DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Frequency undefined: 

Sedation 

Fatigue 

Dry mouth 

Constipation 

Blurred vision 

Weakness 

Lethargy 

Headache 

Agitation 

Insomnia 

Nausea 

Vomiting 

Anxiety 

Sweating 

Confusion 

EPS 

Dizziness 

Tinnitus 

Paresthesia 

Orthostatic hypotension 

ECG changes 

Tachycardia 

Incr LFTs 

Sexual dysfunction 

Rash 

Seizure 

Trimipramine is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients. 

Pregnancy consideration:  

Category C. 

Breastfeeding warnings:  

Avoid lactation during the treatment of trimipramine. 

Pregnancy category: 

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester. 
• Category B: No evidence shows the risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women.    
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a product in humans; Pregnant women must take care of the potential risks. 
• Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms. However, despite potential dangers may be used only in emergency cases for potential benefits. 
• Category X: Drugs listed in this category outweigh the risks over the benefits. The drug is not for pregnant women. 
• Category N: No data is available for the drug under this category. 

 

Patient information leaflet 

Generic Name:  trimipramine 

Pronounced: tri-mi-prah-mine 

Why do we use trimipramine? 

Trimipramine treats depression.