New Pathway Identified: Splenic Tr1 Cells Drive Transplant Tolerance via Areg–EGFR Signaling
January 8, 2026
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It may enhance the effect when combined with grapefruit by CYP3A4 metabolism
When tezacaftor is used together with ouabain, this leads to reduction in tezacaftor excretion
the effect of tezacaftor is decreased by lorlatinib, by altering intestinal or hepatic CYP3A4 enzyme metabolism
tezacaftor increases the effect of mestranol by altering the intestinal/ hepatic CYP3A4 enzyme metabolism
metronidazole enhances the effect of tezacaftor by altering the intestinal or hepatic CYP3A4 enzyme metabolism