respiratory syncytial virus (RSV) vaccine

medtigo

respiratory syncytial virus (RSV) vaccine

Brand Name :

Abrysvo

Synonyms :

respiratory syncytial virus (RSV) vaccine

Class :

Vaccines, Inactivated

Action and Spectrum

Actions and Spectrum:

In order to create antibodies against the virus, the respiratory syncytial virus vaccine stimulates the immune system. This aids in either preventing RSV infection or lessening the severity of symptoms if it does. The vaccine may also reduce the possibility of the virus spreading from an infected person to another person.

The RSV vaccine’s range is specialised to the RSV virus, which is a frequent cause of respiratory tract infections in kids, especially those under two years old. The RSV strains, particularly the A and B subtypes of the virus, that are most frequently linked to severe illness, hospitalisation, and mortality, are among those against which the vaccine is intended to provide defence.

Dosing & Uses

Drug Interaction

Adverse Reaction

Frequency defined

1-10%

Injection site pain, mild (9.4%)

Joint pain, any (7.5%)

Diarrhea, any (5.9%)

Fatigue, mild (9.3%)

Diarrhea, mild (4.4%)

Headache, moderate (3.7%)

Joint pain, mild (4.5%)

Muscle pain, moderate (3.5%)

Injection site pain, moderate (1.1%)

Redness, mild (1.5%)

Diarrhea, moderate (1.3%)

Redness, moderate (1.1%)

Joint pain, moderate (2.9%)

Fever, ≥38ºC (1.4%)

Redness, any (2.7%)

Nausea, any (3.4%)

Muscle pain, mild (6.5%)

Headache, mild (9%)

Nausea, mild (2.5%)

Swelling, mild (1.5%)

Fatigue, moderate (5.9%)

>10%

Injection site pain, any (10.5%)

Muscle pain, any (10.1%)

Fatigue, any (15.5%)

Headache, any (12.8%)

<1%

Nausea, mild (0.7%)

Swelling, moderate (0.9%)

Diarrhea, severe (0.1%)

Headache, severe (0.1%)

Swelling, severe (0.1%)

Joint pain, severe (<0.1%)

Fever >38.9-40ºC (<0.1%)

Redness, severe (0.1%)

Fever 38-38.4ºC (0.6%)

Injection site pain, severe (<0.1%)

Muscle pain, severe (0.2%)

Nausea, moderate (0.2%)

Fever >38.4-38.9ºC (0.8%)

Nausea, moderate (0.9%)

Fatigue, severe (0.3%)

Black Box Warning

Black Box Warning:

None

Contraindication / Caution

Contraindication

strong allergic reaction to the vaccination or any of its ingredients after receiving a dose before.
Acute sickness of moderate to severe severity at the time of immunisation
Immunosuppressive or immunodeficiency treatment

Caution

Guillain-Barré syndrome or other neurological conditions in the past
breastfeeding or being pregnant
Persistent illnesses like heart or lung disease

Pregnancy / Lactation

Pregnancy warnings:   

Pregnancy category: N/A

Lactation: Excreted into human milk is unknown

Pregnancy Categories:        

Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.

Category B: There were lack of studies on pregnant women and no evidence of risk to the foetus in animal experiments.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.  

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   

Category N: There is no data available for the drug under this category

Pharmacology

Pharmacology:

Immune systems are induced by RSV vaccine to develop antibodies against the virus. This immune response works to stave against RSV infection or, if it does, lessen the severity of symptoms.

A little portion of the virus possibly a protein or a bit of genetic material that stimulates an immune response may be included in the RSV vaccine. The immune system is trained to detect and respond to RSV in the future because to this antigen presentation.

Pharmacodynamics:

Immune systems are induced by RSV vaccine to develop antibodies against the virus. The immune system produces antibodies, which are proteins, in response to a particular antigen (such as a viral protein). Induction of RSV-specific antibodies by RSV vaccine is anticipated to help prevent RSV infection or lessen the severity of symptoms if infection does occur.

Pharmacokinetics:

Absorption 

RSV vaccines are often given intravenously, bypassing the digestive system and going straight to the circulation. The formulation of the vaccine, the place of injection, and the recipient’s immunological response are only a few examples of the variables that may affect the speed and degree of absorption.

Distribution 

The RSV vaccine is delivered to numerous tissues and organs all over the body after it has entered the circulation. Factors including the vaccine’s composition and the recipient’s immunological response may have an impact on how the vaccine is administered.

Metabolism

Immune systems are induced by RSV vaccine to develop antibodies against the virus. Although the body does not metabolize the vaccine itself, the immunological response it induces may include intricate metabolic processes.

Elimination and Excretion 

It is not anticipated that RSV vaccine would stay in the body for a very long time. Instead, the immunological response brought on by the vaccination may offer months or even years of protection against RSV infection.

Adminstartion

Administration: 

Injections are often used to give RSV vaccine. Depending on the vaccine composition, the injection may be administered intramuscularly or subcutaneously.

Patient Information Leaflet

Patient information leaflet

Generic Name: respiratory syncytial virus (RSV) vaccine

Why do we use respiratory syncytial virus (RSV) vaccine?

RSV is a frequent cause of respiratory disease in young children, and a potent vaccine might help in reducing the number of hospitalizations and illnesses attributable to RSV.

An additional layer of protection from a severe RSV infection may be offered by an RSV vaccine for infants who were born prematurely or who have certain underlying medical issues.

respiratory syncytial virus (RSV) vaccine

No data available for drug.

DRUG INTERACTION

respiratory syncytial virus (RSV) vaccine

&

respiratory syncytial virus (RSV) vaccine +

Contraindicated

Serious Use Alternative

Monitor Closely

Minor

respiratory syncytial virus (RSV) vaccine

No data available for drug.

DRUG INTERACTION

respiratory syncytial virus (RSV) vaccine

&

respiratory syncytial virus (RSV) vaccine +

Contraindicated

Serious Use Alternative

Monitor Closely

Minor

medtigo

respiratory syncytial virus (RSV) vaccine

Brand Name :

Synonyms :

Class :

Action and Spectrum

Dosing & Uses

Drug Interaction

Adverse Reaction

Black Box Warning

Contraindication / Caution

Pregnancy / Lactation

Pharmacology

Adminstartion

Patient Information Leaflet

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