The Navigation Model of Therapy: Why Awareness Changes Everything
November 16, 2025
Brand Name :
Kimmtrak
Synonyms :
tebentafusp-tebn
Class :
ImmTACs (Immune-mobilising monoclonal TCRs against cancer)
Dosage forms & Strengths:Â
Adult:Â
Injectable solutionÂ
100 mcg/0.5mlÂ
20 mcg intravenously on day 1
30 mcg intravenously on day 8
68 mcg intravenously from the next week until toxicity is reduced
Safety and efficacy are not seen in pediatricsÂ
>10%:Â
Rash Â
Pyrexia Â
Pruritus Â
Glucose increased Â
Fatigue Â
AST increased Â
ALT increased Â
Hemoglobin decreasedÂ
Phosphate decreased Â
Nausea Â
Chills Â
Albumin decreased Â
Abdominal pain Â
Calcium decreased Â
Edema Â
Hypotension Â
Lipase increased Â
Magnesium decreased Â
Alkaline phosphatase increasedÂ
Dry skin Â
Headache Â
Vomiting Â
Sodium decreased Â
Potassium increased Â
Skin hypopigmentation Â
Bilirubin increased Â
DiarrheaÂ
Erythema Â
Amylase increasedÂ
Arthralgia Â
Hair color changes Â
Glucose decreased Â
Potassium decreased Â
Platelet count decreased Â
Neutrophil count decreased Â
Calcium increased Â
1-10%:Â
Pruritus Â
Bilirubin increased Â
Amylase increased Â
Pyrexia Â
Hypotension Â
Glucose increased Â
Abdominal pain Â
Sodium decreasedÂ
Alkaline phosphatase increased Â
Albumin decreased Â
Nausea Â
Neutrophil count decreased Â
Potassium increased Â
Calcium decreased Â
Diarrhea Â
VomitingÂ
<1%:Â
CRSÂ Â
Arthralgia Â
Potassium decreased Â
Hemoglobin decreased Â
Chills Â
HeadacheÂ
Tebentafusp is contraindicated in patients hypersensitive to the active ingredient.Â
Pregnancy consideration:Â Â
No data is available regarding the use of the drug in pregnant females.Â
Breastfeeding warnings:Â Â
No data is available regarding the excretion of the drug in breast milk.Â
Pregnancy category:Â
Patient information leafletÂ
Generic Name: tebentafuspÂ
Pronounced: teb-en-tah-fuspÂ
Why do we use tebentafusp?Â
Tebentafusp belongs to ImmTACs. It is used to treat uveal melanoma.  Â