From Data to Decisions: Tailoring Treatment for Pituitary Tumors
February 3, 2026
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Brand Name :
Sanvar
Synonyms :
vapreotide
Class :
Anti-neoplastic agents, Somatostatin agent
Brand Name :
Sanvar
Synonyms :
vapreotide
Class :
Anti-neoplastic agents, Somatostatin agent
Dosage Forms & Strengths
Intravenous solution
50 mcg
Indicated for Bleeding esophageal varices
:
Administer 50 microgram (mcg) intravenous bolus, then continue the infusion for five days at a rate of 50 mcg per hour. After starting the continuous infusion, endoscopic therapy was supposed to start within 12 hours.
Not determined
Actions and Spectrum:
Vapreotide is a naturally occurring hormone. It inhibits the release of various hormones in the body.
Frequency not defined
mild abdominal cramps
Hyperglycemia
Black box warning:
None
Contraindications/caution:
The drug is contraindicated in following situations:
Hypersensitivity
Gallstones
Severe Bradycardia
Endocrine Disorders
Pregnancy Warnings:
Pregnancy category: N/A
Lactation:
Excretion of the drug in human breast milk is unknown
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.
Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology:
It will decrease the release of growth hormones from the pituitary gland.
Pharmacodynamics:
Vapreotide has vasoconstrictive effects, which can reduce splanchnic blood flow in the body.
Pharmacokinetics:
Limited information is available on ADME.
Administration:
It is administered subcutaneously and intravenously as an injection.
Patient information leaflet
Generic Name: vapreotide
Why do we use vapreotide?
Vapreotide is indicated in the treatment of acromegaly.
It is effective in the treatment of AIDS, which is related to diarrhea.
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