Brand Name :
Aarel (QA)
Synonyms :
sodium lactate
Class :
Alkalinizing Agents, Urinary pH modifiers, Minerals, and electrolytes
Dosage Forms & Strengths
infusion solution
5 mEq/mL or 560 mg/mL
Indicated for Alkalinizing Agent
Depending upon the severity of the metabolic acidosis, the dosage is directed by a physician
Dosage Forms & Strengths
Infusion solution
1000mL
500mL
Indicated for Alkalinizing Agent
Depending upon the severity of the metabolic acidosis, the dosage is directed by a physician
Refer the adult dosing
may decrease the serum concentration of Quinolones
may decrease the serum concentration of Quinolones
it may decrease the excretion of amphetamines
may diminish the excretion of amphetamines
It may diminish the excretion when combined with alkalinizing agents.
it may decrease the serum concentration of Minerals
it may decrease the serum concentration of Minerals
it may decrease the serum concentration of Minerals
it may decrease the serum concentration of Minerals
it may decrease the serum concentration of Minerals
may increase the antiplatelet effect of agents with antiplatelet properties
may increase the antiplatelet effect of agents with antiplatelet properties
may increase the antiplatelet effect of agents with antiplatelet properties
may increase the antiplatelet effect of agents with antiplatelet properties
may increase the antiplatelet effect of agents with antiplatelet properties
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the arrhythmogenic effect of cardiac glycosides
may increase the levels of serum concentration of alpha-/beta-agonists
may reduce the rate of excretion of amphetamines
may reduce the rate of excretion of amphetamines
may reduce the rate of excretion of amphetamines
may reduce the rate of excretion of amphetamines
may reduce the rate of excretion of amphetamines
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
may decrease the levels of serum concentration of amphetamines
May reduce the levels of serum concentration of amphetamines
May reduce the levels of serum concentration of amphetamines
May reduce the levels of serum concentration of amphetamines
May reduce the levels of serum concentration of amphetamines
May reduce the levels of serum concentration of amphetamines
May increase the levels of serum concentration
may decrease the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the serum concentration
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
may increase the risk of adverse effect
alkalinizing agents: they may enhance the serum concentration of Alpha or Beta-Agonists
alkalinizing agents: they may enhance the serum concentration of Alpha or Beta-Agonists
it may increase the level of serum concentration of memantine
it May enhance the antiplatelet effect of Agents with antiplatelet Properties
it May enhance the antiplatelet effect of Agents with antiplatelet Properties
it May enhance the antiplatelet effect of Agents with antiplatelet Properties
it May enhance the antiplatelet effect of Agents with antiplatelet Properties
it May enhance the antiplatelet effect of Agents with antiplatelet Properties
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the rate of excretion of amphetamines
may decrease the serum concentration of minerals
may decrease the serum concentration of minerals
hydrocodone/chlorpheniramine/pseudoephedrine
may enhance the serum concentration of alpha/beta agonists
hydrocodone/chlorpheniramine/pseudoephedrine
may decrease the serum concentration of alpha/beta agonists
acrivastine and pseudoephedrine
may increase the serum concentration of alpha/beta agonists
may diminish the serum concentration of amphetamines
may enhance the serum concentration of amantadine
may diminish the serum concentration of amantadine
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
may decrease the serum concentration
mecamylamine: they may enhance the serum concentration of alkalinizing agents
memantine: they may enhance the serum concentration of alkalinizing agents
quinidine: they may enhance the serum concentration of alkalinizing agents
quininie: they may enhance the serum concentration of alkalinizing agents
flecainide: they may diminish the excretion of alkalinizing agents
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
amphetamines: they may diminish the serum concentration of urinary acidifying agents
chlorpropamide: they may enhance the serum concentration of urinary acidifying agents
mecamylamine: they may diminish the serum concentration of urinary acidifying agents
Actions and Spectrum:
sodium lactate, which is sodium salt of lactic acid, a natural acid produced by the human body during intense exercise or metabolism. sodium lactate has various applications in the food, pharmaceutical, and cosmetic industries and is also used in medical settings as a therapeutic agent.
The action of sodium Lactate:
sodium lactate has several actions, including:
The spectrum of sodium Lactate:
The spectrum of sodium lactate refers to the range of bacteria and fungi it can inhibit. sodium lactate has a broad spectrum of activity against both Gram-positive, Gram-negative bacteria and certain types of fungi. It is generally used as a preservative in meat, poultry products to inhibit the growth of bacteria like as Listeria monocytogenes and Staphylococcus aureus. In addition, sodium lactate has been shown to have antifungal activity against Candida albicans and other types of fungi.
Frequency not defined
Extravasation
Phlebitis
Injection site infections
Thrombosis
Hypervolemia
Febrile response
Black Box Warning:
None
Contraindication/Caution:
Contraindication
Caution
Pregnancy consideration:
US FDA pregnancy category: C
Lactation:
Excreted into human milk is Not known.
Pregnancy category:
Pharmacology:
sodium lactate, which is a salt of lactic acid and sodium hydroxide. Its pharmacology primarily concerns its effects on the body’s acid-base and fluid balance.
When administered intravenously, sodium lactate is rapidly metabolized to bicarbonate, which acts as a buffer in the blood and helps maintain the body’s pH. It is generally used for metabolic acidosis (the body has an excess of acid). By increasing bicarbonate levels, sodium lactate can help to restore the body’s acid-base balance.
sodium lactate also has a mild osmotic effect, meaning it can draw water into the blood vessels and help to increase blood volume. This property makes it helpful in treating hypovolemia (low blood volume) and dehydration.
In cosmetic and personal care products, sodium lactate functions as a humectant, which helps attract and retain moisture in the skin. This property makes it useful in moisturizing products, where it can use to hydrate and soften the skin.
Pharmacodynamics:
Mechanism of action: The action of sodium lactate is primarily related to its effects on the body’s acid-base and fluid balance.
Pharmacokinetics:
Absorption
When administered intravenously, sodium lactate is rapidly absorbed into the bloodstream. When applied topically, sodium lactate can be absorbed through the skin.
Distribution
sodium lactate is distributed throughout the body via the bloodstream. It is primarily distributed in the extracellular fluid compartment.
Metabolism
sodium lactate is metabolized in the liver and muscles to produce energy through anaerobic glycolysis. During this process, lactate is converted back to glucose, which can use as energy.
Elimination and Excretion
The kidneys primarily excrete sodium lactate in the urine. It has a short half-life of 1 hour.
Administration:
sodium lactate is available in different forms and strengths, and the method of administration will depend on the intended use. Here are some common ways in which sodium lactate is administered:
The dosage, method of administration will depend on the individual’s intended use, age, weight, and medical condition. It is essential to follow the instructions a healthcare provider provides or the product label carefully when using sodium lactate.
Patient information leaflet
Generic Name: sodium lactate
Pronounced: [ SOW-dee-um-LAK-tate ]
Why do we use sodium lactate?
sodium lactate has several uses in various industries, including:
sodium lactate is a versatile ingredient with many uses in different industries.
