Microbiome–Nutrition Interactions in Early Life and Their Association With Childhood Systolic Blood Pressure
February 17, 2026
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Brand Name :
Viru-Merz
Synonyms :
tromantadine
Class :
Topical Antivirals
Dosage Forms & Strengths
Gel
1%
Apply 1% gel topically on the affected area of skin for 3 to 5 times daily
Not determined
Refer to adult dosing
Actions and Spectrum
tromantadine primarily works by preventing the virus from entering host cells. It does this by interfering with the fusion of the virus envelope with the host cell membrane. This inhibition of virus entry prevents the virus from infecting new cells.
Frequency not defined
Increased itching
Pain
Redness
Nodule formation
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
tromantadine prevents the viruses from entering host cells. It does this by interfering with the fusion of the viral envelope with the host cell membrane.
This inhibition prevents the virus from gaining access to the cellular machinery it needs for replication.
Pharmacodynamics
tromantadine’s effect is its potent antiviral activity against herpes simplex viruses.
By inhibiting viral entry, it reduces the severity and duration of symptoms associated with HSV infections.
Pharmacokinetics
Absorption
tromantadine is absorbed through the skin or mucous membranes at the site of application.
Distribution
tromantadine distributes to the local tissues.
Metabolism
tromantadine undergoes minimal metabolism in the body.
Elimination and excretion
tromantadine is eliminated through the kidneys.
Administration
tromantadine is applied topically and it is available in the form of gel.
Patient information leaflet
Generic Name: tromantadine
Why do we use tromantadine?
tromantadine is indicated for the treatment of certain viral infections, caused by herpes simplex viruses (HSV).
tromantadine is used topically to treat oral and genital herpes.
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