How does childhood trauma impair muscle function in adulthood?

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  • Chronic stress
  • Alterations in hormonal balance
  • Prolonged exposure to higher cortisol levels
  • Development of mental health conditions
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      A recent study examined the function of skeletal muscle of older adults paired with surveys of adverse events they had experienced in childhood. It revealed that people who experienced greater childhood adversity, reporting one or more adverse events, had poorer muscle metabolism later in life. What these results suggest is that these early formative childhood experiences have the ability to get under the skin and influence skeletal muscle mitochondria, which is important because mitochondrial function is related to a host of aging-related outcomes. The researchers say the effects of childhood adverse events remained significant even after they controlled for other factors that could potentially impact muscle function such as age, gender, educational attainment, parental education, body mass index, number of depressive symptoms, smoking status, and physical activity.

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