- March 15, 2022
- Newsletter
- 617-430-5616
Menu
Menu
Menu
Menu
Menu
Menu
Brand Name :
Ultram, conzip, qdolo
Synonyms :
Tramadol, tramadolum
Class :
Opiod analgesics
Dosage Forms & Strengths
Tablet
Immediate release:
50mg
100mg
Extended release:
100mg
150mg
200mg
300mg
Oral solution
5mg/ml
Immediate release Acute:
50 - 100
mg
Orally
every 6 hrs
Tablets
Do not exceed 400mg/day
Chronic:
Initial dose-25mg orally everyday morning
Maintenance dose-25-50mg/day for every three days
Final dose-50-100mg orally every 4-6 hours.Do not exceed 400mg/day
Extended-release
100mg orally daily once, up to 100mg/day for every five days.Do not exceed 300mg/day
Oral Solution
Initial dose-25mg/day orally ,increase the dosage by 25 mg every three days
Do not exceed 400mg/day
Dose Adjustments
Renal impairment
CrCl<30ml/min: No dosage adjustment is needed
CrCl>30ml/min: 50-100mg orally every 12 hour
Hepatic impairment
No dosage adjustment is necessary
Refer adult dosing
may increase the central nervous system depressant effect
may increase the central nervous system depressant effect
may increase the central nervous system depressant effect
may enhance the CYP3A4 substrate serum concentration
may increase the central nervous system depressant effect
may increase the central nervous system depressant effect
may decrease the opiod agonists therapeutic effect
may increase the central nervous system depressant effect
may decrease the opiod agonists therapeutic effect
It may enhance serotonin levels when combined with tramadol
It may enhance serotonin levels when combined with tramadol
It may enhance toxicity when combined with tramadol by serotonin levels
It may enhance serotonin levels when combined with tramadol
phenobarbital: they may increase the CNS depressant effect of tramadol
CYP3A strong enhancers of the small intestine may reduce the bioavailability of tramadol
it increases the effect of CNS depressants
it increases the effect of CNS depressants
CNS depressants increase the CNS depressing effect of paraldehyde
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance serotonin levels when combined with tramadol
It may enhance serotonin levels when combined with tramadol
It may enhance effects when combined with tramadol by pharmacodynamic synergism
It may enhance serotonin levels when combined with tramadol
It may enhance serotonin levels when combined with tramadol
may increase the toxic effect of Monoamine Oxidase Inhibitors
antiemetics increase the serotonergic effect of tramadol
antiemetics increase the serotonergic effect of tramadol
antiemetics increase the serotonergic effect of tramadol
antiemetics increase the serotonergic effect of tramadol
tramadol: they may enhance the serum concentration of digoxin
tramadol: they may diminish the serum concentration of CYP3A4 Inducers
tramadol: they may diminish the serum concentration of CYP3A4 Inducers
tramadol: they may diminish the serum concentration of CYP3A4 Inducers
tramadol: they may diminish the serum concentration of CYP3A4 Inducers
tramadol: they may diminish the serum concentration of CYP3A4 Inducers
tramadol and mephenesin, when used together, the risk or seriousness of CNS depression may rise
the effect of tramadol is decreased by lorlatinib, by altering intestinal or hepatic CYP3A4 enzyme metabolism
ondansetron increases the serotonergic effect of tramadol
antiemetics increases the serotonergic effect of tramadol
antiemetics increases the serotonergic effect of tramadol
perampanel may enhance the CNS depressant effect of CNS Depressants
it increases the effect of CNS depressants
it increases the effect of CNS depressants
when combined, it may increase sedation
may increase the level of effectiveness through P-glycoprotein MDR1 efflux transporter
when combined, it may increase sedation
may increase the toxic effects
may increase the serum concentrations of CYP2D6 inhibitors
It may enhance serotonin levels when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
It may enhance sedation when combined with tramadol
Frequency defined:
>10%
Immediate release
Asthenia
Headache
Vomiting
CNS stimulation
Dizziness
Dyspepsia
Extended-release
Dry mouth
Headache
Vomiting
Nausea
Constipation
1-10%
Immediate release
Anorexia
Confusion
Hypertonia
Dry mouth
Abdominal pain
Rash
Sweating
Urinary frequency
Flatulence
Extended-release
Anorexia
Sweating
Asthenia
Insomnia
Fever
Prostatic disorder
Depression
Myalgia
Peripheral edema
Vasodilation
<1%
Immediate release
Dyspnea
Syncope
Weight loss
Menstrual disorder
Urticaria
Tachycardia
Amnesia
Seizure
Extended-release
Anemia
Arthritis
Pneumonia
Eye disorder
Dysuria
Leg cramps
Post-marketing reports
Delirium
Mydriasis
Hypoglycemia
Androgen deficiency
Hyponatremia
Pregnancy consideration: Insufficient data available
Lactation: The drug is excreted in the human breast milk
Pregnancy category:
Patient information leaflet
Generic Name: tramadol
Pronounced: [ tra’ ma doll]
Why do we use tramadol?
It is used to treat mild to moderate pain in adults
ADVERTISEMENT
Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
USA – BOSTON
60 Roberts Drive, Suite 313
North Adams, MA 01247
INDIA – PUNE
7, Shree Krishna, 2nd Floor, Opp Kiosk Koffee, Shirole Lane, Off FC Road, Pune 411004, Maharashtra
