- March 15, 2022
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Brand Name :
Vemlidy
Synonyms :
Tenofovir alafenamide
Class :
Antiviral agents and Anti-HBV (Reverse Transcriptase Inhibitors
Dosage Forms & Strengths
Tablet, Oral:
25 mg
Note: Discontinuation of tenofovir alafenamide for hepatitis B therapy, can result in severe acute exacerbations of hepatitis B.
No safe and efficacious dose described
Refer to adult dosing
may have an increased nephrotoxic effect when combined with tenofovir products
may have an increased nephrotoxic effect when combined with tenofovir products
may have an increased nephrotoxic effect when combined with tenofovir products
may have an increased nephrotoxic effect when combined with tenofovir products
may have an increased nephrotoxic effect when combined with tenofovir products
Ritonavir may reduce the therapeutic effects of Tenofovir alafenamide, avoid a combination
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
tenofovir alafenamide: they may diminish the serum concentration of rifabutin
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
may increase the risk of adverse effect of other reverse transcriptase inhibitors
reverse transcriptase inhibitors increase the concentration of ergonovine in the serum
May increase plasma concentration and therapeutic effects of other antiretroviral drugs
May increase plasma concentration and therapeutic effects of other antiretroviral drugs
Tenofovir alafenamide increases the serum concentrations of pantoprazole, dose adjustments may be suggested to avoid toxicity
May enhance the therapeutic concentration of Tenofovir alafenamide
Coadministration of Tenofovir alafenamide with warfarin can increase the risk of bleeding or unusual bleeding
may enhance the serum concentration when combined with ganciclovir-valganciclovir
It may enhance the effect when combined with tafamidis meglumine
Frequency defined:
>10%:
Headache
Decreased bone mineral density
1% to 10%:
Skin rash
Increased serum creatine kinase
Abdominal pain
Diarrhea
Dyspepsia
Flatulence
Nausea
Vomiting
Fatigue
Arthralgia
Back pain
Cough
Frequency not defined:
Exacerbation of hepatitis B
Pregnancy consideration: Tenofovir alafenamide can transfer in minor amounts across the human placenta.
Lactation: Tenofovir alafenamide excretion in breast milk is not known.
Pregnancy category:
Patient information leaflet
Generic Name: Tenofovir alafenamide
Pronunciation: Tenofovir alafenamide
Why do we use Tenofovir alafenamide?
It is used to treat viral infections such as Hepatitis B infection.
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