pralurbactam

Action and Spectrum

Actions and Spectrum:   

Pralurbactum inhibits the beta lactamase enzymes and enhances the effectiveness against the beta lactamase bacteria.  

Spectrum of Activity:   

Pralurbactum when combined with beta lactam antibiotics, targets the bacteria by producing extended spectrum beta-lactamases of urinary tract infections.   

Drug Interaction

Adverse Reaction

Frequency not defined 

Not reported 

Black Box Warning

 None 

Contraindication / Caution

Contraindications/caution:   

There is no documented data.  

Pregnancy / Lactation

Pregnancy Warnings: 

Pregnancy category: Not available   

Lactation: Excretion of drug into breast milk is unknown 

Pregnancy Categories:   

Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.   

<b>Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.   

Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.   

Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.   

Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.   

Category N: There is no data available for the drug under this category.    

Pharmacology

Pharmacology:   

Pralurbactam containing drugs targets extended-spectrum beta-lactamases against Pseudomonas aeruginosa, Enterobacteriaceae, and Acinetobacter baumannii.   

Pharmacokinetics:   

Absorption   

Pralurbactam is typically administered intravenously for rapid absorption into the bloodstream.   

Distribution   

It is distributed throughout the body.    

Metabolism   

There is no sufficient data available.  

Elimination and Excretion   

The drug gets excreted through kidneys.  

Adminstartion

Administration: 

There is no sufficient data available.  

Patient Information Leaflet

Patient information leaflet 

Generic Name: pralurbactam   

Why do we use Pralurbactam?   

pralurbactam is used to treat multidrug-resistant bacteria infections.