reishi

Action and Spectrum

Actions and Spectrum: 

reishi is frequently categorised as an adaptogenic herb, which means that it supports general balance and resilience while assisting the body in adapting to diverse stimuli. 

reishi has immunomodulatory effects, which means it can support and modulate the immune system’s operation. When appropriate, it might strengthen immunological responses and encourage immune system equilibrium. 

It may improve immunological performance and encourage a healthy immune response. reishi functions as an adaptogen, which may aid the body in coping with stress and foster feelings of serenity and relaxation. 

Drug Interaction

Adverse Reaction

Frequency defined  

None  

Black Box Warning

Black Box Warning 

As an herbal supplement, reishi does not have a black box warning. 

Contraindication / Caution

Contraindication/Caution: 

• reishi may have immune-modulating effects, so it’s important to exercise caution when using reishi alongside immunosuppressive medications.  
• Individuals with known allergies to mushrooms or fungal products should exercise caution when using reishi.  
• It is advisable to discontinue the consumption of reishi at least two weeks prior to undergoing any surgical procedures, as it may have an impact on blood clotting and lead to bleeding complications. 

Pregnancy / Lactation

Pregnancy warnings:     

Pregnancy category: N/A 

Lactation: Excretion into human milk is unknown 

Pregnancy Categories:         

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. 

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology 

reishi is rich in polysaccharides, including beta-glucans, which have been shown to have immunomodulatory effects. The activity of several immune system parts has been demonstrated to be modulated by reishi.  

A balanced immune system can be supported by increasing the generation of immune cells and cytokines that are engaged in immunological responses. 

Pharmacodynamics 

reishi has anti-inflammatory qualities, which may be a result of its bioactive components, such as triterpenes. They may change inflammatory signalling pathways and suppress the synthesis of pro-inflammatory mediators like cytokines and enzymes.  

Antioxidants found in abundance in reishi can scavenge free radicals and lessen oxidative stress. 

Pharmacokinetics 

Absorption   

The bioactive compounds in reishi, such as polysaccharides and triterpenes, need to be absorbed into the bloodstream to exert their effects. 

Distribution 

The compounds from reishi can be distributed throughout the body via the bloodstream.  

Metabolism 

reishi compounds may undergo metabolism in the body, primarily in the liver.  

Elimination and excretion 

The elimination of reishi compounds from the body occurs mainly through renal excretion. 

Adminstartion

Administration:  

reishi is available as an herbal supplement in various forms like tablets, capsules, powders and tinctures. 

Patient Information Leaflet

Patient information leaflet 

Generic Name: reishi 

Why do we use reishi? 

reishi is often used to support and modulate the immune system.  

reishi is used to boost energy levels and enhance vitality.  

reishi has been traditionally used to support liver health and promote detoxification. 

reishi is regarded as an adaptogen, a substance that helps the body adapt to stress and promotes a sense of relaxation.