A Milestone Moment: FDA Approves Addyi® for Hypoactive Sexual Desire Disorder in Postmenopausal Women
December 17, 2025
Brand Name :
Dyazide, Maxzide
Synonyms :
Class :
Potassium sparing diuretics and thiazide Combos
Dosage Forms & Strengths
Capsule
37.5mg/25mg- triamterene/hydrochlorothiazide
50mg/25mg – triamterene/hydrochlorothiazide
Tablet
37.5mg/25mg – triamterene/hydrochlorothiazide
75mg/50mg – triamterene/hydrochlorothiazide
1-2 tablets/capsules 37.5mg/25mg (triamterene/hydrochlorothiazide) or
50mg/25mg (triamterene/hydrochlorothiazide) orally every Day
1 tablet 75mg/50mg (triamterene/hydrochlorothiazide) orally every Day
1-2 tablets/capsules 37.5mg/25mg (triamterene/hydrochlorothiazide) or
50mg/25mg (triamterene/hydrochlorothiazide) orally every Day
1 tablet 75mg/50mg (triamterene/hydrochlorothiazide) orally every Day
1 tablet of 75 mg triamterene and 50 mg HCTZ orally every day
1-2 tablets/capsules of 37.5-50 mg triamterene and 25 mg HCTZ orally every day
Adverse drug reactions:
Frequency Not Defined
Triamterene
Xerostomia
Photosensitivity
Weaknes
Headache
Jaundice
Diarrhea
Nausea
Azotemia
Dizziness
Fatigue
Rash
Vomiting
Hydrochlorothiazide
Hyperglycemia
Anorexia
Stevens-Johnson syndrome
Hypotension
Dizziness
Phototoxicity
Toxic epidermal necrolysis
Fever
Epigastric distress
Alopecia
Erythema multiforme
Glycosuria
Hypokalemia
Pregnancy warnings:
AU TGA pregnancy category: C
US FDA pregnancy category: C
Lactation:
Excreted into human milk is known (hydrochlorothiazide); Unknown (triamterene)
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: triamterene/hydrochlorothiazide
Why do we use triamterene/hydrochlorothiazide?
triamterene/hydrochlorothiazide is a Potassium sparing diuretics and thiazide Combos which is used to treat hypertension and edema.