tick-borne encephalitis vaccine

Action and Spectrum

Actions and Spectrum 

Inactivated vaccines contain killed virus particles and viral proteins. When the vaccine is administered, it stimulates the immune system to recognize these viral components as foreign and mount an immune response.

Drug Interaction

Adverse Reaction

Frequency defined  

>10% 

Injection site tenderness  

Local pain 

Headache  

Local pain  

Injection site tenderness  

1-10% 

Muscle pain 

Fatigue  

Headache  

Fever  

Restlessness  

Post marketing Reports 

Hypersensitivity 

Visual impairment 

Herpes zoster  

Anaphylactic reaction 

Photophobia 

Tachycardia 

Eye pain 

Tinnitus 

Black Box Warning

Black Box Warning 

None 

Contraindication / Caution

Contraindication/Caution: 

Contraindication: 

• If an individual is known to be allergic to any of the components of the TBE vaccine, vaccination may be contraindicated. 
• Individuals who have had a severe allergic reaction to a previous dose of the TBE vaccine or any of its components should not continue with further doses. 

Caution: 

• Vaccination may be delayed in individuals with moderate or severe acute illnesses.  
• Caution may take in individuals with bleeding disorders or thrombocytopenia.

Pregnancy / Lactation

Pregnancy consideration: 

Pregnancy category: N/A 

Lactation: Excretion into human milk is unknown  

Pregnancy Categories:         

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester. 

Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women. 

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits. 

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women. 

Category N: There is no data available for the drug under this category. 

Pharmacology

Pharmacology  

When the inactivated vaccine is administered, it triggers the immune system to recognize the viral components as foreign. This recognition leads to the production of antibodies specific to the tick-borne encephalitis virus. 

Pharmacodynamics 

Tick-borne encephalitis vaccination is the production of antibodies, which are proteins that can specifically recognize and neutralize the tick-borne encephalitis virus. 

Pharmacokinetics 

Limited information available on ADME. 

Adminstartion

Administration 

Tick-borne encephalitis vaccine is administered via intramuscularly in suspension form.

Patient Information Leaflet

Patient information leaflet 

Generic Name: tick-borne encephalitis vaccine 

Why do we use tick-borne encephalitis vaccine? 

The tick-borne encephalitis vaccine indicated in the prevention of tick-borne encephalitis.  

The vaccine helps reduce the risk of contracting the virus and developing the associated neurological complications.