starch suppository

Action and Spectrum

Actions and Spectrum 

The insertion of starch suppository into the rectum is made easier by their ability to function as lubricants. The starch in the suppository can absorb water when it dissolves or melts in the rectum, softening the stool and increasing the amount of moisture in the rectum. 

Drug Interaction

Adverse Reaction

Frequency not defined  

Pruritus 

Irritation 

Black Box Warning

Black Box Warning 

None

Contraindication / Caution

Contraindication/Caution: 

Contraindication: 

• Known allergy or hypersensitivity to starch or any other ingredients in the suppository. 
• Severe rectal or anal conditions, such as severe inflammation, ulceration, or bleeding. 

Caution: 

• Use of starch suppositories in children and infants should be done under the guidance of a healthcare professional.  
• Caution should be taken in case of rectal bleeding or condition beyond a period of one week. 

Pregnancy / Lactation

Pregnancy consideration:     

Pregnancy category: N/A 

Lactation: Excretion into human milk is unknown  

Pregnancy Categories:         

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology  

Limited information available  

Pharmacodynamics 

The lubricating properties of starch suppositories make it easier to insert the suppository into the rectum. The suppository melts or dissolves at body temperature after being placed, allowing the starch to draw water from the rectal mucosa. 

Pharmacokinetics 

Absorption   

The absorption of water or moisture by the starch, leads in soaking of the rectal area. 

Distribution 

There is no significant distribution of the active ingredient or excipients throughout the body. 

Metabolism 

It is not subject to metabolism in the body.  

Elimination and excretion 

starch suppositories are excreted through the rectum.  

Adminstartion

Administration 

starch suppositories are indicated for rectal administration.

Patient Information Leaflet

Patient information leaflet 

Generic Name: starch suppository 

Why do we use starch suppository? 

starch suppository can be used as a gentle and non-irritating option for relieving occasional constipation. 

starch suppository can be used in the treatment of anal fissures.   

starch suppository may provide relief for individuals with hemorrhoids.