectrum:
picloxydine is an anti-infective agent used in the treatment of eye infections. It has bactericidal activity.
Frequency not defined
Corneal damage
Irritation
Black Box Warning:
None
Contraindication/Caution:
Contraindications:
Cautions:
Pregnancy consideration:
The drug should be avoided during pregnancy.
Breastfeeding warnings:
It is unknown whether picloxydine is secreted in the breast milk.
Pregnancy category:
Category A: Well-controlled and satisfactory studies show no risk to the fetus in the initial or later trimester.
Category B: There was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology:
picloxydine is an anti-infective agent used in the treatment of eye infections. It has bactericidal activity.
Pharmacodynamics:
picloxydine is an anti-infective agent used in the treatment of eye infections. It has bactericidal activity.
Pharmacokinetics:
Absorption:
picloxydine is absorbed through the lachrymal route.
Distribution:
It.
Metabolism:
The metabolism is unknown.
Elimination and Excretion:
The drug is excreted through the renal route.
Administration:
picloxydine is administered through the ophthalmic route as eye drops.
Patient information leaflet
Generic Name: picloxydine
Pronounced as: pik-lox-i-deen
Why do we use picloxydine?
picloxydine is an antiseptic of bisbiguanide class.
It works bacteriostatically on the various gram-positive and gram-negative bacteria in conjunctiva.
It is used as an antiseptic for various eye infections.