One Cup of Coffee a Day Keeps AF Away? Insights from the DECAF Trial
November 10, 2025
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Brand Name :
abthrax
Synonyms :
Raxibacumab
Class :
Monoclonal antibody
Brand Name :
abthrax
Synonyms :
Raxibacumab
Class :
Monoclonal antibody
Dosage Forms & StrengthsÂ
Intravenous solutionÂ
50mg/mlÂ
40
mg/kg
single dose infusion
Intravenous (IV)
for over 2.25 hour
Diphenhydramine should be administered 1 hour before the infusion
Dosage Forms & StrengthsÂ
Intravenous solutionÂ
50mg/mlÂ
15kgs:80mg/kg intravenously
≥15 to 50kg:60mg/kg intravenously
>50kg:40mg/kg intravenously, single dose infusion for 2.25 hour
Diphenhydramine should be administered 1 hour before the infusion
may decrease the therapeutic effects of Fc receptor binding agents
it may enhance the adverse effects when combined with aducanumab
Frequency defined:Â Â
1-10%Â
Pain in extremityÂ
SomnolenceÂ
Rash pruritisÂ
<1%Â
VertigoÂ
FatigueÂ
AnemiaÂ
Muscle spasmÂ
LeukopeniaÂ
Syncope vasovagalÂ
PalpitationsÂ
lymphadenopathyÂ
InsomniaÂ
Pregnancy consideration: Insufficient data availableÂ
Lactation: Excretion of the drug is unknownÂ
Pregnancy category:Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.  Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this categoryÂ
Patient information leafletÂ
Generic Name: raxibacumabÂ
Pronounced: rax” ee bak’ ue mabÂ
Why do we use raxibacumab?Â
It is used to treat inhalational anthrax in adults and pediatricsÂ
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
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