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Brand Name :
Neko (Daily Hygiene Soap)
Synonyms :
triclocarban
Class :
Skin Antiseptics & Disinfectants
Brand Name :
Neko (Daily Hygiene Soap)
Synonyms :
triclocarban
Class :
Skin Antiseptics & Disinfectants
Dosage Forms & Strengths
Soap
30 gm
75 gm
100 gm
At the time of bath, gently massage on body surface topically and rinse with warm water
Dosage Forms & Strengths
Soap
30 gm
75 gm
100 gm
For 13 to 18 years old:
At the time of bath, gently massage on body surface and rinse with warm water
Refer to adult dosing
Actions and Spectrum
triclocarban is effective against a wide range of bacteria. It works by disrupting the cell membranes of bacteria, which leads to their death. It primarily targets Gram-positive bacteria but can also have some activity against Gram-negative bacteria.
Frequency not defined
None
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
triclocarban works by disrupting the cell membranes of bacteria and fungi, leading to their death.
It interferes with the microbial fatty acid synthesis pathway, which is essential for the formation and maintenance of cell membranes in these microorganisms.
Pharmacodynamics
triclocarban has antimicrobial effects that are active while it is in contact with the skin and the target microorganisms.
This disruption of cell membranes leads to cell death in bacteria and fungi and makes triclocarban effective at reducing the growth and presence of these microorganisms on the skin.
Pharmacokinetics
Limited information available on ADME.
Administration
triclocarban is available in form of soap for topical use.
Patient information leaflet
Generic Name: triclocarban
Why do we use triclocarban?
Neko (triclocarban) is used in soaps and body washes as an antimicrobial ingredient.
triclocarban is intended to reduce the growth of bacteria and fungi on the skin, providing a sense of cleanliness.
It also helps in keeping the skin odour and germ free, supple, and soft.
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