risedronate

Action and Spectrum

Drug Interaction

Adverse Reaction

>10%: 

Arthralgia  

Diarrhea  

Headache  

Nausea  

Constipation  

Rash  

Abdominal pain  

Hypertension  

Dyspepsia  

1-10%: 

Flulike syndrome  

Depression  

Chest pain  

Dizziness  

Pharyngitis 

Rhinitis  

Prostatic hyperplasia  

Hypocalcemia  

Dyspnea  

Gastritis  

Nephrolithiasis 

Hypophosphatemia  

Arrhythmia 

<1%: 

Diaphyseal femur 

Dysphagia 

Esophageal cancer 

Esophageal ulcer 

Femur fracture 

Gastric and duodenal ulcer 

Osteonecrosis 

Black Box Warning

Contraindication / Caution

Risedronate is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients. 

Pregnancy / Lactation

Pregnancy consideration:  

The data reported is insufficient to know the risk of the drug in pregnant females. 

Breastfeeding warnings:  

No data is available regarding the excretion of the drug in breast milk.  

Pregnancy category: 

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester. 
• Category B: No evidence shows the risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women.    
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a product in humans; Pregnant women must take care of the potential risks. 
• Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms. However, despite potential dangers may be used only in emergency cases for potential benefits. 
• Category X: Drugs listed in this category outweigh the risks over the benefits. The drug is not for pregnant women. 
• Category N: No data is available for the drug under this category. 

Pharmacology

Adminstartion

Patient Information Leaflet

Patient information leaflet 

Generic Name:  risedronate 

Pronounced: rise-dro-nate 

Why do we use risedronate? 

Risedronate is a calcium metabolism modifier. It treats osteoporosis in men and women.