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Brand Name :
xenoview
Synonyms :
xenon Xe 129 hyperpolarized
Class :
Diagnostic imaging agent
Dosage Forms & StrengthsÂ
Oral inhalation, gasÂ
In a volume of 250-750 mL total xenon, each 1,000-mL dose delivery bag contains at least 75mL dose equivalent (DE) of hyperpolarized xenon Xe 129Â
Oral inhalation of 75–100 mL dose equivalent (DE) of hyperpolarized xenon Xe 129
Lung ventilation evaluation
<12 years: Safety and efficacy not established
>12 years: Oral inhalation of 75–100 mL dose equivalent (DE) of hyperpolarized xenon Xe 129
Refer adult dosingÂ
Frequency not defined:Â Â
HeadacheÂ
HypersensitivityÂ
Increased heart rateÂ
TinglingÂ
EuphoriaÂ
Oropharyngeal painÂ
DizzinessÂ
Blood oxygen desaturationÂ
NumbnessÂ
DizzinessÂ
Pregnancy consideration: Not recommended to useÂ
Lactation: Breastfeeding is not suggestedÂ
Pregnancy category:Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.  Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: There is no data available for the drug under this categoryÂ
Patient information leafletÂ
Generic Name: xenon Xe 129 hyperpolarizedÂ
Pronounced: (Zee-non Xe 129 hy-per-po-lar-ized)Â
Why do we use xenon Xe 129 hyperpolarized?Â
Hyperpolarized xenon-129 (129Xe) is a radioactive isotope of xenon that has been used in some medical research studies. Xenon is a noble gas that is naturally present in the atmosphere and is chemically unreactive, which makes it safe to use in medical imaging. When hyperpolarized, the xenon atoms are aligned in a specific way, making them more sensitive to magnetic fields. This property can be used to study the function of the lungs and other organs in the body.Â
One of the primary uses of hyperpolarized xenon-129 is in magnetic resonance imaging (MRI), where it can be used to measure the diffusive properties of gases in the body, such as oxygen and carbon dioxide. This information can help researchers and doctors better understand how the body’s tissues function and identify any abnormalities. Hyperpolarized xenon-129 has also been used in other medical research studies to investigate the role of oxygen in cancer, heart disease, and other conditions. However, further research is needed to determine the full range of potential uses for this technology.Â