DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Frequency defined:  

>10%: 

Headache 

Severe hypoglycemia 

Nausea 

Anorexia  

Vomiting  

Accidental injury   

1% to 10%: 

Fatigue 

Abdominal pain 

Cough 

Pharyngitis 

Pancreatitis  

Arthralgia  

Pregnancy consideration: pramlintide is currently not recommended for treatment of diabetes mellitus in pregnant women.  

Lactation: excretion of pramlintide in breast milk is not known.  

Pregnancy category: 

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester. 
• Category B: There is no evidence of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women. 
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women 
• Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits. 
• Category X: Drugs listed in this category outweigh risks over benefits. These category drugs should be prohibited for pregnant women. 
• Category N: There is no data available for the drug under this category. 

Patient information leaflet 

Generic Name: Pramlintide 

Pronounced: pramlintide  

Why do we use pramlintide? 

Pramlintide is used for the treatment of diabetes mellitus type 1 and type 2.