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Brand Name :
Trazodone D, Oleptro, Desyrel Dividose, Desyrel
Synonyms :
Class :
Antidepressants and antianxiety drugs; Atypical antidepressants
Brand Name :
Trazodone D, Oleptro, Desyrel Dividose, Desyrel
Synonyms :
Class :
Antidepressants and antianxiety drugs; Atypical antidepressants
Dosage forms & Strengths:
Adult:
Tablet:
50 mg
100 mg
150 mg
300 mg
Extended-release tablet:
150 mg
300 mg
For more than 12 years, 25-50 mg orally per day
Increase the dose by 100-150 mg
gilteritinib may enhance the QTc-prolonging effect of QT-prolonging Agents
may enhance the serum concentration of CYP3A4 inhibitors
may enhance the QTc-prolonging effect of QT-prolonging agents
may enhance the QTc-prolonging effect of QT-prolonging agents
may enhance the QTc-prolonging effect of QT-prolonging agents
may enhance the QTc-prolonging effect of QT-prolonging agents
may enhance the QTc-prolonging effect of QT-prolonging agents
may increase the QTc prolonging effect
CYP3A strong enhancers of the small intestine may reduce the bioavailability of trazodone
when used together, entrectinib and trazodone both increase the QTc interval
when used together, encorafenib and trazodone both increase the QTc interval
it may enhance the QTc-prolonging effect of terfenadine
may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents
may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents
may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents
may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents
may enhance the QTc-prolonging effect of QT-prolonging Miscellaneous Agents
Selective Serotonin Reuptake Inhibitors may enhance the hypoglycemic effect of Agents with Blood Glucose Lowering Effects
Selective Serotonin Reuptake Inhibitors may enhance the hypoglycemic effect of Agents with Blood Glucose Lowering Effects
Selective Serotonin Reuptake Inhibitors may enhance the hypoglycemic effect of Agents with Blood Glucose Lowering Effects
Selective Serotonin Reuptake Inhibitors may enhance the hypoglycemic effect of Agents with Blood Glucose Lowering Effects
Selective Serotonin Reuptake Inhibitors may enhance the hypoglycemic effect of Agents with Blood Glucose Lowering Effects
may enhance the anticoagulant effect of Vitamin K antagonists
may enhance the anticoagulant effect of Vitamin K antagonists
may enhance the anticoagulant effect of Vitamin K antagonists
may enhance the anticoagulant effect of Vitamin K antagonists
may enhance the anticoagulant effect of Vitamin K antagonists
may enhance the antiplatelet effect of NSAIDs
may enhance the antiplatelet effect of NSAIDs
may enhance the antiplatelet effect of NSAIDs
may enhance the antiplatelet effect of NSAIDs
may enhance the antiplatelet effect of NSAIDs
may increase the hypoglycemic effect
may increase the hypoglycemic effect
may increase the hypoglycemic effect
may increase the hypoglycemic effect
may increase the hypoglycemic effect
they increase the QTc prolongation effect of other QT-prolonging agents
they increase the QTc prolongation effect of other QT-prolonging agents
they increase the QTc prolongation effect of other QT-prolonging agents
they increase the QTc prolongation effect of other QT-prolonging agents
they increase the QTc prolongation effect of other QT-prolonging agents
increase the therapeutic effect of daunorubicin by P-glycoprotein efflux transporter
the effect of trazodone is decreased by lorlatinib, by altering intestinal or hepatic CYP3A4 enzyme metabolism
decrease level of docetaxel
it increases the effect or level of ruxolitinib by altering the intestinal or hepatic CYP3A4 enzyme metabolism
increase the therapeutic effect of idarubicin by P-glycoprotein efflux transporter
may enhance the Qtc prolonging effect
they increase the QTc prolongation effect of other QT-prolonging agents
they increase the QTc prolongation effect of other QT-prolonging agents
they increase the QTc prolongation effect of other QT-prolonging agents
they increase the QTc prolongation effect of other QT-prolonging agents
they increase the QTc prolongation effect of other QT-prolonging agents
trazodone and dicyclomine decrease the cholinergic transmission
may increase the level of each other by unknown mechanism
>10%:
Blurred vision
Dizziness
Drowsiness
Dry mouth
Fatigue
Headache
Nausea/vomiting
1-10%:
Constipation
Edema
Confusion
Disorientation
Incoordination
Nasal congestion
Orthostatic hypotension
Syncope
Tremor
Weight change
Ejaculation disorder
Decreased libido
<1%:
Priapism
Sedation
Alopecia
Anxiety
Acne
Anemia
Increased apetite
Diplopia
Insomnia
Urinary retention
Vertigo
Trazodone is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients.
Pregnancy consideration:
Trazodone should be used during pregnancy only when very much required
Breastfeeding warnings:
Use the drug cautiously during lactation.
Pregnancy category:
Patient information leaflet
Generic Name: trazodone
Pronounced: tra-zo-done
Why do we use trazodone?
Trazodone treats depression and insomnia and helps in alcohol/smoking cessation.