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Brand Name :
VESIcare
(United States) [Available] ,VESIcare LS
(United States) [Available]Synonyms :
Class :
Anticholinergic Agent and Urinary antispasmodics
Dosage Forms & Strengths
Tablet
5mg
10mg
Dosage Forms & Strengths
Oral suspension
1mg/mL
may enhance the serum concentration of CYP3A4 inhibitors
it may increase the effect of anticholinergic agents
it may increase the effect of anticholinergic agents
it may increase the constipating effect of eluxadoline
CYP3A strong enhancers of the small intestine may reduce the bioavailability of solifenacin
the effect of solifenacin is decreased by lorlatinib, by altering intestinal or hepatic CYP3A4 enzyme metabolism
Adverse drug reactions:
Frequency Defined
>10%
Constipation
Dry mouth
1-10%
Hypertension NOS
Depression NOS
Edema lower limb
Blurred vision
Dizziness
Upper abdominal pain
Dry eyes
Urinary tract infection
Dyspepsia
Nausea
Influenza
Fatigue
Urinary retention
Pregnancy warnings:
Pregnancy Category: N/A
Breastfeeding warnings:
The release of the drug into the human breastmilk is unknown
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits
Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: solifenacin
Pronunciation: SOE-li-FEN-a-sin
Why do we use solifenacin?
solifenacin belongs to the class of Anticholinergics and acts as a Urinary antispasmodic used to treat overactive bladder in adults and Neurogenic Detrusor Overactivity in pediatrics