Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Bronco-plus
Synonyms :
Stepronino, Tiofacic, Stepronine, Steproninum
Class :
Expectorant, Mucolytic
Brand Name :
Bronco-plus
Synonyms :
Stepronino, Tiofacic, Stepronine, Steproninum
Class :
Expectorant, Mucolytic
AdultÂ
Dosage Forms & StrengthsÂ
It is used as an investigational and research purposeÂ
Solution (inhalation)Â
810 mgÂ
Respiratory disorders (off-label)Â
In a study with ten healthy volunteers, they took stepronine lysine salt, a drug that helps thin mucus, for ten days at 810 mg per dayÂ
The study found that this treatment did not change the amount or quality of mucous in the stomachÂ
The results suggest that stepronine’s mucus-thinning effect doesn’t impact the stomach’s mucous lining and doesn’t cause harm to the stomachÂ
Dose ModificationsÂ
Limited data is availableÂ
PediatricÂ
Safety and efficacy are not seen in pediatricsÂ
GeriatricÂ
Refer to the adult dosingÂ
the danger or seriousness of adverse effects can be heightened when abatacept is combined with strepronin
the peril or acuteness of adverse effects can be increased when alefacept is combined with stepronin
the peril or acuteness of adverse effects can be increased when adalimumab is combined with stepronin
the jeopardy or severity of infection can be magnified when adenovirus type 7 vaccine live is combined with stepronin
the threat or seriousness of adverse effects can be boosted when aldesleukin is combined with stepronin
the danger or seriousness of adverse effects can be heightened when vinorelbine is combined with stepronin
the peril or acuteness of adverse effects can be elevated when stepronin is combined with voclosporin
the danger or seriousness of adverse effects can be increased when stepronin is combined with vorinostat
the risk or severity of infection can be magnified when yellow fever vaccine is combined with stepronin
the threat or acuteness of adverse effects can be heightened when zidovudine is combined with stepronin
Actions and SpectrumÂ
Thick bronchial secretions can be loosened with the help of mucolytics, where as expectorants tend to increase secretions. Expectorants thin or viscosify bronchial secretions, making it easier for mucus to be expelled by coughing. Mucolytics alter the molecular makeup of mucus molecules. Coughing facilitates the easier removal of mucus because it thins.Â
Limited data is availableÂ
Black Box Warning:Â
Contraindication/Caution:Â
ContraindicationsÂ
CautionsÂ
Pregnancy consideration:Â Â
No data is available regarding the administration of the drug during pregnancy.Â
Breastfeeding warnings:Â Â
No data is available regarding the excretion of drug in breast milk.Â
Pregnancy categories:Â
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.Â
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: No data is available for the drug under this category.Â
PharmacologyÂ
It acts as mucolytic and expectorant.Expectorants are used to drainout the bronchial secretions in the form of mucus while coughing. Whereas mucolytics aids in loosening the thickened secretionsÂ
PharmacodynamicsÂ
The drug decreases the amount of mucus and lubricates the swollen respiratory tract, which helps it to drain from the lungs.Â
PharmacokineticsÂ
Limited information availableÂ
AdministrationÂ
Not availableÂ
Patient information leafletÂ
Generic Name: steproninÂ
Pronounced: steh-proh-ninÂ
Why do we use stepronin?Â
Strepronin acts as a mucolytic and expectorant in treating several respiratory disorders such as bronchitis.Â
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