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Brand Name :
N/A
Synonyms :
proximadiol
Class :
Sesquiterpenoids, Terpenoids
Brand Name :
N/A
Synonyms :
proximadiol
Class :
Sesquiterpenoids, Terpenoids
Dosage Forms & Strengths
Effervescent Granules (capsules)
8 mg
Urinary Tract Infections
It is indicated in the treatment of UTI and kidney stones
Available in the combination form
Combination form:
It is available as active ingredient in proximal compound with other two ingredients such as 18.6 mg extract of halfa bar which is equivalent to 8 mg of this drug and 6 and 1 mg of hexamine and piperazine citrate
Recommended dose is 2 capsules per day two or three times after food
It is recommended that patients suffering from urinary lithiasis drink a lot of fluids as this will aid in the expulsion of the calculi
Dose Adjustments
Limited data is available
Safety and efficacy are not established
Refer to the adult dosing
Actions and Spectrum:
Actions:
Blumea balsamifera leaves and Zingiber mekongense rhizomes yielded proximadiol. Proximadiol lacks antibacterial or antiviral effects. In micromolar amounts, it inhibits receptor (platelet-activating factor) binding to platelets.
Spectrum:
Proximol Compound granules treat urinary tract, threadworm, pinworm, and roundworm infections.
Frequency not defined
Vomiting
Stomach upset
Dysuria
Feeling of sickness
Jerky movement
Myoclonic contractions
Pruritis
Muscular incoordination
Headache
Diarrhea
Black Box Warning:
Proximol Compound Granules cause hypotension, fatigue, dizziness, headaches, or sleepiness, it’s unsafe to drive or use heavy machinery.
Contraindication/Caution
Contraindications
Hypersensitivity
Hepatic insufficiency
Renal insufficiency
Epilepsy
Cautions
kidney disease
Renal disease
Pregnancy consideration:
No data available
Breastfeeding warnings:
No data is available
Pregnancy category:
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.
Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: Adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology:
Proximadiol belongs to the class of Sesquiterpenoids.
Pharmacodynamics:
Proximadiol, derived from cymbopogon proximus petroleum ether extract, has antispasmodic properties, and can help with kidney and ureteric stone propulsion.
Pharmacokinetics:
Limited data is available
Administration:
Effervescent granules can be taken orally, either two capsules or five spoonfuls, after eating, often combined with other medications.
Patient information leaflet
Generic Name: proximadiol
Why do we use proximadiol?
Proximadiol fights threadworms, roundworms, pinworms, and urinary tract infections. Its granules contain piperazine, proximadiol, and hexamine, which hinder microorganism growth, causing paralysis in worms and treating infections.
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